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Director, Data Engineering & Analytics

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Apogee Therapeutics

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Location:
United States

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Contract Type:
Not provided

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Salary:

220000.00 - 235000.00 USD / Year

Job Description:

We are seeking a Director, Data Engineering & Analytics to be a hands-on, individual contributor leading the design, implementation, and evolution of Apogee’s new enterprise Data Lakehouse and analytics ecosystem. This role will be the primary internal owner of our Data Lakehouse, delivered in partnership with a Systems Integrator, and will initially focus on Clinical Development and Clinical Operations use cases (e.g., study oversight, medical monitoring, operational performance). Over time, the platform will expand to support Technical Operations, Commercial, Medical Affairs, and Finance.

Job Responsibility:

  • Serve as the primary owner of Apogee’s Data Lakehouse architecture, roadmap, and implementation
  • Define the data platform to support Clinical Development and Clinical Operations, with a clear path to extend to Technical Operations, Commercial, Medical Affairs, and Finance
  • Design and oversee data ingestion, transformation, and storage for structured and semi-structured data from key Apogee sources
  • Establish and maintain subject area data models and semantic layers tailored to clinical and operational use cases
  • Ensure the platform is designed and operated in alignment with Apogee’s GxP, 21 CFR Part 11, SOX Controls, and other regulatory/compliance expectations
  • Design, build, and maintain end-to-end data pipelines (ingestion, transformation, curation) into the Data Lakehouse
  • Develop and maintain data models that serve Clinical Development, Clinical Operations, and later Tech Ops and Commercial / Med Affairs / Finance
  • Implement data quality, lineage, and metadata practices
  • Contribute to defining data governance at Apogee
  • Design and build dashboards / analytic views that support key functional area use cases
  • Define reusable data marts and semantic models that enable self-service analytics
  • Act as a trusted partner to Clinical Development, Clinical Operations, Biometrics, Medical Monitoring, and other functions
  • Work closely within IT (Infrastructure and Security), QA, and business stakeholders to support any required validation, testing, and controlled releases
  • Communicate roadmaps, status, risks, and dependencies clearly and regularly to technical and non-technical stakeholders
  • Drive adoption and literacy around the Data Lakehouse and BI tools by developing documentation, providing training/enablement for key users, and promoting best practices
  • Help define the future operating model for data and analytics at Apogee

Requirements:

  • 10+ years of experience in data engineering, data platform, or analytics roles, with meaningful experience owning or leading a modern cloud data platform (Data Lakehouse or cloud data warehouse)
  • Bachelor’s degree (or equivalent professional experience) in Life Sciences, Information Systems, Engineering, or related field
  • Proven track record as a hands-on senior level individual contributor
  • Experience with cloud-based data platforms (e.g., Databricks, Snowflake, BigQuery, or similar) and modern data stack components
  • Strong expertise in data modeling and ETL/ELT for analytics and reporting
  • Experience working closely with integration teams (ideally with MuleSoft or similar)
  • Prior experience in biotech / pharma / life sciences is strongly preferred, especially supporting Clinical Development, Clinical Operations, Biometrics, or Medical Monitoring
  • Familiarity with data from CROs and clinical systems (e.g., EDC, CTMS, safety, lab, statistical outputs)
  • Experience working in regulated environments (e.g., GxP, 21 CFR Part 11, HIPAA) and supporting audit/inspection readiness is highly desirable
  • Exposure to Apogee-relevant systems is a plus (e.g., Veeva Vault applications, Egnyte GxP repositories, SAS server, NetSuite)
  • Strong proficiency in SQL and at least one data engineering language (e.g., Python or Scala)
  • Hands-on experience with data pipeline and orchestration tools (e.g., Airflow, Azure Data Factory, dbt, or similar) and CI/CD concepts for data workloads
  • Solid understanding of data architecture patterns (data lakes, lakehouses, warehouses, dimensional modeling, semantic layers)
  • Experience integrating data from file repositories (SharePoint, Egnyte) and external partners (CROs, cloud vendors, etc.)
  • Strong understanding of data security, privacy, and access control in an enterprise setting
  • Strategic yet pragmatic
  • able to start from a greenfield environment and design a phased, realistic roadmap
  • Excellent communication and storytelling skills
  • Demonstrated ability to lead through influence
  • High ownership and bias for action, comfortable operating in a fast-paced, high-growth clinical-stage biotech environment
  • Interest in eventually building and leading a small data team
  • Ability and willingness to travel up to 20%

Nice to have:

Exposure to Apogee-relevant systems is a plus (e.g., Veeva Vault applications, Egnyte GxP repositories, SAS server, NetSuite)

What we offer:
  • Market competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, health, welfare & retirement benefits
  • Competitive time off, including three weeks PTO, two one-week company-wide shutdowns a year and dedicated paid sick leave
  • Commitment to growing you professionally and providing access to resources to further your development
  • Apogee offers regular all team, in-person meetings to build relationships and problem solve

Additional Information:

Job Posted:
January 03, 2026

Employment Type:
Fulltime
Work Type:
Remote work
Job Link Share:

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