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Executive Director, Global Health Economics and Outcomes Research

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BioMarin Pharmaceutical

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Location:
United Kingdom , London

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Contract Type:
Not provided

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Salary:

Not provided

Job Description:

The Executive Director, Global Health Economics and Outcomes Research (HEOR), will lead the global HEOR function, with a portfolio comprising both mature, marketed products and late-stage assets in pre-launch. This role is accountable for defining and executing integrated global evidence and value strategies across the full product lifecycle, from early development through post-launch optimization.

Job Responsibility:

  • Define and own the global HEOR strategy across marketed products and pipeline assets, aligned with corporate and portfolio priorities
  • Provide strategic leadership and direction to a global HEOR team, fostering scientific excellence and operational rigor
  • Manage external vendors, academic partnerships, and research collaborations to deliver high-quality evidence efficiently
  • Lead early value and evidence planning for late-stage and pre-launch assets, including development of global value stories and integrated evidence plans
  • Partner with Clinical Development to ensure trial designs, endpoints, and comparators address future HTA and payer requirements, particularly in rare diseases
  • Inform Target Product Profiles (TPPs) and access-relevant decision-making during development
  • Support global and regional Market Access teams with HEOR inputs for launch planning, pricing strategy, and reimbursement submissions
  • Oversee development of global value dossiers, cost-effectiveness models, budget impact analyses, and AMCP/HTA submissions
  • Anticipate and address access challenges in key markets, including evidence uncertainty common in rare and ultra-rare indications
  • Drive post-launch evidence generation, including real-world evidence (RWE), registries, and long-term outcomes studies, to support label expansions, re-assessments, and sustained reimbursement
  • Optimize value demonstration for mature brands through updated economic models, new endpoints, and evolving payer needs
  • Monitor changes in global HTA and payer landscapes and proactively adapt evidence strategies
  • Ensure integration of patient-reported outcomes (PROs), quality-of-life, caregiver burden, and disease burden data into global evidence strategies
  • Collaborate closely with Medical Affairs on publications, scientific exchange, and congress strategy
  • Partner with Patient Advocacy and external stakeholders to embed the patient voice in value narratives
  • Oversee HEOR publications, abstracts, and presentations at major international congresses (e.g., ISPOR, HTAi, DIA)
  • Represent the company in external scientific, policy, and payer-related forums
  • Ensure all HEOR activities comply with global regulatory, ethical, and scientific standards

Requirements:

  • PhD, DrPH, PharmD, MD, or equivalent advanced degree in Health Economics, Outcomes Research, Public Health, Epidemiology, Health Policy, or related discipline
  • Fluent in English
  • Minimum 15+ years of commercial experience in the pharmaceutical industry
  • Minimum of 10+ years of HEOR experience in pharmaceutical or biotechnology companies, with significant exposure to rare diseases and global roles
  • Demonstrated success supporting global launches and pre-launch assets, as well as lifecycle management of marketed products
  • Proven experience engaging with HTA bodies and payer stakeholders across major markets (US, EU, UK, Japan)
  • Experience leading multicultural teams
  • With experience of specialty care products in highly competitive markets
  • Proven track record of marketing across multiple stages of a products life cycle
  • Successful Global launch experience in specialty and/or rare disease, preferably in the specific therapeutic area
  • Strong leadership skills and business acumen
  • Demonstrated agility, accountability, sense of urgency and team spirit
  • Capability to embark and enroll cross functional stakeholders at all levels of the organizations
  • Ability to build strong relationships across cultures, backgrounds and functions
  • Can manage complex situations and demonstrated ability to make decisions
  • Strong planning and project management skills – can and has successfully driven projects involving several departments and functions
  • Ability to convey complex information succinctly & simply (including verbal, written and in presentations)
  • Resilience and openness to change
  • Complies with Company guidelines and country/industry standards on ethics and compliance and acts as a role model for ethical behavior

Nice to have:

Experience in rare diseases market would be a plus

Additional Information:

Job Posted:
February 14, 2026

Work Type:
Hybrid work
Job Link Share:

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