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Clinical Genomics Scientist, Prenatal

BillionToOne

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Location:
United States

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Category:
Research and Development

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Contract Type:
Not provided

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Salary:

126721.00 - 147841.00 USD / Year

Job Description:

BillionToOne is seeking an experienced Clinical Genomics Scientist to support variant curation and data analysis for our prenatal laboratory. This is a full-time, remote position suited for a highly skilled professional with expertise in carrier screening and a strong knowledge of CFTR, SMN1, HBB, HBA1, and HBA2.

Job Responsibility:

  • Germline Variant Curation: Conduct comprehensive reviews and classifications of newly identified variants, as well as reassess previously classified variants as needed
  • Curation Policy Development: Collaborate closely with clinical genomics scientists, laboratory directors, genetic counselors, and other stakeholders to develop and refine variant curation policies in alignment with industry best practices and society guidelines
  • Data Analysis & Interpretation: Leverage human mutation databases, functional annotation resources, and genomic browsers to facilitate accurate variant classification and reporting

Requirements:

  • Ph.D. in Human Genetics or a closely related field
  • Strong preference for candidates with experience in variant curation for carrier screening panels
  • Extensive experience in curating variants within CFTR, HBB, HBA1, and HBA2 is highly desirable
  • Proven ability to classify variants efficiently while maintaining accuracy within tight turnaround times
What we offer:
  • Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
  • Open, transparent culture that includes weekly Town Hall meetings
  • The ability to indirectly or directly change the lives of hundreds of thousands patients
  • Multiple medical benefit options
  • employee premiums paid 100% of select plans, dependents covered up to 80%
  • Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
  • Supplemental fertility benefits coverage
  • Retirement savings program including a 4% Company match
  • Increase paid time off with increased tenure
  • Latest and greatest hardware (laptop, lab equipment, facilities)
  • Generous equity options offering

Additional Information:

Job Posted:
December 26, 2025

Employment Type:
Fulltime
Work Type:
Remote work
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