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Flow Cytometry Research Specialist I

United States of America, Rochester 23.06 - 32.29 USD / Hour · Job Posted February 20, 2026
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Job Description

The Research Specialist I plays a critical role in advancing the scientific mission of the Flow Cytometry Resource by providing high-level technical expertise and support to investigators. This position combines hands-on laboratory work with method development, instrument operation, data acquisition, and training responsibilities, and requires the ability to independently execute complex project tasks with minimal supervision. The incumbent serves as a technical mentor to junior staff, contributes to the development and optimization of complex assays, and ensures the consistent delivery of high-quality, reproducible results. Under the direction of the Lab Director, the Research Specialist I drives innovation, supports collaborative research initiatives, and may represent the Resource at regional and national scientific meetings, enhancing the visibility and impact of the program.

Job Responsibility

  • Instrument Operation: setup and maintain flow core instrumentation
  • Operate instruments for investigators as required following SOPs and best practices
  • Operate cell sorters to ensure high-quality reproducible sorting outcomes
  • Method Development, Standardization & Discovery: develop, evaluate, and standardize test methodologies
  • Contribute to innovative method-development efforts
  • Full-Service Investigator Support: sample preparation and staining, data acquisition, and preliminary data analysis
  • Experimental Design & Protocol Troubleshooting: Provides expert guidance and troubleshooting for investigators on experimental design, assay optimization, and protocol development
  • Staff Training, Mentorship & Oversight: Trains junior laboratory staff
  • Supports junior staff in developing their own projects and professional growth
  • Instruction & Technical Guidance: Teaches laboratory techniques, instrumentation procedures, and best practices
  • Offers technical counseling, assists with specialized research needs, and helps investigators resolve complex methodological challenges

Requirements

  • Bachelor’s degree in Biological Sciences, Immunology, Biomedical Engineering, or a related field
  • Minimum of 1 year of hands-on flow cytometry experience in a research, clinical, or core facility environment
  • Strong working knowledge of flow cytometry theory, fluorochromes, compensation, panel design, and quality control
  • Demonstrated ability to independently troubleshoot technical and experimental issues
  • Excellent communication skills, including the ability to teach and mentor diverse trainees
  • Strong organizational and time-management skills, with the ability to manage multiple projects simultaneously
  • Proficiency with flow cytometry software (e.g., FACSDiva, FlowJo, SpectroFlo, FCS Express)
  • Ability to follow and develop SOPs, maintain accurate records, and uphold laboratory best practices

Nice to have

  • Masters degree (preferred)
  • 3 years experience of flow cytometry experience (preferred)
  • SCYM in cytometry

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