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Director, Operations and R&D Finance

United States, Pleasanton Employment contract 241400.00 - 326600.00 USD / Year · Job Posted April 24, 2026
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Job Description

At 10x Genomics, we are building the tools and services to master biology and advance human health. To fuel this mission, we need world-class financial leadership. We are looking for a leader who can be the primary business partner and financial architect for our global Operations and R&D organizations. You will drive the financial strategy across the entire product lifecycle: allocation of investment for new products and services, guiding our sourcing and manufacturing scale-up, and continuously improving COGS for on-market products. This includes managing $450M+ of annual spend spanning COGS, R&D, and capital expenditures. We expect you to be deeply immersed in the business; you will spend time on the manufacturing floor and in the labs with business partners, understanding the physical reality of our products to ensure every dollar spent drives both breakthrough innovation and sustaining cash flows.

Job Responsibility

  • Serve as the primary financial partner to the President & Chief Scientific Officer, Chief Technology Officer, and Chief of Global Operations
  • Own the end-to-end standard costing process and drive margin expansion through rigorous COGS and yield optimization across NPIs and on-market products
  • Bridge GAAP reporting (inventory reserves, warranty, absorption, etc) with plain-English insights and actionable analytics
  • Lead production planning, capex forecasting, and global supply chain partnerships
  • Develop and improve core operational analytics to guide rapid, data-driven decisions
  • Support pipeline investment decisions and Long-Range Planning (LRP) with robust financial frameworks
  • Evaluate platform-level ROI, capital allocation, and facilitate financial trade-off decisions from early-stage investment to commercial scale
  • Build and develop a world-class FP&A team
  • elevate the function by recruiting top analytical talent
  • Design and implement lean workflows and automated systems across the company to ensure the organization can support rapid growth without linear headcount expansion

Requirements

  • 12+ years of progressive finance experience, with at least 5 years in a senior leadership role
  • Deep cost accounting expertise in a manufacturing environment producing physical products
  • Experience managing $300M+ budgets spanning COGS, R&D, inventory, and capital expenditures across global sites
  • Strong command of US GAAP as it applies to manufacturing: standard costing, absorption, revenue recognition (ASC 606), inventory reserves, and warranty accounting
  • Proven team builder who has hired, developed, and retained high-caliber analytical talent
  • First-principles thinker who questions assumptions rather than defaulting to industry convention
  • Exceptional communicator who can make complex financial and cost accounting concepts intuitive for non-financial audiences
  • Promote transparency and visibility: ensure data, goals, and rationale are clear and accessible to build trust and accountability across all functions
  • Expert-level financial modeling skills, including complex scenario and sensitivity analysis, and proficiency in building scalable models in Excel
  • Bachelor's degree in Finance, Accounting, Economics, or a quantitative field

Nice to have

  • MBA or graduate degree in a quantitative discipline
  • Background or genuine interest in life sciences
  • Experience with ERP systems (Oracle preferred) and fluency in how financial systems connect to manufacturing execution systems
  • Data analytics skills and experience (Tableau, Power Pivot, Power Query, SQL, R, Python, etc.)

What we offer

  • Equity grants
  • Comprehensive health and retirement benefit programs
  • Annual bonus program or sales incentive program
  • Generous time off
  • Family friendly policies like parental leave
  • Competitive and comprehensive health benefits package
  • Competitive easy-to-use benefits that promote wellbeing

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