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The Executive Director, Global Health Economics and Outcomes Research (HEOR), will lead the global HEOR function, with a portfolio comprising both mature, marketed products and late-stage assets in pre-launch. This role is accountable for defining and executing integrated global evidence and value strategies across the full product lifecycle, from early development through post-launch optimization.
Job Responsibility:
Define and own the global HEOR strategy across marketed products and pipeline assets, aligned with corporate and portfolio priorities
Provide strategic leadership and direction to a global HEOR team, fostering scientific excellence and operational rigor
Manage external vendors, academic partnerships, and research collaborations to deliver high-quality evidence efficiently
Lead early value and evidence planning for late-stage and pre-launch assets, including development of global value stories and integrated evidence plans
Partner with Clinical Development to ensure trial designs, endpoints, and comparators address future HTA and payer requirements, particularly in rare diseases
Inform Target Product Profiles (TPPs) and access-relevant decision-making during development
Support global and regional Market Access teams with HEOR inputs for launch planning, pricing strategy, and reimbursement submissions
Oversee development of global value dossiers, cost-effectiveness models, budget impact analyses, and AMCP/HTA submissions
Anticipate and address access challenges in key markets, including evidence uncertainty common in rare and ultra-rare indications
Drive post-launch evidence generation, including real-world evidence (RWE), registries, and long-term outcomes studies, to support label expansions, re-assessments, and sustained reimbursement
Optimize value demonstration for mature brands through updated economic models, new endpoints, and evolving payer needs
Monitor changes in global HTA and payer landscapes and proactively adapt evidence strategies
Ensure integration of patient-reported outcomes (PROs), quality-of-life, caregiver burden, and disease burden data into global evidence strategies
Collaborate closely with Medical Affairs on publications, scientific exchange, and congress strategy
Partner with Patient Advocacy and external stakeholders to embed the patient voice in value narratives
Oversee HEOR publications, abstracts, and presentations at major international congresses (e.g., ISPOR, HTAi, DIA)
Represent the company in external scientific, policy, and payer-related forums
Ensure all HEOR activities comply with global regulatory, ethical, and scientific standards
Requirements:
PhD, DrPH, PharmD, MD, or equivalent advanced degree in Health Economics, Outcomes Research, Public Health, Epidemiology, Health Policy, or related discipline
Fluent in English
Minimum 15+ years of commercial experience in the pharmaceutical industry
Minimum of 10+ years of HEOR experience in pharmaceutical or biotechnology companies, with significant exposure to rare diseases and global roles
Demonstrated success supporting global launches and pre-launch assets, as well as lifecycle management of marketed products
Proven experience engaging with HTA bodies and payer stakeholders across major markets (US, EU, UK, Japan)
Experience leading multicultural teams
With experience of specialty care products in highly competitive markets
Proven track record of marketing across multiple stages of a products life cycle
Successful Global launch experience in specialty and/or rare disease, preferably in the specific therapeutic area
Strong leadership skills and business acumen
Demonstrated agility, accountability, sense of urgency and team spirit
Capability to embark and enroll cross functional stakeholders at all levels of the organizations
Ability to build strong relationships across cultures, backgrounds and functions
Can manage complex situations and demonstrated ability to make decisions
Strong planning and project management skills – can and has successfully driven projects involving several departments and functions
Ability to convey complex information succinctly & simply (including verbal, written and in presentations)
Resilience and openness to change
Complies with Company guidelines and country/industry standards on ethics and compliance and acts as a role model for ethical behavior
Nice to have:
Experience in rare diseases market would be a plus