CrawlJobs Logo

Global Therapeutic Research Lead (Oligo)

Japan, Kanagawa Employment contract · Job Posted June 26, 2026
Apply Position
Job Link Share

Job Description

Leveraging a proven track record of leading at least 3 discovery programs to clinic, The Global Therapeutic Research Lead (G-TRL) is a pipeline critical strategic leader responsible for driving Research projects to the clinic. The individual will sit on the Neuroscience Drug Discovery Unit (NS DDU) Leadership Team. Leader for at least one or more of Takeda's top priority oligonucleotide projects with substantial clinical and commercial potential with a clear accelerated path to the clinic. You will provide mentorship to team members to elevate enterprise thinking and capabilities of our drug discovery talent across the global Research function. As project lead, the G-TRL builds a connected view of the project within the Neuroscience TA strategy and treatment paradigm and can represent all core expertise at depth and align with stakeholders and sponsors across the organization including Research, Clinical Development and Commercial stakeholders and executive level governance committees. G-TRLs are responsible for creating the medicine vision, early asset strategy and managing multiple external partnerships that accelerate delivery of the project. G-TRLs will establish smart, fast, and critical path minded practices for groups, including integrating new strategies and competitive industry ways of working. G-TRL will advise on the continuous infusion of new Research projects aligned to strategy to generate a sustainable Research Engine generating a steady flow of high-quality INDs every year.

Job Responsibility

  • Lead and manage one or more 'Top 10' drug discovery oligonucleotide projects, overseeing the entire drug discovery process from target identification to preclinical development
  • Responsible for the articulation and ownership of the project strategy, developed in partnership with internal stakeholders
  • Contribute to strategy for future portfolio investment, particularly within the Inflammation and Immunology area including advising on which projects should be Top 10 projects
  • Evaluate and prioritize potential drug candidates based on scientific, medical, and commercial considerations
  • Represent all core expertise for project
  • Partner with Clinical and Translational teams to refine asset strategy
  • Ensure alignment to the therapeutic area strategy (i.e., Clinical Development)
  • Understand and align with commercial team for asset commercial value within the Neuroscience Therapeutic Area (NS TA)
  • Provide guidance and mentorship to global project team members, stimulating enterprise thinking and fostering their professional growth and development
  • Mentor future and more junior project leads and elevate drug discovery capability across Research
  • Collaborate with cross-functional teams and partners (e.g., DMPK, Pharmaceutical Sciences) within and outside Takeda to drive project delivery
  • Pipeline and enterprise impact through effective partnering with multiple internal and external collaborators
  • Provide strategic, process, and operational leadership for successful Top 10 Project delivery
  • Foster a culture of innovation and scientific excellence within the matrixed drug discovery team, promoting collaboration, knowledge sharing, and continuous learning
  • Become a world leading scientific expert in the projects you lead
  • Oversee the design and execution of experiments, data analysis, and interpretation to enable decision-making and optimize drug discovery efforts
  • Stay abreast of the latest advancements in drug discovery, emerging technologies, and industry trends, applying this knowledge to enhance drug discovery strategies
  • Build and maintain relationships with key stakeholders, including academic institutions, research organizations, and industry partners inclusive of serving on joint external governance committees across the globe
  • Represent Takeda externally for the Neuroscience Drug Discovery Unit and play a key role in evaluating external opportunities, serving as an effective ambassador for Takeda's global business development brand

Requirements

  • Advanced degree in health or life sciences (e.g., Ph.D., M.D., D.V.M.)
  • Expected to have at least 10-12 years industry and relevant subject matter expertise within Immunology and Inflammation and at least 10-12 years global management experience, including working effectively with matrix teams
  • Extensive experience in leading drug discovery teams and managing drug discovery/development projects, preferably in a pharmaceutical or biotechnology setting covering gastroenterology and inflammation
  • Deep understanding of the drug discovery process, including target identification, hit-to-lead optimization, and preclinical development, anticipating, and removing roadblocks
  • Proven track record of leading numerous projects, ideally 5+ projects, across discovery from target inception to Candidate Nomination or beyond
  • Played a major role in 3+ INDs
  • Has delivered clinical development assets preferably across multiple modalities (e.g. small molecule, biologics, cell therapies, ADC etc.)
  • Excellent and inclusive leadership with the ability to inspire and motivate diverse teams towards achieving ambitious goals
  • Reputation as a proactive, solutions-oriented leader who engages relevant expertise no matter where it resides
  • Strong business acumen and understanding of the pharmaceutical industry, including regulatory requirements and commercial considerations with relevant knowledge and expertise for specific modalities
  • Exceptional communication and presentation skills, with the ability to effectively communicate complex scientific concepts to diverse audiences
  • Proven ability to build and maintain collaborative relationships with internal and external stakeholders across a matrixed organization
  • Strong problem-solving and decision-making abilities, with a focus on data-driven decision making
  • Demonstrated success in building and managing strategic partnerships with academic institutions, research organizations, and industry collaborators

What we offer

  • Allowances: Commutation, Housing, Overtime Work etc.
  • Salary Increase: Annually, Bonus Payment: Twice a year
  • Holidays: Saturdays, Sundays, National Holidays, May Day, Year-End Holidays etc. (approx. 123 days in a year)
  • Paid Leaves: Annual Paid Leave, Special Paid Leave, Sick Leave, Family Support Leave, Maternity Leave, Childcare Leave, Family Nursing Leave
  • Flexible Work Styles: Flextime, Telework
  • Benefits: Social Insurance, Retirement and Corporate Pension, Employee Stock Ownership Program, etc.

Looking for more opportunities?

Search for other job offers that match your skills and interests.

Similar Jobs for

Global Therapeutic Research Lead (Oligo)

8 matching positions

Grad Pharmacist

You’ve invested a lot of time and energy in your education. Now you want the cha...
Location
Location
United States , Hull
Salary
Salary:
19.75 - 42.00 USD / Hour
https://www.cvshealth.com/ Logo
CVS Health
Expiration Date
September 30, 2026
Flip Icon
Requirements
Requirements
  • PharmD graduate of a U.S. accredited program prior to beginning the Post-Graduate Training Program at CVS Health
  • Ability to obtain required pharmacist licensure within the required timeframe, per state guidelines. Failure to obtain required Pharmacist licensure within 120 days of graduation will result in separation of employment.
  • Must possess, or be in the process of obtaining, valid intern and/or technician licensure as required
  • Regular and predictable attendance, including nights and weekends
  • Ability to complete required training within designated timeframe
  • Attention and Focus: Ability to concentrate on a task over a period of time, Ability to pivot quickly from one task to another to meet patient and business needs, Ability to confirm prescription information and label accuracy, ensuring patient safety
  • Customer Service and Team Orientation: Actively look for ways to help people, and do so in a friendly manner, Notice and understand patients’ reactions, and respond appropriately
  • Communication Skills: Use and understand verbal and written communication to interact with patients and colleagues, Utilize active listening by giving full attention to what others are saying, taking time to understand the points being made, asking questions as appropriate, and not interrupting at inappropriate times
  • Mathematical Reasoning: Ability to use math to solve a problem, such as determining the total number of tablets to dispense, day’s supply, and/or number of full bottles and additional bottles needed to fill a prescription
  • Problem Resolution: Identifying challenging patient or colleague interactions and choosing the best course of action when faced multiple options
Job Responsibility
Job Responsibility
  • Living our purpose by following all company SOPs at each workstation to help our Pharmacists and Technicians manage and improve patient health
  • Following pharmacy workflow procedures at each pharmacy workstation (i.e., production, pick-up, drive-thru, and drop-off) for safe and accurate prescription fulfillment
  • Contributing to positive patient experiences by showing empathy and genuine care: creating heartfelt and personalized moments while serving patients at pick-up, drive-thru, and over the phone
  • keeping patients healthy by offering immunizations and other services at the register and over the phone
  • and demonstrating compassionate care by solving or escalating patient problems
  • Offering to counsel, fielding medical questions, and soliciting information on a patient’s medical history to provide optimal care, when appropriate under the direct supervision of a licensed pharmacist
  • Taking telephonic prescriptions from the prescriber, and calling the prescriber to clarify prescriptions or facilitate medication changes, where allowed by state regulation
  • Maintaining the highest level of self-awareness and providing in-the-moment coaching, training, and mentoring to pharmacy team members while sharing best practices
  • Completing basic inventory activities, as permitted by law, and as directed by the pharmacy leadership team, such as accurately putting away medication deliveries and completing cycle counts, returns-to-stocks, waiting bin inventories, etc.
  • Contributing to a high-performing team, embracing a growth mindset, and being receptive to feedback
What we offer
What we offer
  • dental
  • vision
  • wellness resources
  • employee discounts
  • access to certain voluntary benefits
  • Parttime
Read More
Arrow Right

Director of Product Marketing, AI Commerce

Microsoft AI is building the next generation of AI-powered consumer and commerci...
Location
Location
United States , Redmond
Salary
Salary:
130900.00 - 251900.00 USD / Year
https://www.microsoft.com/ Logo
Microsoft Corporation
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Master's Degree in Marketing, Computer Science, Business or related field AND 4+ years experience in product marketing, business planning, or product strategy OR Bachelor's Degree in Marketing, Computer Science, Business or related field AND 6+ years experience in product marketing, business planning, or product strategy OR equivalent experience.
Job Responsibility
Job Responsibility
  • Lead customer listening strategies to understand evolving shopper, merchant, advertiser, and partner needs, synthesizing research, usage trends, and competitive insights to inform strategy
  • Anticipate market shifts, competitive threats, and whitespace to define Microsoft's leadership position, partnering with field and sales teams to influence roadmap prioritization
  • Define differentiated positioning and compelling value propositions, translating complex AI capabilities into business impact narratives with proof points and use cases
  • Drive consistent storytelling and alignment across Product, Communications, Sales, and Marketing, shaping the broader category narrative for AI-enabled commerce
  • Lead end-to-end GTM strategies—defining launch readiness, success metrics, segmentation, adoption, and growth plans—and orchestrate integrated release motions across launches, tentpole events, and partner activations
  • Equip Sales, Business Development, Marketing, and partner teams with positioning, scenarios, and competitive differentiation through scalable enablement materials, playbooks, and training assets
  • Serve as a strategic partner to Product and Engineering throughout the product lifecycle, influencing roadmap with customer empathy, market insight, and competitive perspective
  • Frame business opportunities, prioritize customer problems, and identify monetization pathways for emerging AI commerce scenarios
  • Collaborate across Microsoft AI, Bing, Copilot, Edge, Advertising, Merchant, and partner ecosystems to align product and GTM priorities
  • Represent Microsoft's AI commerce strategy in customer conversations, executive briefings, and industry events
What we offer
What we offer
  • Benefits and other compensation
  • Fulltime
Read More
Arrow Right

Administrator

Join Our Clients dynamic Team as an Administrator! Are you an organised individu...
Location
Location
United Kingdom , Birmingham
Salary
Salary:
27000.00 - 30000.00 GBP / Year
https://www.office-angels.com Logo
Office Angels
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • At least 1 years' experience in a professional office environment
  • Logical and numerate individual who takes great pride in the accuracy and quality of their work and be prepared to learn
  • Experience in financial services and investing would be desired but is not essential
  • Proven experience in an administrative role-your skills and knowledge are key
  • Excellent organizational and multitasking abilities
  • Strong communication skills, both written and verbal
  • Proficiency in Microsoft Office Suite and other office software (experience with CRM systems is a plus!)
  • A proactive attitude, with a willingness to learn and adapt to new challenges
Job Responsibility
Job Responsibility
  • The ability to work in a fast-paced office environment, delivering high quality work against tight timescales
  • Updating and competent use of the various internal databases and systems
  • Processing and authorising deal instructions to buy, sell and transfer units/shares received by email, post or telephone
  • Placing and confirming portfolio investment trades and liaising with other departments where appropriate
  • Identifying potential issues though analysis of client/agent instructions and liaising with other departments where appropriate
  • Management of electronic dealing systems
  • Updating the register with updates to client or adviser records, including scheduling monthly investment activity (Regular Investment/Withdrawal runs, Adviser Charges)
  • Understanding regulatory requirements affecting the role specifically and financial services in general
  • Allocation of work through scanning and categorisation of mail items into Workflow systems
  • Flexibility in the role to cover other general office duties as required
What we offer
What we offer
  • 25 days annual leave
  • Pension contribution (up to 7.5% of your annual salary)
  • Death in service benefit - up to three times annual salary
  • Private healthcare
  • Income Protection
  • Eye test vouchers
  • Employee assistance programme
  • Length of service benefits
  • Cycle to work
  • Staff training opportunities
  • Fulltime
Read More
Arrow Right

Applications Engineer

We are looking for an experienced Application Developer to join a global product...
Location
Location
United States Of America , Reno
Salary
Salary:
87900.00 - 110000.00 USD / Year
arrow.com Logo
Arrow Electronics
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • 5–7 years of relevant experience with a bachelor’s degree, or equivalent work experience
  • Strong experience with Oracle PL/SQL required
  • Strong technical background supporting applications in a production environment with multiple integrations
  • Hands‑on experience working with integration technologies such as APIs, interfaces, batch jobs, or middleware platforms
  • Proven ability to troubleshoot issues that span multiple systems and teams
  • Comfortable working independently while collaborating closely with global, cross‑functional partners
  • Experience acting as a technical resource or mentor to others
  • Strong communication skills with the ability to explain integration concepts to both technical and non‑technical audiences
  • A quality‑focused mindset with interest in improving system reliability, documentation, and support processes
Job Responsibility
Job Responsibility
  • Design, develop, and support software solutions that operate within a highly integrated enterprise environment
  • Participate across the full software development lifecycle, including design, coding, testing, implementation, auditing, and documentation
  • Provide production support by troubleshooting complex issues across applications, interfaces, and integrated systems
  • Work closely with cross‑functional teams to understand upstream and downstream dependencies, data flows, and system touchpoints
  • Analyze and support integration technologies such as APIs, web services, batch processes, and middleware components
  • Investigate and resolve data and interface issues to ensure accuracy, reliability, and performance across systems
  • Participate in software upgrades, fixes, patches, and vendor‑mandated changes with awareness of integration impacts
  • Contribute to product design, bug verification, beta support, and technical research as needed
  • Share knowledge and provide informal guidance to junior developers and support team members
What we offer
What we offer
  • Medical, Dental, Vision Insurance
  • 401k, With Matching Contributions
  • Paid Time Off (including sick, holiday, vacation, etc.)
  • Health Savings Account (HSA)/Health Reimbursement Account (HRA) Options
  • Growth Opportunities
  • Tuition Reimbursement
  • Short-Term/Long-Term Disability Insurance
  • Climate controlled environment with excellent break room facilities
  • Located in central Reno, near public transportation (RTC Route 56)
  • Fulltime
Read More
Arrow Right

Principal Technical Program Manager - Finance Data & Experiences

Are you passionate about AI, data, and transformative user experiences? Do you b...
Location
Location
United States , Redmond
Salary
Salary:
142800.00 - 274800.00 USD / Year
https://www.microsoft.com/ Logo
Microsoft Corporation
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Bachelor's Degree AND 6+ years experience in engineering, product/technical program management, data analysis, or product development OR equivalent experience
  • 3+ years of experience managing cross-functional and/or cross-team projects
Job Responsibility
Job Responsibility
  • Aligned to organizational strategy and AI-first transformation priorities
  • Lead the integration of product strategy and program execution to deliver unified, persona-driven business solutions across data and AI platforms
  • Partner with engineering and product teams to design scalable architectures that integrate AI capabilities, data platforms, and user experiences
  • Establish and drive a consolidated roadmap spanning multiple programs, balancing near-term delivery with forward-looking platform evolution
  • Create frameworks for persona and scenario-based discovery, translating business needs into prioritized product and program requirements
  • Drive orchestration of complex, cross-functional initiatives, ensuring alignment across Finance, Engineering, and business stakeholders
  • Define decision frameworks for leveraging native Microsoft capabilities versus custom-built solutions
  • Ensure compliance with privacy, security, and responsible AI standards across all solutions
  • Lead experimentation, validation, and feedback loops to continuously improve product experiences and adoption
  • Partner with stakeholders to articulate value, including productivity gains, user adoption, and ROI, and standardize storytelling across programs
  • Fulltime
Read More
Arrow Right

Technical Support Specialist (IT) - Italy Based

Join KPM Analytics as a Technical Support Engineer (IT) in our Trento facility a...
Location
Location
Italy , Pergine – Trento
Salary
Salary:
Not provided
kpmanalytics.com Logo
KPM Analytics
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Minimum 2 years in a technical customer support role
  • BS in Computer Science or Mechatronics, or a related field
  • Strong knowledge of main IT/network infrastructures and network services
  • Strong knowledge of server environment (mainly Microsoft Windows-based)
  • Strong knowledge of SQL and experience with one or more RDBMS (mainly Microsoft SQL)
  • Familiar with scripting languages based on Python, Node.js, and frameworks dedicated to webpage/web application development (mainly Express.js)
  • A good knowledge of English is essential (written and spoken – part of the interview will be conducted in English) at least at the B2 CEFR level
Job Responsibility
Job Responsibility
  • Serve as the primary point of contact for installation, development, and troubleshooting of existing database-based software, with a focus on Machine Vision
  • Analyze and understand customer requests. Provide technical direction and support to customers on the proper use of products through multiple communication channels (phone, email, chat, etc.)
  • Maintaining professional interaction with customers while addressing critical issues is essential
  • Manage Salesforce cases for all Vision Inspection Systems, integrating with support teams worldwide
  • Collaborate with the Technical Support Manager and interface with internal development and software teams (if needed, with the mechanical and electrical engineering teams)
  • Conduct online training for customers (domestic and international)
  • Responsible for continuous learning
  • broadening skill set on KPM products through cross-training activities, utilizing KPM Academy and in-person resources, and employing effective communication skills, to build and maintain strong relationships with KPM customers
What we offer
What we offer
  • A dynamic work environment, with the possibility to work both independently and as part of a team
  • Opportunities to gain increasing independence in customer relations, interacting with a globally distributed customer network
  • Occasional International travel (both within Europe and the rest of the world)
  • Fulltime
Read More
Arrow Right

Senior Mobile Expert

Location
Location
United States , Oklahoma City
Salary
Salary:
20.00 - 29.00 USD / Hour
https://www.t-mobile.com Logo
T-Mobile
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • High School Diploma/GED (Required)
  • Retail: 12+ mos. Neighborhood Mobile Expert (Preferred)
  • Care: Elite Expert, Account Care (Preferred)
  • Care: Elite Expert, Technical Care (Preferred)
  • Communication (Required)
  • Critical Thinking (Required)
  • Customer Service (Required)
  • Multitasking (Required)
  • Product Knowledge (Required)
  • Sales (Required)
Job Responsibility
Job Responsibility
  • Sells appropriate products, features, and services based on customer needs
  • Resolves customer pain points in one interaction utilizing in-store systems and digital tools
  • Completes ongoing training to keep current and develop knowledge and skills to act as SME in all things T-Mobile
  • Consistently leverages digital tools in interactions and onboarding
  • Works collaboratively to build and contribute to a culture of sales and service
What we offer
What we offer
  • Annual stock grant
  • Employee stock purchase plan
  • 401(k)
  • Access to free, year-round money coaches
  • Medical insurance
  • Dental insurance
  • Vision insurance
  • Flexible spending account
  • Paid time off
  • Up to 12 paid holidays
  • Parttime
Read More
Arrow Right

Principal Datacenter Electrical Engineer

Microsoft’s Cloud Operations & Innovation (CO+I) is the engine that powers our c...
Location
Location
United States , Redmond
Salary
Salary:
142800.00 - 274800.00 USD / Year
https://www.microsoft.com/ Logo
Microsoft Corporation
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Doctorate in Electrical Engineering, Computer Engineering, or related field AND 3+ years technical engineering experience OR Master's Degree in Electrical Engineering, Computer Engineering, or related field AND 6+ years technical engineering experience OR Bachelor's Degree in Electrical Engineering, Computer Engineering, or related field AND 8+ years technical engineering experience OR equivalent experience
  • Ability to meet Microsoft, customer and/or government security screening requirements
  • Microsoft Cloud Background Check
Job Responsibility
Job Responsibility
  • Be a thought leader in the development of innovative solutions for our hardware platforms, setting goals, objectives, and outcomes and ensuring that they are met
  • Develop and implement innovative strategies to drive innovation and ideation
  • Provide technical leadership for the system engineering team in developing innovative and scalable products for Microsoft's data centers
  • Identify areas of improvement and develop strategies to address them
  • Define the system requirements, specifications, architectures, and interfaces for the products, ensuring alignment with customer needs, industry standards, and regulatory compliance
  • Be well connected across industry consortia, research, and academic resources
  • Lead with cross-functional teams, such as product management, software engineering, hardware engineering, networking, testing, and validation, to ensure the quality, reliability, and performance of the products
  • Manage the system integration, verification, and validation activities, including conducting prototype testing, field trials, and customer feedback sessions
  • Provide technical guidance, mentoring, and coaching to the system engineering team, fostering a culture of collaboration, innovation, and excellence
  • Fulltime
Read More
Arrow Right