CrawlJobs Logo

Director, Portfolio Decision Sciences

us.gsk.com Logo

GSK

Location Icon

Location:
United Kingdom; United States , London ▼

Category Icon
Category:
Research and Development

Job Type Icon

Contract Type:
Not provided

Salary Icon

Salary:

Not provided
Save Job
Save Icon
Apply Position

Job Description:

GSK is seeking a highly skilled and visionary Director, Portfolio Decision Sciences to partner with the Head, Portfolio Decision Sciences, Oncology in supporting GSK’s Oncology and broader Pharmaceutical portfolio across the entire R&D lifecycle – from preclinical research through late‑stage clinical development. In this influential role, you will work directly with project teams and governance boards to evaluate investment opportunities in areas of high uncertainty and limited data. You will play a pivotal part in guiding technical progression and investment decisions through systematic risk assessment, probabilistic evaluation, and rigorous economic analysis (e.g., ROI, NPV). Your insights will inform key decision‑making bodies including the Portfolio Investment Board (PIB), Development Review Board (DRB) and Research Unit Investment Boards. You will shape strategically differentiated options, drive challenging conversations with senior leaders, and leverage cutting‑edge data and technology trends to enable high‑quality portfolio decision making. The ideal candidate is an intellectually curious portfolio expert with deep R&D experience, a passion for innovation, and the ability to navigate and influence broadly across the Oncology and R&D ecosystems at GSK.

Job Responsibility:

  • Guiding project teams across the R&D lifecycle (including BD opportunities) using strategic decision frameworks, probability‑of‑success elicitation, and economic evaluations (ROI, NPV), facilitating decision making and generating project‑ and portfolio‑level insights
  • Delivering objective project assessments for R&D investment decisions at Research Unit governance bodies, and the Portfolio Investment Board (PIB)
  • Providing clear, rigorous recommendations to governance chairs based on detailed value‑risk analyses, option evaluations, resource considerations, and risk‑discharge points
  • Leading portfolio‑ or indication‑level assessments to inform senior leaders on prioritisation decisions across scientific, commercial, operational, strategic and financial dimensions
  • Supporting the biannual dynamic Portfolio Review (dPR) for Oncology, ensuring refreshed project assessments and surfacing emerging investment opportunities
  • Collaborating across finance, portfolio management, strategy, operations, and Research Units to recommend short‑ and long‑term focus areas and enable optimal resource deployment
  • Driving portfolio management excellence by monitoring the external environment, evaluating innovative portfolio approaches, and proposing use cases applicable to GSK
  • Enhancing the development and deployment of advanced analytics, including AI and machine learning, to elevate decision‑making quality across teams and senior leadership

Requirements:

  • Bachelor’s degree in Science or Business
  • PhD, MD, or advanced scientific/decision sciences degree preferred
  • Demonstrated experience in pharmaceutical, healthcare, or related industries
  • Strong understanding of R&D processes, ideally with experience supporting or leading drug‑development teams
  • Proven track record of independently delivering complex projects
  • Experience navigating cross‑functional teams and enabling change
  • High learning agility
  • ability to facilitate complex scientific, technical, value, and resourcing discussions
  • Ability to translate detailed scientific and technical insights into concise, impactful recommendations
  • Strong relationship‑building skills to become a trusted strategic partner to project teams and senior leaders
  • Ability to manage multiple projects, priorities, and fast‑paced decision cycles

Additional Information:

Job Posted:
January 31, 2026

Expiration:
February 10, 2026

Employment Type:
Fulltime
Icon
GSK - All Job Offers
Job Link Share:
Copy Link Icon
Facebook Icon Twitter Icon LinkedIn Icon

Looking for more opportunities? Search for other job offers that match your skills and interests.

Briefcase Icon

Similar Jobs for Director, Portfolio Decision Sciences

Senior Audit Manager – AI Technology, Cyber, Data and GenAI Engineering

The Senior Audit Manager is within the AI Technology, Cyber, Data and GenAI Engi...
Location
Location
India , Mumbai
Salary
Salary:
Not provided
https://www.citi.com/ Logo
Citi
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Previous experience in a related role
  • Sound understanding in AI Technology, Cyber, Data and GenAI Engineering
  • Understanding of GenAI security, data and operational architecture
  • Understanding of financial services regulations and how they intersect with AI/GenAI e.g. conduct risk, operational resilience, data protection, algorithmic trading, AML/KYC, consumer protection
  • Related certifications such as Certified Information Systems (CISA), Certified Internal Auditor (CIA), Certified in Risk and Information Systems (CRISC) or similar
  • Demonstrated successful experience in business, functional and people management
  • Proven ability to execute concurrently on a portfolio of high quality deliverables according to strict timetables
  • Demonstrated ability to implement continuous improvement and innovation in audit tools and techniques
  • Consistently demonstrates clear and concise written and verbal communication
  • Demonstrated ability to remain unbiased in a diverse working environment
Job Responsibility
Job Responsibility
  • Deliver audit reports, Internal Audit and Regulatory issue validation and business monitoring and governance committee reports relating to AI Technology, Cyber, Data and GenAI Engineering
  • Act as a trusted subject matter experts on AI Technology, Cyber, Data and GenAI Engineering across the IA team
  • Oversight of portfolios within the AI Technology, Cyber, Data and GenAI Engineering team including stakeholder engagement, assessment of key emerging and inherent risks, etc
  • Participate in business initiatives and pro-actively advise and assist the business on change initiatives
  • Implement integrated auditing concepts and technology, and follow trends in the Audit field and adapt them for the Audit function
  • Identify solutions for a variety of complex and unique control issues, utilizing complex judgement and sophisticated analytical thought
  • Analyse report findings, and recommend interventions where needed, proposing creative and pragmatic solutions to risk and control issues
  • Partner with Directors and Managing Directors to develop approaches for addressing broader corporate emerging issues
  • Appropriately assess risk when business decisions are made, demonstrating particular consideration for the firm's reputation and safeguarding Citigroup, its clients and assets, by driving compliance with applicable laws, rules and regulations, adhering to Policy, applying sound ethical judgment regarding personal behaviour, conduct and business practices, and escalating, managing and reporting control issues with transparency, as well as effectively supervise the activity of others and create accountability with those who fail to maintain these standards
  • Fulltime
Read More
Arrow Right

Senior Audit Manager – AI Non-model Objects

The Senior Audit Manager is within the AI Non-model Objects team and is a senior...
Location
Location
India , Mumbai
Salary
Salary:
Not provided
https://www.citi.com/ Logo
Citi
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Previous experience in a related role
  • Sound understanding in model audit, validation, or model risk management within financial services
  • Understanding of financial services regulations and how they intersect with AI/GenAI e.g. conduct risk, operational resilience, data protection, algorithmic trading, AML/KYC, consumer protection
  • Related certifications such as Certified Information Systems (CISA), Certified Internal Auditor (CIA), Certified in Risk and Information Systems (CRISC) or similar. AI-related certifications are a plus
  • Demonstrated successful experience in business, functional and people management
  • Proven ability to execute concurrently on a portfolio of high quality deliverables according to strict timetables
  • Demonstrated ability to implement continuous improvement and innovation in audit tools and techniques
  • Consistently demonstrates clear and concise written and verbal communication
  • Demonstrated ability to remain unbiased in a diverse working environment
  • Effective negotiation skills
Job Responsibility
Job Responsibility
  • Deliver audit reports, Internal Audit and Regulatory issue validation and business monitoring and governance committee reports relating to AI model development, validation and deployment
  • Act as a trusted subject matter experts on AI Model risks and controls across the IA team
  • Oversight of portfolios within the AI Non-model Objects team including stakeholder engagement, assessment of key emerging and inherent risks, etc.
  • Participate in business initiatives and pro-actively advise and assist the business on change initiatives
  • Implement integrated auditing concepts and technology, and follow trends in the Audit field and adapt them for the Audit function
  • Identify solutions for a variety of complex and unique control issues, utilizing complex judgement and sophisticated analytical thought
  • Analyze report findings, and recommend interventions where needed, proposing creative and pragmatic solutions to risk and control issues
  • Partner with Directors and Managing Directors to develop approaches for addressing broader corporate emerging issues
  • Appropriately assess risk when business decisions are made, demonstrating particular consideration for the firm's reputation and safeguarding Citigroup, its clients and assets, by driving compliance with applicable laws, rules and regulations, adhering to Policy, applying sound ethical judgment regarding personal behavior, conduct and business practices, and escalating, managing and reporting control issues with transparency, as well as effectively supervise the activity of others and create accountability with those who fail to maintain these standards
  • Fulltime
Read More
Arrow Right

Senior Audit Manager – AI Non-model Objects – Senior Vice President

The Senior Audit Manager is within the AI Non-model Objects team and is a senior...
Location
Location
United Kingdom , London
Salary
Salary:
Not provided
https://www.citi.com/ Logo
Citi
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Previous experience in a related role
  • Sound understanding in model audit, validation, or model risk management within financial services
  • Understanding of financial services regulations and how they intersect with AI/GenAI e.g. conduct risk, operational resilience, data protection, algorithmic trading, AML/KYC, consumer protection
  • Related certifications such as Certified Information Systems (CISA), Certified Internal Auditor (CIA), Certified in Risk and Information Systems (CRISC) or similar. AI-related certifications are a plus
  • Demonstrated successful experience in business, functional and people management
  • Proven ability to execute concurrently on a portfolio of high quality deliverables according to strict timetables
  • Demonstrated ability to implement continuous improvement and innovation in audit tools and techniques
  • Consistently demonstrates clear and concise written and verbal communication
  • Demonstrated ability to remain unbiased in a diverse working environment
  • Effective negotiation skills
Job Responsibility
Job Responsibility
  • Deliver audit reports, Internal Audit and Regulatory issue validation and business monitoring and governance committee reports relating to AI model development, validation and deployment
  • Act as a trusted subject matter experts on AI Model risks and controls across the IA team
  • Oversight of portfolios within the AI Non-model Objects team including stakeholder engagement, assessment of key emerging and inherent risks, etc
  • Participate in business initiatives and pro-actively advise and assist the business on change initiatives
  • Implement integrated auditing concepts and technology, and follow trends in the Audit field and adapt them for the Audit function
  • Identify solutions for a variety of complex and unique control issues, utilizing complex judgement and sophisticated analytical thought
  • Analyse report findings, and recommend interventions where needed, proposing creative and pragmatic solutions to risk and control issues
  • Partner with Directors and Managing Directors to develop approaches for addressing broader corporate emerging issues
  • Appropriately assess risk when business decisions are made, demonstrating particular consideration for the firm's reputation and safeguarding Citigroup, its clients and assets, by driving compliance with applicable laws, rules and regulations, adhering to Policy, applying sound ethical judgment regarding personal behavior, conduct and business practices, and escalating, managing and reporting control issues with transparency, as well as effectively supervise the activity of others and create accountability with those who fail to maintain these standards
What we offer
What we offer
  • Generous holiday allowance starting at 27 days plus bank holidays
  • increasing with tenure
  • A discretional annual performance related bonus
  • Private medical insurance packages to suit your personal circumstances
  • Employee Assistance Program
  • Pension Plan
  • Paid Parental Leave
  • Exclusive discounts for employees, family, and friends
  • Access to an array of learning and development resources
Read More
Arrow Right

Director of Commercial Analytics

Amgen is seeking a Director of Commercial Analytics to lead a high-impact analyt...
Location
Location
India , Hyderabad
Salary
Salary:
Not provided
amgen.com Logo
Amgen
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Doctorate degree / Master’s degree with 18+yrs of Industrial experience
  • 4 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources
Job Responsibility
Job Responsibility
  • Define and drive the Commercial Analytics strategy for India as a global hub with clear operating principles, methodologies, and delivery standards
  • Serve as a strategic thought partner to Commercial and CD&A leadership, shaping how performance is defined and measured
  • Design, harmonize, and govern enterprise KPIs with clear definitions and consistent methodologies across portfolio
  • Own the intake and prioritization model for commercial analytics work originating in India - aligning resources against enterprise priorities and managing trade-offs with US and global partners
  • Establish frameworks that guide how teams translate business needs into analytical approaches, ensuring clarity of decision context and expected outcomes
  • Lead commercial performance analytics to proactively identify opportunities, risks, and business drivers - informing portfolio decisions and commercial investment choices
  • Integrate insights across forecasting, market research, access, and decision science to deliver unified, cross-functional recommendations
  • Communicate insights with clarity and influence, using strong commercial judgment and structured storytelling
  • Drive automation, productization, and workflow reusability to reduce manual effort and accelerate decision cycles
  • Set the direction for AI-enabled insight generation - enabling automated commentary, predictive signals, and scalable analytics capabilities across markets
What we offer
What we offer
  • Reasonable accommodation for individuals with disabilities to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment
Read More
Arrow Right

Director, Product Quality Leader

This individual will serve as a technical quality expert for one or more product...
Location
Location
United States
Salary
Salary:
164000.00 - 225500.00 USD / Year
biomarin.com Logo
BioMarin Pharmaceutical
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • BA/BS in life sciences or related field required
  • Advanced degree desirable
  • 12+ years of experience with Biotechnology, Pharmaceutical, Medical Device or other, highly regulated, industry
  • Preferred experience in biologics product development and licensure or technical support
  • Experience in both clinical and commercial phases of product lifecycle is highly desirable
  • Experience supporting combination products across clinical and commercial stages, including device quality considerations, is a plus
  • Excellent interpersonal and communications skills
  • Demonstrated strong leadership capability
  • Experience with influencing diverse stakeholders and driving accountability and decision-making in a highly matrixed, cross-functional environment
  • Highly capable of building strong, effective working teams
Job Responsibility
Job Responsibility
  • Serve as a technical quality expert for one or more products during clinical development through post-commercialization
  • Make technical quality-related decisions
  • Serve as the single point of contact on the CMC team for all quality functions, risks and issues
  • Provide efficient and effective quality leadership of CMC-related strategic activities
  • Drive associated quality decisions
  • Participate fully in CMC team meetings and other relevant technical forums
  • Partner with CMC Team and the Quality organization to identify, develop and prioritize long-term product strategies/initiatives
  • Accountable for creation of the product-specific Quality strategy
  • Lead the cross-functional Quality Partner Team (QPT) supporting Quality-related CMC deliverables
  • Own and manage the product quality risk register
What we offer
What we offer
  • Discretionary annual bonus
  • Discretionary stock-based long-term incentives
  • Paid time off
  • Company-sponsored medical, dental, vision, and life insurance plans
  • Fulltime
Read More
Arrow Right
New

Director Network Spares Sourcing & Supply

Microsoft’s Cloud business continues to scale at an unprecedented pace, and the ...
Location
Location
United States , Redmond
Salary
Salary:
139900.00 - 274800.00 USD / Year
https://www.microsoft.com/ Logo
Microsoft Corporation
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Master's degree in Business, Supply Chain Management, Engineering, Materials Science, or related field AND 6+ years experience in procurement, supply chain, sourcing, engineering, operations, or relevant sales-related roles OR Bachelor's degree in Business, Supply Chain Management, Engineering, Materials Science, or related field AND 8+ years experience in procurement, supply chain, sourcing, engineering, operations, or relevant sales-related roles OR equivalent experience
  • Ability to meet Microsoft, customer and/or government security screening requirements are required for this role
  • These requirements include, but are not limited to, the following specialized security screenings: Microsoft Cloud Background Check: This position will be required to pass the Microsoft Cloud background check upon hire/transfer and every two years thereafter
  • 3+ years of people management experience
  • 10+ years of experience in spares supply chain, network/optics operations, or manufacturing, ideally within high tech environments
  • Proven success delivering medium-to-large scale programs in mission-critical industries, particularly Networking and Optics
  • Experience optimizing supplier performance and leading global capability improvements
  • Strong analytical and problem-solving skills with the ability to drive insights and collaboration across global teams
  • Deep knowledge of forward/reverse logistics, contract manufacturing, repair/refurbishment operations, and supply chain systems (ERP, CRM)
  • Strong understanding of product lifecycle management, including BOM maintenance and ECO processes
Job Responsibility
Job Responsibility
  • Develop and own Microsoft’s global Network Spares strategy to enable data center reliability and long term scalability
  • Guide executive decision making on portfolio priorities, investment tradeoffs, and risk mitigation across NW sparing
  • Benchmark industry practices and introduce outside innovation to enhance Microsoft’s Cloud Supply Chain
  • Lead end to end sourcing and supply operations for Networking spares, ensuring system, tool, and process readiness across near, mid, and long term horizons
  • Drive the rhythm of business including governance, KPI management, program tracking, and cross functional alignment
  • Oversee the accuracy of product lifecycle foundations including install base, BOMs, FRUs, and ECO management
  • Optimize global logistics footprint and supply chain flows to reduce cycle time, cost, and operational risk
  • Build and manage strategic supplier relationships to ensure strong RMA performance, depot inventory health, and operational compliance
  • Lead escalation management for RMA delays, establishing clear processes and engagement protocols across teams
  • Collaborate with internal and external partners to drive improvements in repair/refurbishment operations and contractual performance
  • Fulltime
Read More
Arrow Right

Director of Product Management

Silvus is seeking a Director of Product Management who will report to the Vice P...
Location
Location
United States , Los Angeles
Salary
Salary:
200000.00 - 240000.00 USD / Year
silvustechnologies.com Logo
Silvus Technologies (International)
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Bachelor’s degree in Engineering, Computer Science, or related field
  • Minimum 10 years of Product Management experience, including at least 3–5 years in a director or senior leadership role
  • Proven success building or scaling a Product Management organization in a complex technology company (hardware + software + systems)
  • Strong technical background and ability to engage deeply with engineering teams
  • Demonstrated strength in market analysis, business case development, and data-driven prioritization
  • Security Clearance: Active U.S. Government SECRET clearance or the ability to obtain one within 12 months of hire
  • Must be a U.S. Citizen due to clients under U.S. government contracts
  • All employment is contingent upon the successful clearance of a background check
Job Responsibility
Job Responsibility
  • Build the Product Management Organization
  • Be the founding leader of this team, initially focusing on strategic oversight and hands-on product ownership before scaling a dedicated team
  • Design, build, and lead a high-performing Product Management team
  • Define and institutionalize Silvus’ Product Management frameworks: roadmap planning, requirements management, portfolio governance, and lifecycle ownership
  • Champion the Product Management mindset across the company
  • Serve as the connective tissue between the Engineering, Marketing, Sales, and Operations teams to align decisions with business strategy and customer needs
  • Market & Portfolio Strategy
  • Develop a clear market-driven product strategy that identifies where Silvus should play, win, and invest
  • Lead portfolio prioritization based on market potential, ROI, and strategic value
  • Direct customer and OEM partner interaction as an ongoing activity
  • Fulltime
Read More
Arrow Right

Director of Product Management

Silvus is seeking a Director of Product Management who will report to the Vice P...
Location
Location
United States , Irvine; West Los Angeles
Salary
Salary:
200000.00 - 240000.00 USD / Year
silvustechnologies.com Logo
Silvus Technologies (International)
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Bachelor’s degree in Engineering, Computer Science, or related field
  • Minimum 10 years of Product Management experience, including at least 3–5 years in a director or senior leadership role
  • Proven success building or scaling a Product Management organization in a complex technology company (hardware + software + systems)
  • Strong technical background and ability to engage deeply with engineering teams
  • Demonstrated strength in market analysis, business case development, and data-driven prioritization
  • Security Clearance: Active U.S. Government SECRET clearance or the ability to obtain one within 12 months of hire
  • Must be a U.S. Citizen due to clients under U.S. government contracts
  • All employment is contingent upon the successful clearance of a background check
Job Responsibility
Job Responsibility
  • Build the Product Management Organization
  • Be the founding leader of this team, initially focusing on strategic oversight and hands-on product ownership before scaling a dedicated team
  • Design, build, and lead a high-performing Product Management team — including recruiting, mentorship, and professional development
  • Define and institutionalize Silvus’ Product Management frameworks: roadmap planning, requirements management, portfolio governance, and lifecycle ownership
  • Champion the Product Management mindset across the company — helping teams think in terms of markets, customers, value, and lifecycle impact
  • Serve as the connective tissue between the Engineering, Marketing, Sales, and Operations teams to align decisions with business strategy and customer needs
  • Market & Portfolio Strategy
  • Develop a clear market-driven product strategy that identifies where Silvus should play, win, and invest
  • Lead portfolio prioritization based on market potential, ROI, and strategic value
  • Direct customer and OEM partner interaction as an ongoing activity
  • Fulltime
Read More
Arrow Right
Jobs by Category
Art and Entertainment Jobs Banking Jobs Call Center Jobs Construction Jobs Consulting Jobs Customer Service Jobs Education Jobs Energy Jobs Finance Jobs Gastronomy Jobs Health and Beauty Jobs Hospitality and Tourism Jobs Human Resources Jobs Insurance Jobs IT - Administration Jobs IT - Software Development Jobs Legal Jobs Logistics Jobs Manufacturing Jobs Marketing, Digital Marketing, SEO, SEM Jobs Media Jobs Nursing Jobs Office Administration Jobs Pharmacy Jobs Physical Work Jobs Public Relations Jobs Public Sector Jobs Purchasing Jobs Quality Control Jobs Real Estate Jobs Research and Development Jobs Sales Jobs
Job Positions Jobs by Country
United States Jobs United Kingdom Jobs India Jobs Canada Jobs Australia Jobs Germany Jobs Ireland Jobs Poland Jobs
Company
Blog About Us Contact
Follow Us
Facebook
X (Twitter)
LinkedIn
Instagram
CrawlJobs Group
ITFlashcards AllDevBlogs
© 2026 CrawlJobs Ltd. All Rights Reserved
Terms & Conditions Privacy Policy