CrawlJobs Logo

Clinical Biomarker Expert

sophiagenetics.com Logo

SOPHiA GENETICS

Location Icon

Location:
Switzerland; France; Germany; United Kingdom , Rolle

Category Icon

Job Type Icon

Contract Type:
Not provided

Salary Icon

Salary:

Not provided

Job Description:

You will serve as a key scientific and clinical-facing partner within our biopharma ecosystem—helping connect our clinical network with biopharma needs to shape evidence generation and multimodal real-world data initiatives. You will help "harvest" insights from the field and translate them into clear narratives and opportunities that support project development and revenue growth.

Job Responsibility:

  • Engage directly with oncologists, pathologists, and clinical stakeholders—often alongside clinical sales—to gather insights on clinically meaningful biomarkers, unmet needs, and adoption drivers
  • Support evidence generation and multimodal real-world data initiatives by helping connect biopharma questions with feasible approaches across our clinical network
  • Act as a scientific "face of credibility" in external conversations, ensuring discussions are grounded in clinical relevance and aligned to stakeholder expectations
  • Partner closely with internal teams (e.g., clinical sales, BD) to feed field intelligence back into positioning, project concepts, and customer engagement strategies
  • Contribute to revenue impact by helping identify, shape, and progress opportunities that translate clinical insights into compelling biopharma value propositions

Requirements:

  • 5 years of experience in biomarker strategy, translational medicine, medical affairs, precision oncology, companion diagnostics, or clinical evidence generation
  • Strong understanding of NGS clinical biomarkers and diagnostic concepts (IHC knowledge is a plus), with the ability to quickly learn SOPHiA GENETICS' offerings and communicate their value
  • A commercial mindset, able to connect scientific/clinical discussions to opportunity creations and revenue impact. Previous exposure to commercial conversations for an NGS Dx or CDx product highly sought
  • Strong technical knowledge combined with creativity and problem-solving skills to design and propose custom solutions tailored to client needs
  • Proven ability to engage credibly with oncologists, pathologists, KOLs, and clinical networks, and to translate clinical insights into clear, actionable business and project inputs
  • Fully fluent in English
  • additional european languages (Italian, Spanish) valuable
  • A success-orientated and solutions-focused mindset that embraces team collaborations, change, growth and inclusion

Nice to have:

  • Additional european languages (Italian, Spanish)
  • IHC knowledge
  • Previous exposure to commercial conversations for an NGS Dx or CDx product
What we offer:
  • Sickness and Accident coverage through Helsana (CH)
  • Meal Vouchers at 90CHF PM with our partner cafeteria (CH)
  • A fun and engaging work environment, with Rest & Entertainment space, full stocked free coffee machine and free fruit (CH)
  • Free parking in an easy to access location (CH)
  • A strong social committee whose purpose is to make SOPHiA GENETICs both enjoyable as well as rewarding (CH)
  • Direct interaction and exposure to senior leadership and our executive team locally (CH)
  • Forfait-Jour working types (FR)
  • Health benefits for you and your family covered by 80% employer contributions (FR)
  • Life Insurance and pensions contribution (FR)
  • SWILE meal vouchers and home office allowances (FR)

Additional Information:

Job Posted:
March 18, 2026

Employment Type:
Fulltime
Work Type:
Hybrid work
Job Link Share:

Looking for more opportunities? Search for other job offers that match your skills and interests.

Briefcase Icon

Similar Jobs for Clinical Biomarker Expert

Medical Director/Senior Medical Director, Clinical Development, Genetic Diseases

The Medical Director in Clinical Development will serve as the Medical Lead for ...
Location
Location
United States , Cambridge
Salary
Salary:
210000.00 - 375000.00 USD / Year
beamtx.com Logo
Beam Therapeutics
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • MD, DO or equivalent ex-US medical degree with 15+ years experience
  • Minimum of 4 years of Pharmaceutical/Biotech industry experience in clinical development and medical monitoring
  • Board certification/eligibility in endocrinology or metabolic disorders, or another relevant specialty highly desired
  • Strong oral and written communication skills to influence others
  • Ability to work collaboratively in a fast-paced, team-based matrix environment and to function independently as appropriate
  • Clinical development and/or clinical experience in rare disease, cell & gene therapy is a plus
  • Ability to work independently to resolve challenges
Job Responsibility
Job Responsibility
  • Serves as the Clinical Development lead on the cross-functional Program Team and co-lead the Clinical Development Sub-team for assigned programs
  • Support development of Target Product Profile (TPP) and Clinical Development Plan (CDP)
  • Serves as the medical monitor for assigned studies including design, execution and interpretation study data
  • Provides scientific and clinical input to study-related documents and analysis plans including Informed consent forms (ICF), clinical research forms (CRF), statistical analysis plans (SAP), clinical pharmacology and biomarker analysis plans
  • Ensure patient safety on clinical trials and adherence to Good Clinical Practices (GCP)
  • Contribute to the development of regulatory documents in support of regulatory submissions, including clinical section of IND's and CTA's, safety reports, responses to regulatory authorities and Ethics Committees/IRBs, and other documents as appropriate
  • Acts as liaison between Clinical Development and other internal groups at BEAM for assigned studies
  • Establishes strong collaborations with study investigators, outside medical experts and represents BEAM during investigator meetings and advisory boards
  • Contribute to the development and planning of Advisory Board meetings in the relevant therapeutic areas
  • Fulltime
Read More
Arrow Right

Clinical Quality Compliance Senior Manager

The role provides proactive end to end quality support for the development and i...
Location
Location
Türkiye , Istanbul
Salary
Salary:
Not provided
amgen.com Logo
Amgen
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Doctorate degree and 2 years of Quality Management, Quality Assurance and Good Clinical Practices experience in the pharmaceutical/biotech industry where risk-based quality management and quality by design are a core responsibility
  • Master’s degree and 4 years of the previous mentioned experience
  • Bachelor’s degree and 6 years of the previous mentioned experience
  • Associate’s degree and 10 years of the previous mentioned experience
  • Oversight and implementation of Quality Management Systems and experience managing quality in electronic QMS such as Veeva or Track wise
  • Thorough understanding of Clinical R&D activities and Global Regulations
  • Experience with Regulatory Submission and Inspection Management procedures
  • Quality Oversight of Clinical Trials, including clinical trial protocol development, execution, and submissions
  • Leadership or mentoring experience is ideal, in a regional capacity would be phenomenal
  • Excellent verbal and written communication skills, including strong business writing abilities and active listening
Job Responsibility
Job Responsibility
  • Act as a Good Clinical Practice (GCP) Subject Matter Expert, offering independent, objective quality guidance
  • Oversee quality across all clinical development stages
  • Plan and execute risk-based GCP audits (sites, affiliates, vendors, studies)
  • Support regulatory inspections and guide responses, including root cause analysis and CAPAs
  • Lead quality oversight of Risk Assessment Categorization Tools (RACT) for each trial
  • Facilitate monthly quality risk reviews with clinical program leaders
  • Manage audit findings, deviations, and CAPA responses
  • Ensure regional compliance with local regulations and support vendor evaluations
  • Analyze data quality trends, identify gaps, and implement corrective actions
  • Oversee technologies for endpoint data collection (e.g., biomarkers, imaging)
What we offer
What we offer
  • Vast opportunities to learn, develop, and move up and across our global organization
  • Diverse and inclusive community of belonging, where colleagues are empowered to bring ideas to the table, take risks, and act
  • Generous Amgen Total Rewards Plan comprising healthcare, finance, wealth and career benefits
  • Flexible work arrangements
Read More
Arrow Right

Medical Director - Clinical Development - Endocrinology and Autoimmune Diseases

AbCellera is a clinical stage biotech company developing antibody therapeutics f...
Location
Location
Canada , Vancouver
Salary
Salary:
Not provided
abcellera.com Logo
AbCellera Biologics
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • M.D. (Doctor of Medicine) or equivalent degree
  • Board Certification or eligibility in Endocrinology, Rheumatology, or Internal Medicine is preferred
  • 12+ years of clinical development and leadership experience in the pharmaceutical or biotechnology industry
  • Proven track record in the design, execution, and analysis of Phase 1-2 clinical trials
  • Excellent communication, presentation, and interpersonal skills, and are capable of influencing strategy across all levels of the organization
  • Experience with biologic agents (such as monoclonal antibodies), and/or novel modalities (bispecifics, T-cell engagers, ADC)
  • Experience interacting with major regulatory agencies (FDA, Health Canada, EMA)
  • Experience with translational medicine and biomarker development in clinical trials
Job Responsibility
Job Responsibility
  • Leading the medical strategy for assigned clinical development programs in endocrinology and/or autoimmune diseases
  • Designing and authoring clinical protocols (Phase 1-3), investigator brochures, clinical study reports (CSRs), and regulatory documents (IND, CTA)
  • Serving as the Medical Monitor for assigned trials, overseeing patient eligibility, safety, and protocol adherence
  • Interpreting clinical trial data, including safety, efficacy, and pharmacokinetics/pharmacodynamics (PK/PD), and translate findings into actionable development strategy
  • Providing medical expertise for the ongoing assessment and management of patient safety, including reviewing cumulative safety data, serious adverse events (SAEs) and contributing to safety reports (DSURs)
  • Ensuring all clinical development activities are conducted in accordance with Good Clinical Practice (GCP), relevant regulatory requirements, and company standard operating procedures (SOPs)
  • Serving as the primary clinical contact for assigned programs to internal teams, external investigators, and regulatory agencies
  • Establishing and maintaining collaborative relationship with medical experts and investigators in the assigned therapeutic areas of development
  • Collaborating closely with cross-functional teams, including Translational Science, Clinical Operations, Regulatory Affairs, Biostatistics, and Corporate Development
  • Developing publications, present data and strategy to governance committees and at external meetings
What we offer
What we offer
  • Equity
  • Annual bonus dependent on team and company performance
  • 6% (non-match) RRSP contribution
  • CAD $1,500 annual Active Lifestyle Allowance
  • Annual vacation
  • Professional development opportunities
  • Comprehensive health benefits
  • Scientific and technical mentorship
  • Fulltime
Read More
Arrow Right

Medical Director, Experimental Medicine

Fully remote role, US based candidates only. BioMarin’s EXPERIMENTAL MEDICINE te...
Location
Location
United States
Salary
Salary:
228500.00 - 310000.00 USD / Year
biomarin.com Logo
BioMarin Pharmaceutical
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • MD required
  • MD/PhD preferred
  • Ability to work collaboratively in a matrixed, fast-paced environment
  • Interest and curiosity in development challenges
  • Effective and impactful in cross-functional team structure
  • Excellent communication skills, with a desire to develop strong internal and external collaborations
Job Responsibility
Job Responsibility
  • As a member of preclinical project teams, inform preclinical experimental plans for in vitro and in vivo pharmacology and toxicology packages
  • Develop biomarker strategy for preclinical assets and inform execution of experiments to inform their downstream clinical usage in advance of asset entry to the clinic
  • Formulate clinical development plans that serve as the strategic basis for full clinical development of an asset, with particular emphasis on demonstrating proof of mechanism in first in human and first in patient clinical trials as well as subsequent demonstration of proof of concept in the clinic
  • Serve as clinical development team lead for assets in the research phase through Phase 1 clinical trial study completion
  • Lead clinical contributions to pre-IND and IND submissions (and other stage-appropriate Regulatory submissions)
  • Lead clinical contributions to Phase 1 study protocols and trial-related documents
  • Design and execute natural history studies that enable (1) deepened understanding of proposed targeted patient populations and (2) development of endpoints that enable efficient demonstration of POC and/or approval
  • Serve as clinical expert to aid new project identification (both on internal new programs and business development opportunities)
  • Represent Experimental Medicine in scientific advisory and academic meetings
  • Serve as Medical Monitor on BioMarin clinical trials
What we offer
What we offer
  • company-sponsored medical, dental, vision, and life insurance plans
  • paid time off
  • discretionary annual bonus
  • discretionary stock-based long-term incentives
  • Fulltime
Read More
Arrow Right

Medical Director, Experimental Medicine

BioMarin’s Experimental Medicine team is seeking an experienced Medical Director...
Location
Location
United States
Salary
Salary:
228500.00 - 300000.00 USD / Year
biomarin.com Logo
BioMarin Pharmaceutical
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • MD or MD/PhD required
  • Significant demonstrated experience with IND filings and Phase 1 trial clinical leadership (5+ years of hands-on experience in industry clinical trials)
  • Demonstrated experience in Phase 1 clinical trials in industry (within pharmaceutical and/or biotech companies, CROs, or Phase 1 trial units)
  • Experience leading clinical development teams
  • Experience with clinical development plans
  • Ability to work collaboratively in a matrixed, fast-paced environment
  • Interest and curiosity in development challenges
  • Effective and impactful in cross-functional team structure
  • Excellent communication skills, with a desire to develop strong internal and external collaborations
Job Responsibility
Job Responsibility
  • Formulate clinical development plans that serve as the strategic basis for full clinical development of an asset
  • Serve as clinical development team lead for assets in the research phase through Phase 1 clinical trial study completion
  • Lead clinical contributions to pre-IND and IND submissions (and other stage-appropriate Regulatory submissions)
  • Lead clinical contributions to Phase 1 study protocols and trial-related documents
  • Serve as Medical Monitor on Phase 1 trials
  • Design and execute natural history studies
  • Partner with Biomarker colleagues to ensure patient selection, pharmacodynamic, response, and approval endpoint development plans are in place for each asset
  • Serve as clinical expert to aid new project identification (both on internal new programs and business development opportunities)
  • Represent Experimental Medicine in scientific advisory and academic meetings
What we offer
What we offer
  • Discretionary annual bonus
  • Discretionary stock-based long-term incentives
  • Paid time off
  • Company-sponsored medical, dental, vision, and life insurance plans
  • Fulltime
Read More
Arrow Right

Global Development Product Lead

Leads multiple cross functional oncology product teams from pre-clinical candida...
Location
Location
United States , La Jolla; Cambridge; Bothell; South San Francisco; New York City
Salary
Salary:
295900.00 - 478800.00 USD / Year
pfizer.de Logo
Pfizer
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • MD or MD-PhD with 10+ years of industry experience in oncology drug development is preferred, track record in oncology clinical research including early phase drug development
  • Clinical oncology experience: Board certification in oncology preferred
  • Significant industry leadership experience in clinical, translational or basic research in biomedical sciences or one of the disciplines related to drug development
  • Understanding of related disciplines (e.g., biostatistics, regulatory, pre-clinical pharmacology, pharmaceutical sciences)
  • Demonstrated scientific productivity (publications, abstracts, etc.)
  • Proven scientific writing skills and good communication skills
  • Proven leadership skills with ability to defend the clinical plan at governance meetings is essential
  • Capacity to adapt to a fast-paced and changing environment
  • Demonstrated history of effective leadership
  • including cross functional and matrixed teams, managing direct reports when applicable, and experience in seeking and maintaining alignment with cross-functional leaders
Job Responsibility
Job Responsibility
  • Leads multiple (~2-4) cross functional oncology product teams from pre-clinical candidate nomination (CAN) through Phase 1-2 clinical development and proof of concept (POC) stages
  • In close collaboration with functional experts on the product teams, drives the effective integration of an end-to-end cross functional molecule strategy and risk mitigation plan and ensures delivery of data-driven milestones through successful risk identification and mitigation
  • Support clinical trials and the development strategy for early development assets and lead development programs across multiple functions within Pfizer Oncology, as well as represent the program with the external clinical community
  • Develop clinical development plan from first in human clinical trial to proof-of-concept, including assessment of appropriate combinations, as well as evaluation of potential predictive and pharmacodynamics biomarker plans
  • To ensure the cross-functional components of the product plans including clinical expertise are provided to project teams, including medical monitoring of clinical trials
  • Substantial support of CDP development and diligence for external innovation activities
  • Lead key enterprise level cross-functional workstreams to accelerate R&D decision making
  • Lead, develop and execute strategic development for early development assets
  • Ensure timely execution and delivery of product milestones within budget
  • Communicate with executive management and governance committees to address program needs and provide recommendations
What we offer
What we offer
  • Participation in Pfizer’s Global Performance Plan with a bonus target of 30.0% of the base salary
  • Eligibility to participate in our share based long term incentive program
  • 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
  • Paid vacation, holiday and personal days
  • Paid caregiver/parental and medical leave
  • Health benefits to include medical, prescription drug, dental and vision coverage
  • Relocation assistance may be available based on business needs and/or eligibility
  • Fulltime
Read More
Arrow Right

Oncology Early-Stage Clinical Scientist

You will lead and coordinate the development of multiple studies of novel biolog...
Location
Location
United States , Cambridge; La Jolla; Bothell; Groton; New York City
Salary
Salary:
176600.00 - 282900.00 USD / Year
pfizer.de Logo
Pfizer
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Relevant PhD or PharmD and a minimum of 5 years of experience in a similar role in industry/CRO
  • MS and a minimum of 7 years of experience in a similar role in industry/CRO
  • BA/BS and a minimum of 10 years of experience in a similar role in industry/CRO
  • Clinical Research experience in Phase 1 in Oncology, on the side of the sponsor leading studies
  • Experience in or strong understanding of Oncology Drug Development especially in Early Development
  • Strong knowledge of clinical procedures, ICH guidelines, GCP and familiarity with FDA, EMA, and global regulations
  • Strong scientific writing skills and communication skills (written and verbal)
  • Clinical document writing experience (e.g., protocol, ICD, IB, IND), as well as understanding complex data analysis
  • Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations
  • Experience working with and solid understanding of related disciplines, e.g., Clinical Operations, Data Management, Safety, Biostatistics, Regulatory, Study Management, Pre-Clinical, Pharmacology, Quality Assurance
Job Responsibility
Job Responsibility
  • Partner closely with the Global Development Lead (GDL) in the execution of the clinical development strategy and plan for the assigned molecule(s)/indication(s)
  • Responsible for scientific leadership and execution of clinical studies and delivering on innovative clinical study designs, high quality trial execution, safety assessment and interpretation of clinical study results
  • Support execution for all FIH programs through proof-of concept
  • Set the clinical data review strategy, ensure quality data and conduct review of emerging clinical data and trends
  • review and query data
  • present and discusse relevant data to appropriate teams, governance bodies, and other internal and external stakeholders
  • Conduct data review, analysis and interpretation of clinical trials data together with the GDL, Clinical Safety, and Biostatistics
  • Serve as technical resource for clinical issues raised by internal and external collaborators, investigators, consultants and contractors
  • Support and assist in the development of publications, abstracts, and presentations
  • May sit on project teams to support clinical development implementation and contribution to key development milestones, e.g. start-up and delivery of ESoE and PoC trials
What we offer
What we offer
  • Eligibility for participation in Pfizer’s Global Performance Plan with a bonus target of 20.0% of the base salary
  • Eligibility to participate in our share based long term incentive program
  • 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
  • Paid vacation, holiday and personal days
  • Paid caregiver/parental and medical leave
  • Health benefits to include medical, prescription drug, dental and vision coverage
  • Relocation assistance may be available based on business needs and/or eligibility
  • Fulltime
Read More
Arrow Right
New

Data Engineer Specialist

We are seeking an experienced Data Engineering Specialist with strong hands-on e...
Location
Location
India , Pune
Salary
Salary:
Not provided
vodafone.com Logo
Vodafone
Expiration Date
Until further notice
Flip Icon
Requirements
Requirements
  • Strong expertise in Databricks on GCP including Delta Lake, notebooks/jobs, Unity Catalog, and cluster policies
  • Experienced in Cloud Data Fusion design, including pipeline management, error handling, and orchestration
  • Skilled in Dataproc Spark with experience building PySpark jobs, configuring ephemeral clusters, and handling initialisation actions
  • Proficient in Python for data engineering including packaging, unit testing, type hints, and linting
  • Strong SQL skills, specifically with BigQuery including performance tuning, partitioning, and clustering
  • Familiar with GCP services such as Cloud Storage, Pub/Sub, and Cloud Composer/Airflow
  • Holds a qualification such as B.E., B.Tech, BCA, MCA, BSc, or MSc in Computer Science or a related field
Job Responsibility
Job Responsibility
  • Design and build data pipelines on GCP using Databricks (Delta Lake and Unity Catalog) for orchestration, Dataproc for Spark execution, supporting both ETL/ELT and feature engineering workloads
  • Engineer declarative, modular, and reusable pipelines in Python, following configuration-as-code principles and CI/CD practices including Git-based promotion, testing, and deployment
  • Implement and maintain data quality and observability practices using validation frameworks, logging, metrics, and alerts
  • Optimise pipeline performance, reliability, and cost through techniques such as cluster sizing, auto-termination, Z-ordering, caching, and partitioning strategies
  • Apply robust error handling, parameterisation, and triggers within Cloud Data Fusion pipelines
  • Ensure operational excellence by maintaining monitoring, performance tuning, and continuous improvements across data products and workloads
What we offer
What we offer
  • The opportunity to build and scale data solutions using leading GCP and Databricks technologies
  • Exposure to enterprise-level CI/CD, observability, and configuration-as-code practices
  • A collaborative environment where innovation, continuous learning, and technical excellence are encouraged
  • The chance to contribute to high-impact global data platforms
Read More
Arrow Right