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The Head of Operations is responsible for leading all Production and Warehouse activities within Quantum Aseptic Services. The role acts as the Head of Production as defined under EudraLex Volume 4, Chapter 2, and is accountable for ensuring that products are manufactured and stored in accordance with GMP, approved documentation and regulatory requirements to achieve the required quality standards.
Job Responsibility:
Lead day-to-day aseptic manufacturing and warehouse operations
Ensure safe, efficient and compliant production of aseptically prepared parenteral products
Develop and implement operational strategy aligned with corporate goals
Monitor and report KPIs relating to safety, quality, delivery and cost
Ensure products are produced and stored according to approved documentation and GMP requirements
Approve production instructions and ensure strict implementation
Ensure production records are reviewed, evaluated and signed by authorised personnel
Ensure departmental premises, utilities and equipment are qualified, maintained and fit for purpose
Ensure appropriate process validation, revalidation and qualification activities are completed and maintained
Ensure contamination control strategies are implemented, particularly for aseptic and cytotoxic operations
Joint ownership of the Pharmaceutical Quality System (PQS)
Approval of controlled documents and amendments relating to operations
Monitoring of environmental controls and cleanroom performance
Ensuring plant hygiene standards are maintained
Participation in validation strategy and oversight of validation activities, including as part of service and strategy improvements
Approval and monitoring of suppliers and outsourced GMP-related service providers
Designation and monitoring of storage conditions for materials and finished products
Monitoring compliance with GMP and GDP requirements
Participation in deviation investigations and quality issue escalation
Participation in management review and advocacy for continual improvement
Ensure structured GMP training programmes are established and maintained
Approve departmental training programmes and ensure effectiveness is assessed
Ensure specific contamination control training for aseptic and cytotoxic environments
Ensure compliant storage and distribution of materials and finished products
Maintain GDP compliance for finished product logistics
Monitor stock control, inventory accuracy and environmental conditions
Ensure supplier qualification and performance monitoring
Requirements:
Degree in Pharmaceutical Sciences, Engineering or related discipline is desirable