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Head of Medicinal Chemistry

China, Shanghai 1000000.00 - 1200000.00 CNY / Year · Job Posted May 12, 2026
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Job Description

The Director of Medicinal Chemistry will spearhead the small-molecule R&D strategy in Shanghai, leading a high-performing team to advance projects from hit identification through PCC selection to IND submission. This role requires a blend of deep scientific expertise and strategic leadership within a fast-paced, innovation-driven environment.

Job Responsibility

  • Formulate and execute R&D strategies
  • Make critical decisions on project direction, resource allocation, and risk management
  • Lead SAR optimization and molecular design based on structural biology and computational chemistry
  • Apply cutting-edge modalities such as PROTACs, covalent inhibitors, and AI-assisted drug design
  • Partner with Biology, DMPK, and Toxicology teams to balance physico-chemical properties and ADMET profiles
  • Recruit, mentor, and motivate a team of chemists, ensuring the highest standards of scientific rigor and data quality

Requirements

  • Ph.D. in Organic or Medicinal Chemistry
  • Minimum 8 years of experience in small-molecule drug discovery within Multinational Corporations (MNCs) or top-tier industry leaders
  • Direct experience advancing at least one project to PCC
  • Proven track record of successful IND submissions
  • Prior experience managing a medicinal chemistry team of at least 5+ members

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