Downstream System Owner Job at Amgen (Thousand Oaks)

Sr. Engineer - Reliability System Owner (Drug Substance Ops)

Join Amgen's Mission of Serving Patients. At Amgen, if you feel like you're part...

Location

United States of America , Juncos

Salary:

Not provided

Amgen

Expiration Date

Until further notice

Requirements

Doctorate degree in Engineering
Or Master's degree in Engineering and 2 years of Engineering and/or Mfg Support experience
Or Bachelor's degree in Engineering and 4 years of Engineering and/or Mfg Support experience
Experience in equipment reliability, lifecycle management, and performance optimization
Knowledge of reliability engineering tools and techniques, including FMEA (Failure Modes and Effects Analysis) and predictive maintenance strategies
Proficiency in structured problem‑solving methodologies, such as DMAIC, and root cause analysis tools including Fishbone diagrams and related techniques
Proficiency in statistical analysis, Design of Experiments (DOE), and data‑driven decision‑making
Knowledge of Drug Substance Downstream operations and equipment, including chromatography columns, buffer preparation systems, analytical systems, and bioreactors (with strong emphasis on downstream processes)
Demonstrated ability to lead and collaborate with multi‑functional teams to resolve system‑level technical challenges
Skilled in translating complex technical data into clear, actionable insights for diverse stakeholders

Job Responsibility

Own the reliability, performance, and lifecycle of critical systems and equipment
Act as System Owner for assigned equipment and systems, maintaining full technical accountability for performance, reliability, and validated state
Investigate unexpected system and equipment failures, performing root cause analysis and leading the development and execution of corrective and preventive actions
Define, own, and continuously optimize equipment reliability strategies, including maintenance strategy, risk mitigation, and lifecycle management
Develop, implement, and improve Preventive Maintenance (PM) strategies and job plans, optimizing maintenance frequencies based on data, failure modes, and reliability analysis
Lead efforts to optimize maintenance intervals through data driven optimization while ensuring equipment reliability, compliance, and validation integrity
Ensure availability and management of spare parts, including identification of critical spares, inventory monitoring (stock / non‑stock), and coordination with technical and maintenance teams
Maintain equipment in a validated state, ensuring data integrity, system compliance, and alignment with cGMP and regulatory expectations
Serve as technical owner for equipment improvement and upgrade projects, including reliability enhancements and performance optimization initiatives
Support New Equipment Introduction (NEI/NPI) activities, ensuring equipment meets user requirements, specifications, validation needs, and operational readiness

What we offer

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental & vision coverage, and life & disability insurance
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans and an annual site shutdown
Flexible work models, including remote work arrangements, where possible

Fulltime

Design System Technical Product Owner

Join Barclays as a Design System Technical Product Owner and play a pivotal role...

Location

United Kingdom , Greater Manchester; Knutsford; Northampton

Salary:

Not provided

Barclays

Expiration Date

Until further notice

Requirements

Proven ability to influence diverse stakeholders and drive large-scale adoption initiatives
Strong ownership of Agile and Scrum practices, including backlog management, roadmap planning, and product strategy definition
Deep experience with enterprise design systems, including component-based architecture, design tokens, design-to-code workflows, and accessibility standards
Demonstrated expertise in release and versioning strategies, including semantic versioning and coordination of cross-platform releases to minimise downstream impact
Effective cross-functional collaboration with design, engineering, and platform teams to deliver cohesive solutions

Job Responsibility

Drive the vision, value, and adoption of the design system across a multidisciplinary team of 30+ specialists
Define and communicate a clear product strategy
Align stakeholders around shared goals
Own and prioritise the backlog to ensure delivery of high-impact, user-centric capabilities
Lead agile delivery excellence through strong facilitation, continuous improvement, and effective team collaboration
Enable the creation of consistent, accessible, and scalable digital experiences across Barclays’ ecosystem

What we offer

Competitive holiday allowance
Life assurance
Private medical care
Pension contribution

Fulltime

New

Supply Chain Sr Manager - Data Governance, Stewardship & PMD

Join Amgen’s Mission of Serving Patients. At Amgen, if you feel like you’re part...

Location

United States , Charlotte

Salary:

134061.15 - 181376.85 USD / Year

Amgen

Expiration Date

Until further notice

Requirements

High school diploma / GED and 12 years of Supply Chain, Operations, Data Management, Manufacturing, Business Process, or related experience OR Associate’s degree and 10 years of Supply Chain, Operations, Data Management, Manufacturing, Business Process, or related experience OR Bachelor’s degree and 6 years of Supply Chain, Operations, Data Management, Manufacturing, Business Process, or related experience OR Master’s degree and 4 years of Supply Chain, Operations, Data Management, Manufacturing, Business Process, or related experience OR Doctorate degree and 2 years of Supply Chain, Operations, Data Management, Manufacturing, Business Process, or related experience

Job Responsibility

Lead data stewardship activities across Operations, ensuring timely, accurate, and compliant execution
Serve as the primary business lead for Production Master Data, including oversight of data standards, data quality, issue resolution, and lifecycle management
Establish and maintain data governance practices, controls, and documentation to support operational readiness and business continuity
Partner with business and technical teams to define data ownership, accountability, validation rules, and escalation pathways
Ensure adherence to applicable policies, procedures, regulatory expectations, and internal controls related to master data management
Oversee and coordinate data load activities supporting operational processes across the Plan-to-Stock stream of work
Lead planning, readiness, validation, defect resolution, and post-load support for data migration, transformation, and ongoing maintenance activities
Collaborate with IT, business process owners, and functional SMEs to ensure data load requirements are understood, tested, and successfully executed
Monitor data load performance, identify risks or gaps, and drive timely corrective actions
Act as the functional lead for Production Master Data across supply chain and operations processes

What we offer

Health and welfare plans
Financial plans with opportunities to save towards retirement or other goals
Work/life balance
Career development opportunities
Retirement and Savings Plan with generous company contributions
Group medical, dental and vision coverage
Life and disability insurance
Flexible spending accounts
Discretionary annual bonus program
Stock-based long-term incentives

Fulltime

New

Senior Billing Systems & Operations Analyst

As the Senior Billing Systems & Operations Analyst, you will administer Qualia's...

Location

United States , Austin

Salary:

Not provided

Qualia

Expiration Date

Until further notice

Requirements

Quote-to-Cash Expertise: 3+ years of hands-on experience working with billing tools, CPQ platforms, Salesforce, or ERP systems across the quote-to-cash lifecycle
Billing/CPQ Platform Depth: Direct experience administering or deeply configuring billing platforms, CPQ tools (e.g., Salesforce CPQ, DealHub, Ordway, Zuora, Chargebee), or similar systems
An Owner's Mentality
A Problem-Solving Mindset
An Eye for Operations
Technical Aptitude
Project Management Expertise
A Drive to Execute
A minimum of 5 years of progressively increasing responsibility in billing operations, deal desk, revenue operations, or strategic finance/finance ops, with demonstrated experience in platform administration and process optimization

Job Responsibility

Billing Systems Administration: Own all aspects of our billing platform's configuration, optimization, and expansion. Build and maintain monitoring and alerting that surfaces data quality issues before they reach customers. Drive process standardization alongside Finance and Deal Desk to reduce billing complexity and manual intervention. Continuously refine the system to improve accuracy, automation, and reliability across the invoicing and billing lifecycle
Cross-Functional Partnership & Advisory: Serve as the connective tissue between finance, product, engineering, and GTM teams on all billing-related matters. Advise on how new products, discounting frameworks, payment structures, and bookings policies will function within the billing architecture. Proactively flag risks when business decisions could create downstream complexity. Own the vendor relationship, holding them accountable to SLAs and advocating for Qualia's needs on the roadmap
Billing Operations Documentation: Serve as the go-to owner of all things associated with systematic financial operations. Work with the billing team to build comprehensive operational documentation—runbooks, configuration guides, and process maps—so that billing system knowledge is institutional, not individual. Ensure billing data flows accurately across connected systems and that every team with a dependency on billing data has the visibility they need
Leverage AI for Operational Efficiency: Qualia is an AI first company. As a systems administrator, you will be charged with leveraging LLMs and AI to drive insights and operational efficiency for our front line collections and billing teams

What we offer

Comprehensive health plans
401k program
Commuter benefits
Professional development
Parental leave
Flexible time off policy
Robust online onboarding program
Biweekly all hands meetings
Internal virtual events

Fulltime

New

Systems and Data Analyst

At Boeing, we innovate and collaborate to make the world a better place. We’re c...

Location

United States , Everett; Seattle; Seal Beach; San Antonio; Hazelwood; Mesa; Renton; Dallas

Salary:

96050.00 - 173650.00 USD / Year

Boeing

Expiration Date

June 24, 2026

Requirements

3+ years of experience with Transportation Management, Transportation Data Analytics and Route Planning experience
Experience with Transportation Management System (TMS)
Experience with Transportation Management Systems deployment
Experience with the Software Development Lifecycle (SDLC)
Experience with collecting, organizing, synthesizing, and analyzing data, summarizing findings, developing conclusions and recommendations from appropriate data sources
Experience working within Agile project frameworks

Job Responsibility

Lead efforts to define and document detailed business requirements
Learn each business unit’s logistics and transportation flows, processes, and products
Facilitate regular requirements‑gathering and design sessions with product owners and users, translating requirements into system designs
Articulate how architecture, design, implementation, testing, and deployment interact to enable effective solutions
Configure the BlueYonder Transportation Management System (TMS)
Apply domain knowledge of Transportation Management, Transportation Planning & Consolidation, load building, shipment tendering, tariffs/rating, track & trace/visibility, financials and audit, fleet management, transportation modeling, carrier collaboration, and master data
Integrate TMS with upstream and downstream systems, including Enterprise Resource Planning systems (ERPs), global trade, dangerous goods, freight payment, and visibility platforms
Negotiate solutions that satisfy requirements and deliver business value while maintaining consistency and security standards
Identify process improvement opportunities by reviewing existing processes and data
Develop and execute tests to validate system functionality against specifications

What we offer

health insurance
flexible spending accounts
health savings accounts
retirement savings plans
life and disability insurance programs
paid and unpaid time away from work
generous company match to your 401(k)
industry-leading tuition assistance program pays your institution directly
fertility, adoption, and surrogacy benefits
up to $10,000 gift match when you support your favorite nonprofit organizations

Fulltime

!

New

Security Data Engineer

We are looking for a Security Data Engineer to join our team in Costa Mesa, Cali...

Location

United States , Costa Mesa

Salary:

Not provided

Robert Half

Expiration Date

Until further notice

Requirements

Experience building and supporting data pipelines in a data lake or large-scale data engineering environment
Strong programming skills in Python and hands-on experience with Apache Spark, Apache Hadoop, Apache Kafka, and ETL development
Practical knowledge of Amazon Web Services (AWS) and infrastructure automation tools such as AWS CDK and Infrastructure as Code frameworks
Experience maintaining pipeline reliability, troubleshooting ingestion issues, and improving operational stability in production environments
Ability to work directly with internal stakeholders to locate source data, obtain access, and move integrations forward
Familiarity with data analysis and data cleaning techniques that improve downstream usability and trust in datasets
Exposure to CI/CD practices and deployment automation for data engineering workflows
Additional programming experience in Rust or Go is preferred

Job Responsibility

Take ownership of the data ingestion layer for an existing data lake, ensuring steady performance and dependable delivery of incoming datasets
Reduce a defined backlog of pipeline work during the first 90 days by building and activating prioritized ingestion workflows
Assume responsibility for pipeline components transitioned from the lead engineer and continue their operational support without disrupting established foundations
Support and improve current ETL processes by monitoring health, resolving failures, and extending coverage where needed
Integrate new source systems, including platforms such as Rippling and Workday, into the broader data ecosystem
Coordinate with internal application and system owners to identify data sources, secure appropriate access, and obtain logs or source records required for ingestion
Apply data cleaning and analysis practices to improve data quality and maintain consistency across inbound datasets
Contribute to infrastructure and deployment workflows using AWS, AWS CDK, Infrastructure as Code, and CI/CD practices to support scalable pipeline operations

What we offer

Medical, vision, dental, and life and disability insurance
Eligibility to enroll in company 401(k) plan
Free online training

New

IT Business Lead Analyst

Citibank, N.A. seeks an IT Business Lead Analyst for its Tampa, Florida location...

Location

United States , Tampa

Salary:

142100.00 - 159580.00 USD / Year

Citi

Expiration Date

July 24, 2026

Requirements

Requires a Bachelor’s degree, or foreign equivalent, in Business Administration, Finance, Analytics, Engineering (any) or related field and 6 years of progressive, post-baccalaureate experience as a Business Analyst, Consultant, Project Manager, or related position managing capital markets/Risk Weighted Asset projects for the financial services industry. 6 years of experience must include: Financial Risk management (Market and Credit Risk)
IT Project Management
Business Analytics
Data analysis
Basel and Geo specific regulatory requirements
Understanding of Capital Markets Regulatory Landscape and Most recent Regulations (FRTB)
Software development methodologies: Agile and Scrum
Project management tools: JIRA, Confluence, and Microsoft PowerPoint
and Data analysis reporting tools: Microsoft Excel. Must also have 3 years of experience with User Acceptance Testing and SQL.

Job Responsibility

Plan, initiate, and manage information technology (IT) projects supporting regulatory reporting programs for Risk Weighted Assets (RWA) function of Market Risk team
Serve as liaison between business and technical aspects of projects
Analyze business performance to drive business planning, plan project stages and assess business implications for each stage
Lead finance and RWA initiatives, and represent Market Risk team in face-to-face meeting with Financial Capital Planning group
Analyze RWA components of market risk, including de-minimis risk, standard specific market risk and trading book securitization, to understand changes and analytics required to be implemented for reporting
Leverage expertise in Basel and local regulatory requirements, including rules under Prudential Regulatory Authority and Monetary Authority of Singapore, to conduct requirement elicitation session with finance and risk stakeholders and to coordinate with development team for implementation of these requirements
Keep an inventory of new project requests under assigned asset class, and engage business and finance capital planning stakeholders for new project initiatives discussion
Plan, coordinate and conduct User Acceptance Testing (UAT)
Use JIRA tool for requirement elicitation and UAT approval and implementation
Obtain approvals on requirements documents, test plans and test results from business owners and stakeholders

What we offer

Medical, dental & vision coverage
401(k)
Life, accident, and disability insurance
Wellness programs
Paid time off packages, including planned time off (vacation), unplanned time off (sick leave), and paid holidays

Senior CRM Process Owner

The CRM and Business Excellence team in Zalando's Partner Platform Business is l...

Location

Germany , Berlin

Salary:

Not provided

Zalando

Expiration Date

Until further notice

Requirements

5+ years in Salesforce Platform Development, experience building standardized intervention playbooks for partner performance and monetization
Proven track record of implementing Salesforce Flows, configurations and AI-driven automation via Agentforce or Einstein to drive productivity
Required Salesforce Certified Administrator and Platform App Builder
Sales or Service Cloud Consultant certifications are highly preferred
Strong experience in Agile/Scrum environments, proficient in managing backlogs in Jira and mapping processes in Signavio/Other process mapping tools
Exceptional ability to influence senior leadership by translating technical AI capabilities into clear business value and operational ROI
Experience in CRMA (Salesforce CRM Analytics) will be highly appreciated as we look to drive deeper data-driven insights for our partner ecosystem

Job Responsibility

Lead the design and refinement of best-in-class workflows for the entire partner lifecycle, including acquisition, contract management, onboarding, and Service Cloud
Proactively identify and replace 'offline' processes with integrated Salesforce solutions to ensure a single source of truth
Evaluate systemic impact: Assess how new features or process changes affect downstream systems
Drive AI-Enabled Innovation: Oversee the functional implementation of cutting-edge Salesforce technologies
Design intuitive workflows and Salesforce configurations that prioritize user experience and data integrity
Standardize Documentation: Map business processes using industry standards
Maintain Data Integrity: Oversee data management practices
Bridge the Business-Tech Gap: Act as the primary liaison between non-technical business units and engineering teams
Coordinate Cross-Functional Releases: Ensure successful go-live strategies
Own Quality Assurance: Lead User Acceptance Testing (UAT)

What we offer

Employee shares program
40% off fashion and beauty products sold and shipped by Zalando, 30% off Zalando Lounge, discounts from external partners
2 paid volunteering days a year
Hybrid working model with up to 60% remote per week
Work from abroad for up to 30 working days a year
27 days of vacation a year to start
Relocation assistance available (subject to prior agreement)
Family services, including counseling and support
Health and wellbeing options (including Gympass)
Mental health support and coaching available

Fulltime

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Downstream System Owner

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