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Proclinical is seeking a Director, Process Innovation to lead discovery-stage process development and analytical innovation for an emerging lentiviral vector platform. This is a strategic leadership role focused on early-stage process design, platform building, and technical de-risking, rather than routine manufacturing or late-stage CMC. You will play a critical role in shaping how vectors are produced, characterized, and translated from bench to scalable bioreactor systems - creating the technical foundation that future CMC teams will build upon.
Job Responsibility:
Define and drive the vision for early process innovation in lentiviral vector production, operating at the interface of discovery science and enabling technologies
Design and optimize processes suitable for small-scale bioreactor manufacturing
Lead the development of fit-for-purpose analytical methods to assess vector quality, potency, and consistency at the discovery stage
Support the engineering of novel production cell lines to enable next-generation vector platforms
Collaborate closely with discovery scientists, CMC, QA, and external CDMOs to ensure alignment and future tech-transfer readiness
Provide expert technical judgment, critically evaluating experimental plans, data packages, and external deliverables
Build, mentor, and inspire a high-performing team that values innovation, rigor, and accountability
Requirements:
MSc or PhD in Virology, Biochemistry, Cell Biology, Molecular Biology, Biomedical Engineering, or a related discipline
Proven years of industry experience in bioprocess development and analytical sciences, ideally within viral vectors
Proven leadership in early-stage process development, preferably with lentiviral systems
Experience working with and overseeing CDMOs or external manufacturing partners
Solid understanding of regulatory expectations for gene or cell therapy CMC development
Strong communication skills, collaborative mindset, and a passion for advancing transformative medicines