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Director of protein science

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Randstad

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Location:
China , Shanghai

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Contract Type:
Not provided

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Salary:

900000.00 - 1200000.00 CNY / Year

Job Description:

The client is an early-stage company backed by leading investors and experienced biotech executives.

Job Responsibility:

  • Lead the expression, purification, and characterization of antibody-based therapeutics (monospecifics, bispecifics, Fc fusions, and conjugates)
  • Drive innovation in biologics production — including heterodimerization control, conjugation (enzymatic, click, or linker-based), and modular payload formats (peptide, oligo, or protein)
  • Build and oversee robust workflows for high-throughput protein production, analytical and developability characterization, integrating automation and informatics where appropriate
  • Apply biophysical, biochemical, and structural analyses (e.g., HPLC, MS, BLI, DSC, DSF, ITC, SPR, ELISA, CE-SDS) to ensure optimal developability and stability of molecules
  • Partner with CMC, toxicology, and translational functions to progress molecules toward IND enabling studies
  • Establish and manage productive relationships with CROs and CDMOs for antibody discovery, characterization, and manufacturing
  • Identify and integrate emerging technologies (e.g., AI-driven design, machine learning-guided developability prediction, or microfluidics-based screening) to strengthen BraneX’s platform
  • Mentor and grow a high-performing Protein Sciences team while fostering scientific rigor, collaboration, and innovation
  • Ensure strong documentation and data integrity (ELN/SOP discipline) in support of IP, regulatory filings, and data room readiness

Requirements:

  • PhD in Biochemistry, Molecular Biology, Structural Biology, or related field
  • ≥10 years of postdoctoral experience, including ≥5 years in a biotech or pharma setting with demonstrated impact in biologics discovery or engineering
  • Deep expertise in antibody and bispecifics expression, purification, and characterization
  • proven track record of advancing biologics toward development candidates
  • Demonstrated experience with biophysical and biochemical methods supporting protein stability, binding, and developability
  • Experience balancing internal and outsourced workflows and managing cross-functional scientific projects
  • Strong leadership, communication, and mentoring skills, with the ability to inspire a multidisciplinary team in a fast-paced startup environment
  • Strong ELN/SOP discipline and data-driven mindset

Additional Information:

Job Posted:
March 26, 2026

Expiration:
June 03, 2026

Employment Type:
Fulltime
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