Director, Oncology Clinical Biomarkers Job at GSK (Collegeville)

Physician Director Oncology Data Science - Translational Science

Are you looking for an opportunity to lead a Translational Data Science team wit...

Location

United States , Collegeville, Pennsylvania

Salary:

Not provided

GSK

Expiration Date

Until further notice

Requirements

medical degree
Completion of a clinical residency program leading to board qualification or certification in internal medicine, pathology, pediatrics is required
10 years plus academic or industry experience in Computational Biology, Bioinformatics, or Translational/Clinical AI with focus on Oncology
5 years of leadership or matrix leadership experience in Computational Biology, Applied AI/ML, Cancer Biology or a related field

Job Responsibility

Lead and build a growing team of Translational Data Scientists to support and innovate the Oncology portfolio pipeline
Leverage your clinical training and experience to translate complex computational and molecular insights into clinically meaningful hypotheses, study designs, and biomarker strategies that directly inform patient care and oncology clinical development
Contribute scientific expertise and design to multiple drug discovery or development efforts across oncology
Act as a competent and recognized expert in developing and critiquing the scientific validity of research/development initiatives to drive the development and delivery of long-term scientific strategy in Oncology Genomics
Individually contribute with analyses and integration of complex cancer datasets. This includes analysis of histopathology imaging data, gene & protein expression (bulk + single cell + spatial), somatic mutations, copy number alterations, and structural variants
Apply statistical methods and AI/machine learning algorithms to identify patterns in data, predict drug response, and discover potential biomarkers. Critically evaluate results. Conduct survival analysis to assess the impact of various factors on patient outcomes
Lead the development and use of bioinformatics pipelines
Serve as a recognized leader in driving technological foresight within specific scientific function or directing content of programs
Lead and influence the outcome of multidisciplinary meetings including partners in therapeutic research units, translational and clinical development teams.
Communicate complex scientific findings clearly to both technical and non-technical audiences.

What we offer

Competitive base salary
Annual bonus based on company performance
Flexible working options available for most roles
Learning and career development
Access to healthcare & wellbeing programmes
Employee recognition programmes

Fulltime

New

Executive Director, Research Oncology

Let’s do this. Let’s change the world. In this vital role as the Executive Direc...

Location

United States , South San Francisco

Salary:

257890.00 - 348910.00 USD / Year

Amgen

Expiration Date

Until further notice

Requirements

Doctorate degree & 6 years of oncology research experience OR Master’s degree & 10 years of oncology research experience OR Bachelor’s degree & 12 years of oncology research experience AND 6 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources

Job Responsibility

Drive research strategy and execution for a differentiated oncology portfolio. This effort will initially focus on ADCs and is expected to expand into other modalities
Lead and develop high-performing teams of project leaders and scientists, fostering a culture of innovation, accountability, and growth
Advance preclinical programs and partner cross-functionally with clinical development and biomarker teams to translate insights into next-generation therapies
Leverage data and technology to accelerate discovery and decision-making
Shape external collaborations, including academic partnerships and business development opportunities

What we offer

Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans and bi-annual company-wide shutdowns
Flexible work models where possible

Fulltime

Director, Diagnostics

This Diagnostic Lead role will implement Dx development GSK Development wide enc...

Location

United States; United Kingdom , Collegeville; Stevenage; Waltham; Upper Providence

Salary:

189750.00 - 316250.00 USD / Year

GSK

Expiration Date

Until further notice

Requirements

Ph.D. in Biological Sciences and 5 years of pharmaceutical and/or diagnostic industry experience or B.S or M.S. with 7 years of pharmaceutical and diagnostic industry experience
Experience in drug / diagnostic development especially late stage development, regulatory approval and life cycle management (eg follow on Dx)
Experience with technical platforms that include IHC, immunoassay, PCR, NGS and novel assay technologies (digital pathology, liquid biopsy, multiplex technologies)
Experience in IVD development including design history file evaluation, risk assessments and all related analytical and clinical validation requirements
Experience performing due diligence and audit of Dx developers
Experience with GCP/GCLP, CLIA, CAP, ISO15189 laboratory requirements
Experience with QSR regulations, GMP manufacturing, ISO13485, and FDA and EU medical device regulations
Experience with clinical trial design and execution (efficacy endpoints, biomarker testing), sample operations, data management and human biological specimen management)
Experience with MS Office products (Word, Excel, PowerPoint, SharePoint, Project) and remote meeting tools such as MS Teams

Job Responsibility

Manage the team of associate directors, diagnostics. Team manager to deliver on the vision of equipping GSK to be a leader in oncology through Dx development driving the portfolio value
Monitor and report projects progress, outcomes, KPIs eg delivery of Target Diagnostic Profile
Remove barriers to Dx strategy development and implementation, collaborating cross functionally with clinical operations, external engagement, procurement, etc…
Exhibits timely management and delivery of projects/work streams within agreed budget
Must be able to manage multiple projects and work streams across TAs and R&D, including assessment of workload and resourcing requirements to deliver the team’s objectives
Clearly and concisely report project progress and outcomes, coordinating with project management, finance and business operations
Ensure learnings and best practices are shared and adopted for effective delivery
Participate in the evaluation of advanced technologies for IVD and clinical biomarker development
Keep a pulse on team execution and cross-functional ways of working with clinical, regulatory, operations, policy, BD and business unit colleagues and key leadership within project teams
Provides frequent project status updates / reports related to Dx deliverables

What we offer

Annual bonus
Eligibility to participate in our share based long term incentive program
Health care and other insurance benefits (for employee and family)
Retirement benefits
Paid holidays
Vacation
Paid caregiver/parental and medical leave

Fulltime

New

Director, Oncology Research

Let’s do this. Let’s change the world. Amgen is a leader in the discovery and de...

Location

United States , South San Francisco

Salary:

215300.75 - 291289.25 USD / Year

Amgen

Expiration Date

Until further notice

Requirements

Doctorate degree in Cancer Biology, Cell Biology, Genetics, or related field and 5 years of directly related experience
OR Master's degree in Cancer Biology, Cell Biology, Genetics, or related field and 8 years of directly related experience
OR Bachelor's degree in Cancer Biology, Cell Biology, Genetics, or related field and 10 years of directly related experience

Job Responsibility

Lead preclinical research for T-cell engager clinical programs and external collaborations, focused on lung and neuroendocrine cancer
Build and lead a portfolio of innovative research programs focused on bispecific antibodies
Mentor a team of project leaders and lab-based scientists to discover new biology, deliver robust datasets and make critical decisions for therapeutic programs and technology platforms
Contribute to the identification and evaluation of external research opportunities, including business development partnerships and academic collaborations
Partner effectively with peers across research and development to advance new science and integrate technology with tumor cell biology, including application of AI/ML approaches to target evaluation and biomarker discovery

What we offer

Comprehensive employee benefits package including Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
Discretionary annual bonus program or sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible

Fulltime

Associate Director Medical Writer

The Associate Director Medical Writer is an individual expert who can manage and...

Location

Canada , Mississauga

Salary:

Not provided

GSK

Expiration Date

Until further notice

Requirements

PhD or relevant working experience within the life sciences space
Proven track record in writing clinical/regulatory documents including, but not limited to: protocols, clinical study reports, NDA/MAA CTD submission documents, investigator brochures, briefing documents, and responses to regulatory authority questions
Work in a matrix team to ensure delivery of high quality, fit-for-purpose clinical documents that accurately reflect associated data, and are in line with GSK standards and global, regional and/or local regulatory requirements
Experienced as a significant contributor in planning and production of clinical dossier documents for regulatory submissions worldwide
Demonstrated effectiveness in management of projects of increasing scope and complexity
Understanding of the interdependencies of various contributing functions (e.g., clinical pharmacology, biomarkers, health outcome)
Ability to quickly assess complex situations, apply scientific, operational, and submission development knowledge and implement effective plans for solutions
High-level computer skills and general computer literacy
Demonstrated knowledge of scientific methodology and statistical principles in the design, conduct and description of clinical research
Ability to interpret clinical data, assess trends and patterns in text and statistical data, and effectively organize content and messages in clinical reports and summary documents

Job Responsibility

Contribute to the planning, authoring, review, and approval of clinical/regulatory documents for medical writing project to achieve a successful outcome within the required timelines
Possess highly effective communication skills and is capable of presenting ideas and data clearly to a group, including key stakeholders at a senior level
Provide major input to submission teams in development of submission plans, timelines, document content and dependencies
Advises on or recommends methods for achieving accelerated timelines, including review tools and automation
Actively contribute to development of training materials for clinical document preparation
provides mentoring and/or training on clinical documentation and submission planning to individuals or teams
Champion change and contributes to departmental or cross-functional process improvement initiatives and develops/revises standards for GSK submission documents
Effectively contribute to process improvement activities

What we offer

Competitive base salary
Annual bonus based on company performance
Flexible working options available for most roles
Learning and career development
Access to healthcare & wellbeing programmes
Employee recognition programmes

Fulltime

New

Obstetrics/Gynecology Physician

Locum Obstetrics/Gynecology Physician Job in Christiansburg, VA. Aya Locums has ...

Location

United States , Christiansburg

Salary:

Not provided

Aya Locums

Expiration Date

Until further notice

Requirements

Doctor of Medicine (MD) degree or Doctor of Osteopathic Medicine (DO) degree from an accredited medical school
Residency training program in obstetrics and gynecology accredited by the Accreditation Council for Graduate Medical Education (ACGME) or the American Osteopathic Association (AOA)
Board certification in obstetrics and gynecology by the American Board of Obstetrics and Gynecology (ABOG) or the AOA
Active and unrestricted medical license in Virginia
At least one year of experience providing obstetric and gynecological care in a clinical or hospital setting

Job Responsibility

Provide comprehensive healthcare for women across all stages of life
Conduct gynecological exams, ultrasounds and other diagnostic procedures
Perform surgical procedures, such as hysterectomies, cesarean sections and minimally invasive surgeries
Diagnose and treat a wide range of women's health conditions
Provide counseling on reproductive health, contraception and family planning
Collaborate with other healthcare professionals, such as pediatricians and neonatologists, for optimal patient care
Maintain accurate and complete medical records for all patients
Stay current on the latest advancements in obstetrics and gynecology through continuing education

What we offer

Access to top hospitals and healthcare systems in diverse care settings
Highly competitive, transparent locum tenens pay
Dedicated application and assignment support
In-house credentialing and licensing teams
Travel and lodging coverage
Easy timekeeping and streamlined management of documents
Malpractice coverage and risk management support
Reimbursements (where required by applicable law)

Fulltime

New

Ai Developer

Wissen Technology is hiring for AI Developer. At Wissen Technology, we deliver n...

Location

India , Mumbai

Salary:

Not provided

Wissen

Expiration Date

Until further notice

Requirements

4–10 years of experience in AI/ML development or software engineering
Strong proficiency in Python for AI/ML development
Hands-on experience with LLMs and GenAI frameworks
Expertise in building RAG pipelines, embeddings, and vector search systems
Experience with LangChain, LlamaIndex, LangGraph, or similar orchestration frameworks
Knowledge of AI agents and workflow automation architectures
Experience integrating AI into APIs and microservices-based systems
Familiarity with cloud platforms (AWS, Azure, GCP)
Strong understanding of AI evaluation methods, model optimization, and guardrails
Solid problem-solving, analytical thinking, and communication skills

Job Responsibility

Build and deploy GenAI applications using LLMs such as GPT, Gemini, Llama, Mistral, Claude, etc.
Design and implement RAG pipelines using vector databases and embedding
Develop AI agents and workflow orchestration using LangChain, LangGraph, CrewAI, AutoGen, or similar frameworks
Fine-tune, evaluate, and optimize LLM models for production use cases
Integrate AI services into scalable backend systems and APIs
Work with structured/unstructured datasets for NLP and AI workflows
Deploy AI solutions on cloud platforms such as Azure, AWS, or GCP
Build observability, monitoring, guardrails, and evaluation frameworks for GenAI systems
Collaborate with product, engineering, and business teams to deliver AI-driven solutions
Mentor junior engineers and contribute to AI architecture decisions (for senior roles)

Fulltime

New

Car Delivery Driver

As a Car Delivery Driver, you’ll be the face of Domino’s in your local community...

Location

United Kingdom , Alloa

Salary:

10.85 - 12.71 GBP / Hour

360 Resourcing Solutions

Expiration Date

Until further notice

Requirements

Full, valid UK or International driving licence
Own a reliable, roadworthy car with valid MOT, tax, and insurance
Smartphone for delivery app use
Good knowledge of the local area
Friendly, reliable, and able to work independently
Able to work flexible hours, including evenings and weekends

Job Responsibility

Deliver pizzas and menu items to customers promptly and safely
Provide excellent customer service at every doorstep
Operate your vehicle in accordance with road safety regulations
Use the Domino’s Delivery App on your smartphone to manage orders
Support the in-store team during quieter delivery periods (e.g. cleaning, restocking, folding boxes)
Represent Domino’s positively in the community

What we offer

Competitive hourly pay + per-delivery payment + tips
28 days paid holiday per year (includes BH, pro rata for part time)
Flexible working hours to suit your lifestyle
Staff discount on our delicious food
Occasional Business Use insurance provided whilst out driving
Staff meals (conditions apply)
Company pension scheme (where eligible)
Family Leave policies in place
Paid training and clear career progression pathway with linked pay increases
Supportive, inclusive, and fun team environment

Select Country

Director, Oncology Clinical Biomarkers

GSK

Location:
United States; United Kingdom , Collegeville ▼
London
Stevenage
Waltham

Category:
Research and Development

Contract Type:
Employment contract

Salary:

Job Description:

Job Responsibility:

Requirements:

Nice to have:

Additional Information:

Job Posted:
May 10, 2026

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