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Clinical Research Nurse I

United States, San Antonio · Job Posted March 19, 2026
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Job Description

Clinical Research Nurse - ICON San Antonio TX- PRN M-F Day Shift. ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development. We are currently seeking a Clinical Research Nurse I to join our diverse and dynamic team. As a Clinical Research Nurse I at ICON, you will play a pivotal role in supporting the execution of clinical trials, ensuring adherence to protocol requirements, and providing compassionate patient care throughout the research process.

Job Responsibility

  • Assisting in the planning, implementation, and coordination of clinical research activities in accordance with study protocols, regulatory guidelines, and standard operating procedures (SOPs)
  • Conducting patient assessments, administering study treatments, and performing clinical procedures as required by the research protocol, while ensuring patient safety and compliance with ethical standards
  • Collecting, recording, and maintaining accurate and complete data documentation, including medical histories, vital signs, adverse events, and laboratory results, in electronic case report forms (eCRFs) and study databases
  • Collaborating with multidisciplinary teams, including investigators, study coordinators, and regulatory staff, to ensure efficient study conduct, participant recruitment, and retention throughout the duration of the trial
  • Providing education and counseling to study participants and their families regarding study procedures, treatment regimens, and informed consent, while addressing any questions or concerns that may arise during the course of the study

Requirements

  • Must hold a current and valid Registered Nurse (RN) license in the state of Texas
  • Minimum of 1-2 years of clinical nursing experience, preferably in a research or academic healthcare setting, with exposure to clinical trial operations and Good Clinical Practice (GCP) guidelines
  • Strong clinical assessment and critical thinking skills, with the ability to recognize and respond to changes in patient status and communicate effectively with healthcare professionals and study investigators
  • Knowledge of regulatory requirements governing clinical research, including the International Council for Harmonization (ICH) guidelines and local regulatory requirements, with a commitment to upholding ethical standards and patient confidentiality
  • Proficiency in electronic medical record (EMR) systems, clinical documentation, and data entry, with a high level of attention to detail and accuracy in recording patient information and study data
  • Excellent interpersonal and organizational skills, with the ability to work independently and collaboratively in a fast-paced, multidisciplinary environment, while prioritizing competing demands and meeting project deadlines

What we offer

  • Various annual leave entitlements
  • A range of health insurance offerings to suit you and your family’s needs
  • Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead
  • Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being
  • Life assurance
  • Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others
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