Director, Oncology Clinical Biomarkers Job at GSK (Collegeville)

Director, Oncology Research

Let’s do this. Let’s change the world. Amgen is a leader in the discovery and de...

Location

United States , South San Francisco

Salary:

215300.75 - 291289.25 USD / Year

Amgen

Expiration Date

Until further notice

Requirements

Doctorate degree in Cancer Biology, Cell Biology, Genetics, or related field and 5 years of directly related experience
OR Master's degree in Cancer Biology, Cell Biology, Genetics, or related field and 8 years of directly related experience
OR Bachelor's degree in Cancer Biology, Cell Biology, Genetics, or related field and 10 years of directly related experience

Job Responsibility

Lead preclinical research for T-cell engager clinical programs and external collaborations, focused on lung and neuroendocrine cancer
Build and lead a portfolio of innovative research programs focused on bispecific antibodies
Mentor a team of project leaders and lab-based scientists to discover new biology, deliver robust datasets and make critical decisions for therapeutic programs and technology platforms
Contribute to the identification and evaluation of external research opportunities, including business development partnerships and academic collaborations
Partner effectively with peers across research and development to advance new science and integrate technology with tumor cell biology, including application of AI/ML approaches to target evaluation and biomarker discovery

What we offer

Comprehensive employee benefits package including Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
Discretionary annual bonus program or sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible

Fulltime

Physician Director Oncology Data Science - Translational Science

Are you looking for an opportunity to lead a Translational Data Science team wit...

Location

United States , Collegeville, Pennsylvania

Salary:

Not provided

GSK

Expiration Date

Until further notice

Requirements

medical degree
Completion of a clinical residency program leading to board qualification or certification in internal medicine, pathology, pediatrics is required
10 years plus academic or industry experience in Computational Biology, Bioinformatics, or Translational/Clinical AI with focus on Oncology
5 years of leadership or matrix leadership experience in Computational Biology, Applied AI/ML, Cancer Biology or a related field

Job Responsibility

Lead and build a growing team of Translational Data Scientists to support and innovate the Oncology portfolio pipeline
Leverage your clinical training and experience to translate complex computational and molecular insights into clinically meaningful hypotheses, study designs, and biomarker strategies that directly inform patient care and oncology clinical development
Contribute scientific expertise and design to multiple drug discovery or development efforts across oncology
Act as a competent and recognized expert in developing and critiquing the scientific validity of research/development initiatives to drive the development and delivery of long-term scientific strategy in Oncology Genomics
Individually contribute with analyses and integration of complex cancer datasets. This includes analysis of histopathology imaging data, gene & protein expression (bulk + single cell + spatial), somatic mutations, copy number alterations, and structural variants
Apply statistical methods and AI/machine learning algorithms to identify patterns in data, predict drug response, and discover potential biomarkers. Critically evaluate results. Conduct survival analysis to assess the impact of various factors on patient outcomes
Lead the development and use of bioinformatics pipelines
Serve as a recognized leader in driving technological foresight within specific scientific function or directing content of programs
Lead and influence the outcome of multidisciplinary meetings including partners in therapeutic research units, translational and clinical development teams.
Communicate complex scientific findings clearly to both technical and non-technical audiences.

What we offer

Competitive base salary
Annual bonus based on company performance
Flexible working options available for most roles
Learning and career development
Access to healthcare & wellbeing programmes
Employee recognition programmes

Fulltime

Executive Director, Research Oncology

Let’s do this. Let’s change the world. In this vital role as the Executive Direc...

Location

United States , South San Francisco

Salary:

257890.00 - 348910.00 USD / Year

Amgen

Expiration Date

Until further notice

Requirements

Doctorate degree & 6 years of oncology research experience OR Master’s degree & 10 years of oncology research experience OR Bachelor’s degree & 12 years of oncology research experience AND 6 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources

Job Responsibility

Drive research strategy and execution for a differentiated oncology portfolio. This effort will initially focus on ADCs and is expected to expand into other modalities
Lead and develop high-performing teams of project leaders and scientists, fostering a culture of innovation, accountability, and growth
Advance preclinical programs and partner cross-functionally with clinical development and biomarker teams to translate insights into next-generation therapies
Leverage data and technology to accelerate discovery and decision-making
Shape external collaborations, including academic partnerships and business development opportunities

What we offer

Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans and bi-annual company-wide shutdowns
Flexible work models where possible

Fulltime

Associate Director Medical Writer

The Associate Director Medical Writer is an individual expert who can manage and...

Location

Canada , Mississauga

Salary:

Not provided

GSK

Expiration Date

Until further notice

Requirements

PhD or relevant working experience within the life sciences space
Proven track record in writing clinical/regulatory documents including, but not limited to: protocols, clinical study reports, NDA/MAA CTD submission documents, investigator brochures, briefing documents, and responses to regulatory authority questions
Work in a matrix team to ensure delivery of high quality, fit-for-purpose clinical documents that accurately reflect associated data, and are in line with GSK standards and global, regional and/or local regulatory requirements
Experienced as a significant contributor in planning and production of clinical dossier documents for regulatory submissions worldwide
Demonstrated effectiveness in management of projects of increasing scope and complexity
Understanding of the interdependencies of various contributing functions (e.g., clinical pharmacology, biomarkers, health outcome)
Ability to quickly assess complex situations, apply scientific, operational, and submission development knowledge and implement effective plans for solutions
High-level computer skills and general computer literacy
Demonstrated knowledge of scientific methodology and statistical principles in the design, conduct and description of clinical research
Ability to interpret clinical data, assess trends and patterns in text and statistical data, and effectively organize content and messages in clinical reports and summary documents

Job Responsibility

Contribute to the planning, authoring, review, and approval of clinical/regulatory documents for medical writing project to achieve a successful outcome within the required timelines
Possess highly effective communication skills and is capable of presenting ideas and data clearly to a group, including key stakeholders at a senior level
Provide major input to submission teams in development of submission plans, timelines, document content and dependencies
Advises on or recommends methods for achieving accelerated timelines, including review tools and automation
Actively contribute to development of training materials for clinical document preparation
provides mentoring and/or training on clinical documentation and submission planning to individuals or teams
Champion change and contributes to departmental or cross-functional process improvement initiatives and develops/revises standards for GSK submission documents
Effectively contribute to process improvement activities

What we offer

Competitive base salary
Annual bonus based on company performance
Flexible working options available for most roles
Learning and career development
Access to healthcare & wellbeing programmes
Employee recognition programmes

Fulltime

Director, Diagnostics

This Diagnostic Lead role will implement Dx development GSK Development wide enc...

Location

United States; United Kingdom , Collegeville; Stevenage; Waltham; Upper Providence

Salary:

189750.00 - 316250.00 USD / Year

GSK

Expiration Date

Until further notice

Requirements

Ph.D. in Biological Sciences and 5 years of pharmaceutical and/or diagnostic industry experience or B.S or M.S. with 7 years of pharmaceutical and diagnostic industry experience
Experience in drug / diagnostic development especially late stage development, regulatory approval and life cycle management (eg follow on Dx)
Experience with technical platforms that include IHC, immunoassay, PCR, NGS and novel assay technologies (digital pathology, liquid biopsy, multiplex technologies)
Experience in IVD development including design history file evaluation, risk assessments and all related analytical and clinical validation requirements
Experience performing due diligence and audit of Dx developers
Experience with GCP/GCLP, CLIA, CAP, ISO15189 laboratory requirements
Experience with QSR regulations, GMP manufacturing, ISO13485, and FDA and EU medical device regulations
Experience with clinical trial design and execution (efficacy endpoints, biomarker testing), sample operations, data management and human biological specimen management)
Experience with MS Office products (Word, Excel, PowerPoint, SharePoint, Project) and remote meeting tools such as MS Teams

Job Responsibility

Manage the team of associate directors, diagnostics. Team manager to deliver on the vision of equipping GSK to be a leader in oncology through Dx development driving the portfolio value
Monitor and report projects progress, outcomes, KPIs eg delivery of Target Diagnostic Profile
Remove barriers to Dx strategy development and implementation, collaborating cross functionally with clinical operations, external engagement, procurement, etc…
Exhibits timely management and delivery of projects/work streams within agreed budget
Must be able to manage multiple projects and work streams across TAs and R&D, including assessment of workload and resourcing requirements to deliver the team’s objectives
Clearly and concisely report project progress and outcomes, coordinating with project management, finance and business operations
Ensure learnings and best practices are shared and adopted for effective delivery
Participate in the evaluation of advanced technologies for IVD and clinical biomarker development
Keep a pulse on team execution and cross-functional ways of working with clinical, regulatory, operations, policy, BD and business unit colleagues and key leadership within project teams
Provides frequent project status updates / reports related to Dx deliverables

What we offer

Annual bonus
Eligibility to participate in our share based long term incentive program
Health care and other insurance benefits (for employee and family)
Retirement benefits
Paid holidays
Vacation
Paid caregiver/parental and medical leave

Fulltime

It Regulatory Compliance Engineer

We are looking for an IT Regulatory Compliance Engineer to support product compl...

Location

United States , San Antonio

Salary:

Not provided

Robert Half

Expiration Date

Until further notice

Requirements

Bachelor’s degree in Mechanical Engineering, Electrical Engineering, or a closely related technical discipline
At least 5 years of experience in regulatory compliance, product safety, quality, or a related engineering environment
Working knowledge of regulatory frameworks, internal controls, and industry standards relevant to product compliance and risk management
Experience conducting risk assessments, supporting regulatory audits, and managing documentation for certifications or approvals
Familiarity with engineering change processes, including review of design revisions, change orders, and controlled deviations
Strong analytical judgment, problem-solving ability, and report-writing skills in a regulated manufacturing setting
Proficiency with compliance management systems, documentation tools, and standards-based quality frameworks such as ISO environments
Effective communication and collaboration skills
Spanish language ability is a plus

Job Responsibility

Guide product compliance activities to confirm equipment aligns with applicable safety, emissions, immunity, and market-specific regulatory standards before release
Prepare and maintain technical documentation packages required for third-party approvals, certifications, and regulatory submissions
Manage ongoing certification status as product designs evolve, including updates tied to new features, displays, connectivity capabilities, or configuration changes
Oversee food safety and hygienic design compliance for applicable products by maintaining required records, supporting certifications, and addressing material and market-specific standards
Perform compliance and hazard assessments, recommend mitigation actions, and help implement controls that reduce regulatory and product-related risk
Coordinate testing schedules with external laboratories and regulatory agencies while communicating technical requirements to engineering and other internal teams
Partner with suppliers and manufacturing partners to verify supporting certification evidence and confirm materials, components, and processes meet required standards
Review engineering changes, deviations, and related documentation to ensure regulatory obligations are addressed in product updates and change control workflows
Support internal and external audits, respond to findings, monitor renewal timelines, and provide regulatory information to agencies and customers as needed
Contribute to compliance training, continuous improvement initiatives, and best-practice adoption that strengthen manufacturing quality and regulatory readiness

What we offer

Medical, vision, dental, and life and disability insurance
401(k) plan
Free online training

Fulltime

Director of Sales

The Community Sales Director (“CSD”) is responsible for achieving and exceeding ...

Location

United States , Tyler

Salary:

Not provided

Atria Senior Living

Expiration Date

Until further notice

Requirements

One (1) or more years of related sales experience
Must possess strong customer service skills, basic financial knowledge of revenue and profitability, strong computer and electronic file management skills and strong organizational skills
Must have the ability to maintain confidentiality
Must be organized, detail-oriented, and able to multi-task
As dictated by business needs, must be able to work flexible hours, including evenings, weekends, and holidays
Position requires driving responsibilities (may use Company provided vehicle and/or personal vehicle)
Must possess valid driver's license

Job Responsibility

Achieving and exceeding the community's monthly and quarterly revenue/sales targets
Developing the community's internal and external marketing
Building the community's strategic relationships with various referral sources to produce highly qualified inquiries
Promoting the leasing and marketing success of the community
Spending over 50% of time outside of the community generating inquires to meet and exceed monthly and quarterly revenue targets
Generating inquiries and move-ins from targeted referral sources by developing and maintaining relationships outside of the community
Collaborating with Executive Director to forecast move-ins accurately
Facilitating training and continuous in-servicing for all community staff that may field an inquiry call or conduct a walk-in or scheduled tour
Ensuring that responses to inquiries are handled properly, timely and with appropriate follow-up
Positioning ED or Resident Services Director as local experts on aging through facilitating introductions, joint sales calls, and strategic sales & marketing events

What we offer

Competitive Pay
Paid Holidays & PTO
Comprehensive Health Plans
Career Advancement Opportunities
Tuition Reimbursement
Employee Loyalty Rewards Program
Retirement Savings Plan with Employer Match
Rewards & Recognition
Health & Safety

Fulltime

Maintenance Technician

Location

Canada , Saint-Laurent

Salary:

Not provided

Atria Senior Living

Expiration Date

Until further notice

Requirements

High School Diploma or General Education Degree (GED)
Two (2) years of hands-on maintenance experience in areas such as plumbing, electrical, carpentry, HVAC, etc required
Ability to perform basic arithmetic skills, including measurement in order to do basic calculations, estimating, and determining averages
Demonstrated ability to use independent judgment and discretion to make decisions designed to achieve the Company's goals
Demonstrated experience in safe handling and use of tools normally used in construction, maintenance, and landscaping, including but not limited to circular saw, power drill, bench grinder, string trimmer, hedge trimmer, power floor cleaner, carpet cleaner, paint sprayer, ladders, pressure washers, etc.
Basic computer skills and ability to operate standard office equipment
Ability to transport up to 50 pounds variable distances and to access and work in confined spaces or heights in excess of 8-9 feet
Familiar with all types of surfaces and respective cleaners
Experience in carpet cleaning and upholstery cleaning
Understanding of Lock Out/Tag Out procedures

Job Responsibility

Participate in the preparation of ready-to-occupy apartments, which may include painting, carpet cleaning, general repairs and housekeeping
Manage all maintenance needs of the community to ensure the physical condition of the community meets or exceeds the Company's standards
Perform various preventative maintenance functions and complete all necessary data collection and submission
Manage all customer service requests using the Company work order system, including prioritization of requests
Complete daily community inspections including keeping grounds and common areas free of trash and debris
Perform various maintenance functions such as electrical installations, pool maintenance, carpentry/construction, furnace and air conditioner repairs, filter changing, coil cleaning, plumbing and appliance repairs, drywall and painting repairs, vinyl installation and repairs, minor roof repairs, etc.
Monitor the maintenance and upkeep of all mechanical equipment in the community, including but not limited to fire safety systems, water heaters, HVAC units, kitchen equipment, etc.
Partner with contractors/subcontractors as required to meet the needs of the community
Organize maintenance storage and mechanical rooms
Ensure proper use and care of all tools, equipment, and vehicles

What we offer

Competitive Pay
Paid Holidays & PTO
Comprehensive Health Plans (medical, vision, and dental coverage, company paid short term and long term disability, as well as other voluntary benefits such as critical illness coverage)
Career Advancement Opportunities
Tuition Reimbursement (up to $5,250 a year)
Employee Loyalty Rewards Program
Retirement Savings Plan with Employer Match (50% match)
Rewards & Recognition
Health & Safety

Fulltime

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Director, Oncology Clinical Biomarkers

Job Description

Job Responsibility

Requirements

Nice to have

What we offer

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