Clinical Development Scientist Job at Pfizer (Marlow)

Sr. Director, Clinical Scientist

The Sr. Director, Clinical Scientist plays a pivotal role in shaping the clinica...

Location

United States , Philadelphia

Salary:

Not provided

Cabaletta Bio Inc

Expiration Date

Until further notice

Requirements

Advanced degree (MS, Ph.D., Pharm.D., M.D., or equivalent) in a relevant scientific discipline preferred
7+ years of clinical development experience within biotech, pharmaceutical, or academic settings, with demonstrated leadership in advancing programs through early and late-stage development
Cell and gene therapy experience—particularly in CAR-T or T-cell–based modalities—strongly preferred
autoimmune disease experience highly desirable
Deep understanding of T-cell biology, immunology, and translational science principles relevant to cellular therapy
Proven ability to author and critically review clinical protocols, study reports, and regulatory documents, ensuring scientific integrity and compliance with ICH-GCP and global regulatory standards
Demonstrated skill in analyzing complex clinical data, conducting literature reviews, and synthesizing insights to inform program strategy
Exceptional scientific judgment, attention to detail, and analytical rigor
Strong communication and collaboration skills, with the ability to influence and partner effectively across cross-functional teams, investigators, and external experts
Highly organized with the ability to manage multiple priorities in a fast-paced, evolving environment.

Job Responsibility

Serve as the clinical science lead for assigned CAR-T programs, partnering with the Medical Director on the design, execution, and interpretation of clinical studies across all phases of development
Author and oversee key clinical documents — including protocols, amendments, informed consent forms, investigator brochures, clinical study reports, and regulatory submissions (e.g., INDs, CTAs, DSURs, BLAs/MAAs)
Review, analyze, and interpret emerging clinical data (safety, efficacy, PK/PD) to identify trends and issues, ensuring timely resolution through cross-functional collaboration
Conduct literature and competitive landscape reviews to inform study design, data interpretation, and program strategy
Provide ongoing data review to ensure study conduct aligns with protocol, patient safety standards, and data integrity expectations
Collaborate with the Medical Monitor to ensure awareness of key safety and efficacy findings, supporting SAE review, narrative development, and safety governance activities
Lead or support governance activities, including preparation and presentation of materials for Development, Executive, and Scientific Steering Committees, as well as oversight of external boards (e.g., DSMB, adjudication committees)
Contribute to and present scientific and clinical data internally and externally (e.g., investigator meetings, scientific conferences, regulatory interactions)
Serve as the clinical science representative on cross-functional development and study teams, providing scientific and strategic input to ensure cohesive execution
Mentor study team members and contribute to vendor oversight to ensure consistency, quality, and scientific rigor across all clinical deliverables

What we offer

health and retirement, PTO, and stock option plans

Clinical Genomics Scientist, Prenatal

BillionToOne is seeking an experienced Clinical Genomics Scientist to support va...

Location

United States

Salary:

126721.00 - 147841.00 USD / Year

BillionToOne

Expiration Date

Until further notice

Requirements

Ph.D. in Human Genetics or a closely related field
Strong preference for candidates with experience in variant curation for carrier screening panels
Extensive experience in curating variants within CFTR, HBB, HBA1, and HBA2 is highly desirable
Proven ability to classify variants efficiently while maintaining accuracy within tight turnaround times

Job Responsibility

Germline Variant Curation: Conduct comprehensive reviews and classifications of newly identified variants, as well as reassess previously classified variants as needed
Curation Policy Development: Collaborate closely with clinical genomics scientists, laboratory directors, genetic counselors, and other stakeholders to develop and refine variant curation policies in alignment with industry best practices and society guidelines
Data Analysis & Interpretation: Leverage human mutation databases, functional annotation resources, and genomic browsers to facilitate accurate variant classification and reporting

What we offer

Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
Open, transparent culture that includes weekly Town Hall meetings
The ability to indirectly or directly change the lives of hundreds of thousands patients
Multiple medical benefit options
employee premiums paid 100% of select plans, dependents covered up to 80%
Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
Supplemental fertility benefits coverage
Retirement savings program including a 4% Company match
Increase paid time off with increased tenure
Latest and greatest hardware (laptop, lab equipment, facilities)

Fulltime

Reporting Clinical Laboratory Scientist

The Prenatal Reporting Clinical Laboratory Scientist (RCLS) is responsible for p...

Location

United States , Union City

Salary:

126721.00 - 172625.00 USD / Year

BillionToOne

Expiration Date

Until further notice

Requirements

Must possess an active and valid CLS or Clinical Genetic Molecular Biologist Scientist (CGMBS) license issued by the state of California
Must fulfill requirements stated in 42 CFR 493.1489 OR 493.1491
Must fulfill requirements stated in the College of American Pathologists Molecular Pathology Checklist
Working knowledge of local, state, and federal laboratory regulations required
Bachelor’s degree or equivalent in Biomedical Laboratory Sciences, Clinical Science or related field required
At least one year of Clinical Laboratory experience or equivalent high complexity and volume laboratory experience required
Experience with molecular biology techniques required
Experience with Sanger sequencing analysis, trinucleotide repeat analysis, MLPA analysis, or NGS QC preferred
Laboratory experience in molecular biology within the last year preferred
Strong computer and automation skills are preferred

Job Responsibility

Clinical Data Review, Interpretation, and Reporting: Review and interpret clinical genomics data, and sign out clinical laboratory reports, ensuring accuracy and reliability of clinical reporting
Quality Assurance: Partner with Quality Management team on QC and QA programs to maintain the highest standards in laboratory testing and reporting, ensuring adherence to CLIA, CAP, and other regulatory guidelines
Process Improvement: Identify opportunities for process optimization, efficiency enhancement, and cost-effective laboratory practices
Collaborate with Research & Development, bioinformatics and Genomic Technology team to develop, validate, and implement of new laboratory tests, methodologies, and data management and reporting systems
Team Leadership: Provide leadership and guidance to laboratory staff, including scientists, technicians, and support personnel
Collaboration: Collaborate with cross-functional teams, including Lab Operation, Customer Service, Product, Commercial, to support company goals
Analysis and Reporting (70%): Execute the bioinformatics pipelines that process and analyze raw data from samples
Manage daily test processing needs with the highest emphasis on quality
Present sample results to additional RCLSs, Laboratory Director, and/or other clinical personnel for subsequent clinical reporting
Reviewing and releasing sample reports under the purview of the Laboratory Director

What we offer

Multiple medical benefit options
employee premiums paid 100% of select plans, dependents covered up to 80%
Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
Supplemental fertility benefits coverage
Retirement savings program including a 4% Company match
Increase paid time off with increased tenure
Latest and greatest hardware (laptop, lab equipment, facilities)
Free daily on-site lunches provided from top eateries
A variety of perks on campus (state of the art gym, restaurant)
Free on-site EV charging (compatible with all EVs, including Tesla)

Fulltime

Clinical Genomics Scientist, Oncology

BillionToOne is looking for a Clinical Genomics Scientist, Oncology to help driv...

Location

United States , Menlo Park

Salary:

158401.00 - 179521.00 USD / Year

BillionToOne

Expiration Date

Until further notice

Requirements

Ph.D. in Human Genetics, M.S. in Genetic Counseling, or related field
2+ years of experience in somatic variant interpretation based on ACMG/AMP guidelines in a clinical setting (alternatively, 1+ years of germline variant interpretation and 1+ years of somatic variant interpretation experience)
Hands-on experience working with human mutation databases (COSMIC, ClinVar, OncoKB), functional annotation sources (dbSNP), and genome browsers (UCSC)
Familiarity with IGV and BAM file analysis and data-minded willingness to learn to use basic bioinformatics tools, with technically minded insights
Knowledge of cancer somatic mutation and signaling pathways (e.g., which mutations have FDA approved drugs, Phase II/III clinical trials, which mutations are considered “hot targets” for drug development, etc.)
Exceptional attention to detail to follow highly detailed SOPs and strong organizational skills to track and manage clinical reporting and product improvement projects
Excellent communication skills and ability to work collaboratively with cross-functional teams
Operationally-defined flexible schedule, including weekends, as dictated by clinical reporting needs

Job Responsibility

Somatic variant interpretation and data review: Perform somatic-based variant interpretation, diving into the literature and databases to classify variants and match treatments for reporting, performing verification as required with BAM file analysis
Clinical report drafting: Carefully draft reports for each requisition primarily using in-house reporting API, working closely with the engineering and QA teams on reporting, and the laboratory directors on report language
Somatic mutation interpretation and reporting policy development: Work closely with lab directors, R&D, medical, and other related functions to develop and modify the somatic interpretation SOPs in accordance with ACMG/AMP guidelines, and the latest published literature
Content curation: Contribute to curation of gene-level content such as domain and critical residue curation
Molecular tumor board: Serve as a subject matter expert in consulting with the medical science liaison team, and presenting in molecular tumor boards to facilitate knowledge sharing
Contribute to oncology R&D: Work closely with the R&D team to help with somatic oncology based projects, providing expertise on variant interpretation, biological pathways/mechanisms, and other gene/variant-level reviews and analyses

What we offer

Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
Open, transparent culture that includes weekly Town Hall meetings
The ability to indirectly or directly change the lives of hundreds of thousands patients
Multiple medical benefit options
employee premiums paid 100% of select plans, dependents covered up to 80%
Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
Supplemental fertility benefits coverage
Retirement savings program including a 4% Company match
Increase paid time off with increased tenure
Latest and greatest hardware (laptop, lab equipment, facilities)

Fulltime

Clinical genomic scientist

Location

Salary:

Not provided

Genome International Corp

Expiration Date

Until further notice

Requirements

5+ years’ of experience in genomics
D. in bioinformatics /Masters in Bioinformatics, Computational Biology, or Computer Science
Excellent programming skills (e.g. Python, R, Perl, Shell)
Understanding and skills in analyzing genomics data
Excellent knowledge of bioinformatics tools and databases
Aware of ACMG, NCCN, ASCO and ESMO guidelines

Job Responsibility

Design, develop and maintain bioinformatics analysis pipelines, methods, and software for analysis of clinical genomics sequencing data including reading alignment, variant calling, annotation and statistical data analysis using open source and in-house developed software
Translating and breaking down requirements from product team for the software engineers
Collaborate with software engineers for task allocation, contribute to product development by building and maintaining computational infrastructure for robust, cost-effective, and automated execution of bioinformatics pipelines in the cloud
Validating overall software output before release
Drive and collaborate with quality team for documentation needed for QMS
Responsible for quality of the software product by following best practices like code-reviews, unit test coverage and defining & adhering to single coding standard
Identify novel approaches to better and more efficiently analyze client and public data sets
Work with cross-functional teams to ensure quality throughout the bioinformatics software and analytical pipeline development life cycle

New

Global Development Product Lead

Leads multiple cross functional oncology product teams from pre-clinical candida...

Location

United States , La Jolla; Cambridge; Bothell; South San Francisco; New York City

Salary:

295900.00 - 478800.00 USD / Year

Pfizer

Expiration Date

Until further notice

Requirements

MD or MD-PhD with 10+ years of industry experience in oncology drug development is preferred, track record in oncology clinical research including early phase drug development
Clinical oncology experience: Board certification in oncology preferred
Significant industry leadership experience in clinical, translational or basic research in biomedical sciences or one of the disciplines related to drug development
Understanding of related disciplines (e.g., biostatistics, regulatory, pre-clinical pharmacology, pharmaceutical sciences)
Demonstrated scientific productivity (publications, abstracts, etc.)
Proven scientific writing skills and good communication skills
Proven leadership skills with ability to defend the clinical plan at governance meetings is essential
Capacity to adapt to a fast-paced and changing environment
Demonstrated history of effective leadership
including cross functional and matrixed teams, managing direct reports when applicable, and experience in seeking and maintaining alignment with cross-functional leaders

Job Responsibility

Leads multiple (~2-4) cross functional oncology product teams from pre-clinical candidate nomination (CAN) through Phase 1-2 clinical development and proof of concept (POC) stages
In close collaboration with functional experts on the product teams, drives the effective integration of an end-to-end cross functional molecule strategy and risk mitigation plan and ensures delivery of data-driven milestones through successful risk identification and mitigation
Support clinical trials and the development strategy for early development assets and lead development programs across multiple functions within Pfizer Oncology, as well as represent the program with the external clinical community
Develop clinical development plan from first in human clinical trial to proof-of-concept, including assessment of appropriate combinations, as well as evaluation of potential predictive and pharmacodynamics biomarker plans
To ensure the cross-functional components of the product plans including clinical expertise are provided to project teams, including medical monitoring of clinical trials
Substantial support of CDP development and diligence for external innovation activities
Lead key enterprise level cross-functional workstreams to accelerate R&D decision making
Lead, develop and execute strategic development for early development assets
Ensure timely execution and delivery of product milestones within budget
Communicate with executive management and governance committees to address program needs and provide recommendations

What we offer

Participation in Pfizer’s Global Performance Plan with a bonus target of 30.0% of the base salary
Eligibility to participate in our share based long term incentive program
401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
Paid vacation, holiday and personal days
Paid caregiver/parental and medical leave
Health benefits to include medical, prescription drug, dental and vision coverage
Relocation assistance may be available based on business needs and/or eligibility

Fulltime

New

Oncology Early-Stage Clinical Scientist

You will lead and coordinate the development of multiple studies of novel biolog...

Location

United States , Cambridge; La Jolla; Bothell; Groton; New York City

Salary:

176600.00 - 282900.00 USD / Year

Pfizer

Expiration Date

Until further notice

Requirements

Relevant PhD or PharmD and a minimum of 5 years of experience in a similar role in industry/CRO
MS and a minimum of 7 years of experience in a similar role in industry/CRO
BA/BS and a minimum of 10 years of experience in a similar role in industry/CRO
Clinical Research experience in Phase 1 in Oncology, on the side of the sponsor leading studies
Experience in or strong understanding of Oncology Drug Development especially in Early Development
Strong knowledge of clinical procedures, ICH guidelines, GCP and familiarity with FDA, EMA, and global regulations
Strong scientific writing skills and communication skills (written and verbal)
Clinical document writing experience (e.g., protocol, ICD, IB, IND), as well as understanding complex data analysis
Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations
Experience working with and solid understanding of related disciplines, e.g., Clinical Operations, Data Management, Safety, Biostatistics, Regulatory, Study Management, Pre-Clinical, Pharmacology, Quality Assurance

Job Responsibility

Partner closely with the Global Development Lead (GDL) in the execution of the clinical development strategy and plan for the assigned molecule(s)/indication(s)
Responsible for scientific leadership and execution of clinical studies and delivering on innovative clinical study designs, high quality trial execution, safety assessment and interpretation of clinical study results
Support execution for all FIH programs through proof-of concept
Set the clinical data review strategy, ensure quality data and conduct review of emerging clinical data and trends
review and query data
present and discusse relevant data to appropriate teams, governance bodies, and other internal and external stakeholders
Conduct data review, analysis and interpretation of clinical trials data together with the GDL, Clinical Safety, and Biostatistics
Serve as technical resource for clinical issues raised by internal and external collaborators, investigators, consultants and contractors
Support and assist in the development of publications, abstracts, and presentations
May sit on project teams to support clinical development implementation and contribution to key development milestones, e.g. start-up and delivery of ESoE and PoC trials

What we offer

Eligibility for participation in Pfizer’s Global Performance Plan with a bonus target of 20.0% of the base salary
Eligibility to participate in our share based long term incentive program
401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
Paid vacation, holiday and personal days
Paid caregiver/parental and medical leave
Health benefits to include medical, prescription drug, dental and vision coverage
Relocation assistance may be available based on business needs and/or eligibility

Fulltime

New

Senior Medical Director, Late Development, Breast Oncology

This position is for a Senior Medical Director within the atirmociclib program. ...

Location

United States , New York City; La Jolla; Cambridge; Bothell; Groton

Salary:

274500.00 - 444100.00 USD / Year

Pfizer

Expiration Date

Until further notice

Requirements

Medical degree with 5+ years of industry experience
Clinical oncology experience (typically 4+ years)
Board certified/eligible in oncology or equivalent preferred
Breast Oncology experience (2+ years)
Ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact
Permanent work authorization in the United States

Job Responsibility

Clinical Development Leadership on Study Teams and Development Subteams
Conduct medical monitoring activities including eligibility assessment, data review and safety monitoring
Lead peer-to-peer interactions with investigators
Serve as the point of contact for clinical issues between the study team, investigators, ethics committees, steering committees, and regulatory authorities
Lead and contribute to development and maintenance of clinical trial and regulatory documents, in collaboration with Clinical Scientist and the cross-functional team
Provide clinical development leadership across several study teams
Serve as the Clinical Development Lead on subteams including for Marketing Authorization Applications
Strategic Guidance, Clinical Insights & Interpretation
Collaborate with the Global Development Team to create and refine development strategies
Represent the company in external engagements or as committee member in joint collaborations

What we offer

Participation in Pfizer’s Global Performance Plan with a bonus target of 25.0% of the base salary
Eligibility to participate in our share based long term incentive program
401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
Paid vacation, holiday and personal days
Paid caregiver/parental and medical leave
Health benefits to include medical, prescription drug, dental and vision coverage
Relocation support available

Fulltime

Clinical Development Scientist

Pfizer

Location:
United Kingdom , Marlow

Category:
Research and Development

Contract Type:
Not provided

Salary:

Job Description:

Job Responsibility:

Requirements:

Nice to have:

Additional Information:

Job Posted:
February 20, 2026

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