This list contains only the countries for which job offers have been published in the selected language (e.g., in the French version, only job offers written in French are displayed, and in the English version, only those in English).
NewLimit is recruiting a Head of Translation to lead our therapeutic programs from discovery to the clinic. Our active programs are focused on restoring youthful hepatic metabolism, vascular endothelial integrity, and T cell immunity in aged and diseased patients. In this role, you will lead the validation and preclinical development of reprogramming medicines through regulatory filing to early clinical development. You will serve as the company’s senior preclinical development scientist and as a member of our executive team.
Job Responsibility:
Lead preclinical development and preparing regulatory filings (IND, CTNs, and others) for reprogramming medicines. You will be the primary owner of progress for our therapeutic assets
Manage all Therapeutic Area teams and coordinate with others to establish preclinical models, validate payloads, and complete development candidate selections
Solve the logistical bottlenecks that block progress of our therapies. This may involve coordinating CMC timelines, planning study schedules, or sourcing precious preclinical samples. You will get your hands dirty
Serve as a member of NewLimit’s Executive Team and contribute to budgeting, goal setting, and technical review decisions
Recruit, manage, and mentor scientists and therapeutic developers throughout the company
Requirements:
Ph.D. in molecular biology, developmental biology, chemistry or a related discipline or M.D./Pharm.D. and relevant clinical training or ≥5 years of equivalent industry experience
Experience leading therapeutic programs through the investigational new drug application process
History of technical contributions to therapeutic programs as a biologist, chemist, or computational scientist
Experience managing substantial budgets and making go/no-go decisions
Nice to have:
Experience contributing to a 0 → 1 medicine that was first-in-class for a new target category or modality
Experience contributing to nucleic acid medicines (mRNA, RNAi, ASO)
History of contributions in one of our current therapeutic areas (hepatic metabolism, vascular biology, immunology)
Experience leading program teams across multiple therapeutic areas
Experience with regulatory filings across multiple geographies (US, AUS/NZ, EU, MENA)
What we offer:
Health, dental, and vision insurance
401(k) with company match
Industry-leading paid time off (PTO) -- 20 days/year for all employees + holidays