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ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development. Reporting to the Director of Feasibility, the Feasibility Principal provides strategic, study-level feasibility leadership within the Patient and Site Engagement (PSE) team, supporting the acceleration of clinical studies across rare disease programs. This role leads feasibility strategy and analysis for assigned studies, translating complex operational and enrollment data into clear, data-driven recommendations that inform study planning and enrollment decisions. Working cross-functionally, the Feasibility Principal also contributes to continuous improvement efforts and mentors junior team members, while operating effectively in a fast-paced, dynamic environment.
Job Responsibility
Lead feasibility strategy and execution at the study level, supporting trial optimization and delivery of key milestones, while ensuring alignment with broader program objectives and feasibility standards
Synthesize and analyze feasibility, operational, and enrollment data from multiple internal and external sources to develop a comprehensive understanding of therapeutic areas, standard of care, disease progression, patient and site profiles, and the competitive landscape
Evaluate the clinical trial landscape and apply advanced data mining and analytical approaches, including complex enrollment modeling and forecasting, to translate findings into data-driven enrollment assumptions, risk assessments, and strategic recommendations
Operate effectively in a fast-paced, dynamic study environment, rapidly assessing changing inputs, reprioritizing work, and adjusting feasibility approaches to meet tight timelines
Apply strong time management and prioritization skills to balance multiple studies and last-minute requests while maintaining analytical rigor and clear communication
Serve as a key feasibility partner with cross-functional study teams, clearly communicating insights, assumptions, risks, and recommendations to support study planning, site selection, and enrollment strategy decisions
Lead and deliver data-driven presentations to cross-functional teams and governance forums, including presenting analyses and responding to questions from senior leadership, as appropriate
Mentor and provide guidance to junior feasibility team members, supporting development of analytical skills, best practices, and consistency in deliverables
Apply strong operational judgment and clinical trial expertise to proactively identify challenges, anticipate risks, and drive solutions
Contribute to continuous improvement of feasibility processes, tools, and best practices by sharing insights and lessons learned
Requirements
Bachelor's degree in a scientific or allied health field (or equivalent industry experience), with 7+ years of progressive experience in clinical research, feasibility, clinical operations, or study startup within a sponsor or CRO environment
Minimum of 5 years of hands-on operational feasibility experience supporting complex studies or programs
Demonstrated experience leading feasibility strategy for complex studies or programs, with a proven track record of influencing decisions related to site selection, enrollment strategy, and study acceleration
Experience working across multiple therapeutic areas or late-phase programs with increasing strategic accountability
Demonstrated ability to analyze, synthesize, and interpret complex feasibility, operational, and enrollment data, translating findings into clear insights and actionable recommendations
Advanced proficiency in Excel and other data-driven analysis tools, including experience in structuring, analyzing, and presenting data for feasibility assessments, benchmarking, and enrollment forecasting
Strong verbal and written communication skills, with the ability to clearly present complex, data-driven analyses to diverse stakeholders
Demonstrated critical thinking and solution-oriented, creative problem-solving skills
What we offer
Various annual leave entitlements
A range of health insurance offerings to suit you and your family’s needs
Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead
Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being
Life assurance
Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others