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Director of Data Management & Biometrics

United Kingdom · Job Posted January 25, 2026
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Job Description

This is a senior leadership role, responsible for shaping and delivering the strategy for clinical data management, biostatistics, and biometrics functions across global clinical programmes. This role provides a rare opportunity to lead and scale a world-class data organisation that ensures rigorous, compliant and insightful delivery of clinical data to support regulatory submissions and scientific decision-making.

Job Responsibility

  • Lead and develop the Data Management & Biometrics function, including Clinical Data Management (CDM), Biostatistics, Statistical Programming, and medical coding standards
  • Own the design and delivery of data strategies that ensure high data quality, integrity and compliance throughout clinical development
  • Oversee development and implementation of data standards, CRF design, data flow plans, and database build/validation strategies
  • Partner with Clinical Operations, Safety, Regulatory, and IT to implement leading?edge technologies (e.g., EDC, eCOA, RTSM, CDISC standards)
  • Drive statistical analysis planning, statistical methods, and interpretation of complex clinical datasets
  • Ensure delivery of high-quality, timely outputs for interim looks, IDMC reporting, regulatory submissions, and final study reports
  • Represent Data Management & Biometrics in leadership forums, influencing cross-functional decision-making and resource prioritisation.

Requirements

  • Advanced degree in Statistics, Biostatistics, Computer Science, Life Sciences, or related discipline
  • MSc/PhD preferred
  • Significant leadership experience in clinical data management and biostatistics within a biopharmaceutical or CRO environment
  • Proven track record of building and managing high?performing biometrics teams through multiple phases of clinical development
  • Deep knowledge of CDISC standards (SDTM, ADaM), regulatory expectations, and EDC/CTMS environments
  • Demonstrated experience with advanced analytics, data standards, and clinical database design
  • Exceptional communicator with the ability to collaborate across functions, present to senior leadership, and engage external partners.

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