Bioconjugation Scientist Job at Piper Companies (Philadelphia)

Msat Scientist I - Bioconjugation

Proclinical is seeking an MSAT Scientist I - Bioconjugation to support the trans...

Location

United States , Bristol

Salary:

Not provided

Proclinical

Expiration Date

Until further notice

Requirements

Degree in Biochemistry, Chemical Engineering, Pharmaceutical Sciences, or related field
Basic understanding of cGMP manufacturing environments
Exposure to bioconjugation processes such as ADCs or AOCs preferred but not required
Familiarity with purification techniques like TFF and chromatography (Protein A, IEX, HIC) is a plus
Understanding of aseptic techniques and single-use systems is advantageous
Strong attention to detail and documentation practices
Ability to follow technical instructions and adapt quickly in a fast-paced environment
Basic data analysis skills using Excel or similar tools
Effective communication skills and ability to work in cross-functional teams
Preferred experience with high-potency APIs, process validation, PPQ, and commercial tech transfer

Job Responsibility

Adhere to cGMP, GDP, GLP, FDA, and ICH requirements and internal procedures
Support technology transfer activities from Process Development or external partners into manufacturing, including document review and execution readiness
Assist in authoring and revising batch records, SOPs, BOMs, and other GMP documentation
Provide on-the-floor manufacturing support during batch execution, including troubleshooting under supervision
Contribute to deviation investigations, root cause analysis, and CAPA implementation with guidance from senior staff
Collect, trend, and analyze data to support process performance and continuous improvement
Participate in process characterization and scale-up activities
Support preparation and execution of PPQ and validation activities as assigned
Maintain knowledge of raw materials, consumables, and single-use assemblies used in manufacturing
Assist in developing training materials and updating process documentation

Fulltime

Process Development Senior Scientist - Synthetic Peptides, Oligonucleotides, ADCs

Join Amgen’s Mission of Serving Patients. At Amgen, if you feel like you’re part...

Location

United States , Thousand Oaks

Salary:

126066.05 - 170559.95 USD / Year

Amgen

Expiration Date

Until further notice

Requirements

Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable]
OR Master’s degree and 3 years of Scientific experience
OR Bachelor’s degree and 5 years of Scientific experience

Job Responsibility

Work effectively with a diverse team of synthetic chemists, chemical engineers and analytical chemists to invent synthetic routes and develop safe, robust, sustainable and cost-effective processes for antibody drug conjugate, peptide antibody conjugates, synthetic peptides and/or oligonucleotide manufacturing
Drive technology innovation in the synthesis, purification, and characterization of bioconjugates, oligonucleotides, and/or synthetic peptides
Support cGMP manufacturing and technology transfer to our internal manufacturing facilities and external contract manufacturers
Advance enabling technologies to accelerate pharmaceutical development and to improve sustainability and process efficiency
Ensure process performance through process understanding, modeling and characterization
Contribute to drug substance development teams by providing experimental results, technical updates, documentation, data interpretation, recommendations, etc
Work cross-functionally to deliver regulatory documents and support regulatory filings
Serve as a technical expert and keep current in the field of bioconjugation, antibody drug conjugate, oligonucleotide, peptide, and process chemistry and manufacturing
Work independently in advancing projects and studies within required deadlines

What we offer

Health and welfare plans for staff and eligible dependents
Financial plans with opportunities to save towards retirement or other goals
Work/life balance
Career development opportunities
Retirement and Savings Plan with generous company contributions
Group medical, dental and vision coverage
Life and disability insurance
Flexible spending accounts
Discretionary annual bonus program
Stock-based long-term incentives

Fulltime

Associate Scientist, Process Sciences

Drive innovation at the bench by helping shape next‑generation siRNA therapeutic...

Location

United States , Cambridge

Salary:

34.00 - 44.00 USD / Hour

Proclinical

Expiration Date

Until further notice

Requirements

BS in Chemistry, Chemical Engineering, Biochemistry, or a related scientific discipline
0-2 years of laboratory experience (academic, co-op, internship, or industrial experience acceptable)
Oligonucleotide experience required
Experience with Bioconjugation, antibodies, and peptides highly preferred
Familiarity with analytical techniques such as pH, conductivity, HPLC, or LC-MS is preferred
Strong attention to detail and commitment to high-quality laboratory documentation
Willingness to learn regulated laboratory practices and manufacturing workflows
Ability to work collaboratively, follow instructions, and manage time effectively
Microsoft Office Suite experience

Job Responsibility

Support process development, optimization, and scale-up of bioconjugation processes
Support oligonucleotide synthesis method development, optimization and scale-up
Execute laboratory-scale processes to support research and in-house material needs
Perform routine in-process analytical tests (e.g., pH, conductivity, UV, basic chromatography)
Assist in process development for novel chemistries
Operate laboratory and analytical equipment after appropriate training
Accurately document experimental work following good documentation practices (GDP)
Collaborate with cross-functional teams including Process Development, Analytical Sciences, and Manufacturing
Maintain a safe, organized, and compliant laboratory workspace

Associate Scientist, Process Sciences

Drive innovation at the bench by helping shape next‑generation siRNA therapeutic...

Location

United States , Cambridge

Salary:

34.00 - 44.00 USD / Hour

Proclinical

Expiration Date

Until further notice

Requirements

BS in Chemistry, Chemical Engineering, Biochemistry, or a related scientific discipline
0-2 years of laboratory experience (academic, co-op, internship, or industrial experience acceptable)
Oligonucleotide experience required
Experience with Bioconjugation, antibodies, and peptides highly preferred
Familiarity with analytical techniques such as pH, conductivity, HPLC, or LC-MS is preferred
Strong attention to detail and commitment to high-quality laboratory documentation
Willingness to learn regulated laboratory practices and manufacturing workflows
Ability to work collaboratively, follow instructions, and manage time effectively
Microsoft Office Suite experience

Job Responsibility

Support process development, optimization, and scale-up of bioconjugation processes
Support oligonucleotide synthesis method development, optimization and scale-up
Execute laboratory-scale processes to support research and in-house material needs
Perform routine in-process analytical tests (e.g., pH, conductivity, UV, basic chromatography)
Assist in process development for novel chemistries
Operate laboratory and analytical equipment after appropriate training
Accurately document experimental work following good documentation practices (GDP)
Collaborate with cross-functional teams including Process Development, Analytical Sciences, and Manufacturing
Maintain a safe, organized, and compliant laboratory workspace

Principal Scientist/Senior Scientist Nucleic Acid Delivery

We are looking for a passionate and innovative Scientist in the field of Nucleic...

Location

United States , Cambridge

Salary:

Not provided

Evonik Industries

Expiration Date

Until further notice

Requirements

Ph.D. and 4+ or 8+ years (M.Sc.) of relevant industry experience in LNP development and drug delivery with a strong background in nucleic acid therapeutics and education in a related discipline (Pharmaceutical Sciences, Biomedical Engineering, Biochemistry, etc.)
Strong theoretical and practical knowledge of lipid-based and polymer-based delivery systems, manufacturing technologies, and hands-on experience in nanoparticle characterization techniques (e.g., DLS, zeta potential, ribogreen, pKa, chromatography)
Knowledge of formulation downstream purification methods such as ultrafiltration and tangential flow filtration (TFF)
Knowledge of lipid chemistry and bioconjugation techniques
Knowledge of cell-based assays for evaluating the performance and mechanism of action of novel delivery systems
Familiarity with gel electrophoresis for nucleic acid and protein characterization
Ability to work in a biosafety level 2 environment
Experience in setting up and operating high-throughput screening protocols for delivery formulations
Knowledge of formulation or assay automation, including lab automation equipment setup, programming, and the application of machine learning approaches
Proven ability to independently interpret experimental data, troubleshoot technical challenges, and develop innovative solutions

Job Responsibility

Lead the design, development, and characterization of novel non-viral vector platforms for targeted delivery of nucleic acid-based therapeutics, including lipid nanoparticles and alternative gene delivery systems
Establish relevant in vitro assays and conduct high-throughput in vitro experiments to evaluate the efficacy and safety of developed formulations in traditional and advanced cell culture models
Engage with customers to understand their needs and execute feasibility projects
Collaborate with cross-functional teams to define project scopes, timelines, and deliverables based on market needs and internal capabilities, while taking a leadership role in project management
Identify and evaluate emerging technologies in nucleic acid delivery, contributing to the strategic direction of research initiatives and leading efforts to integrate these technologies into ongoing projects
Document research findings and present results to internal stakeholders and at scientific conferences, fostering a culture of innovation within the team and promoting the dissemination of knowledge
Mentor junior scientists, technicians and students, providing guidance and support in their professional development, and leading training sessions to enhance team capabilities
Engage with external partners in academia and industry to enhance collaborative efforts and knowledge exchange, including leading initiatives to establish new partnerships and collaborations
Stay abreast of industry trends and scientific advancements, integrating relevant findings into ongoing research and development efforts

What we offer

performance-based remuneration
occupational health benefits
hybrid and flexible working environments with #SmartWork
attractive career paths
high-quality development programs

Fulltime

New

Operations Chemist

As an Operations Chemist at FCC Environment, you will be responsible for the che...

Location

United Kingdom , Knottingley

Salary:

28527.00 - 35659.00 GBP / Year

Webrecruit

Expiration Date

Until further notice

Requirements

Degree in Chemistry (or similar) or a minimum of an HND in Chemistry or a related subject
Experience of waste, wastewater or water analysis using spectrophotometric methods
Knowledge of hazardous waste classification and consignment systems (desirable)
Good working knowledge of Microsoft Office
Ability to work both independently and as part of a small team
Strong communication skills and confidence in liaising with stakeholders
Flexible approach to work, including overtime when required
Good problem-solving skills and ability to use initiative

Job Responsibility

Inspect and analyse packaged waste received for processing
Oversee waste processing, undertake analysis as required, and maintain accurate records
Carry out waste processing operations
Load and unload vehicles using a forklift truck
Provide support to WTD clients/customers by listing, segregating, and labelling packaged chemical waste on their premises as required
Provide the necessary information to ensure chemical waste can be transported safely in accordance with current legislation
Ensure all labels and transport documentation, including waste lists where appropriate, are accurate, available, and compliant with current legislation
Safely transport packaged chemical waste, as required, to permitted waste disposal sites in accordance with instructions from the Commercial Team
Assist WTD drivers, as necessary, with the labelling and segregation of their loads
Support the Sales Team, as required, by sampling incoming and outgoing loads

What we offer

Competitive salary
25 days’ annual leave (full-time) plus Bank Holidays
Pension scheme
Life insurance
Discretionary bonus scheme
On-the-job training and progression
Recognition scheme
Refer a friend scheme
Flexible benefits, including high street savings, cycle to work scheme and Gymflex membership
Access to an Employee Assistance Programme and Best Doctors Service via our Wellbeing Platform

Fulltime

New

Sr Analyst, HR

As Senior HR Analyst you play a meaningful role in delivering data-driven HR ins...

Location

Mexico , Ciudad de México

Salary:

Not provided

Baxter

Expiration Date

Until further notice

Requirements

Bachelor's degree or equivalent experience in organizational psychology, human resources or similar
3 years of experience in Human Resources operations and strategy
Lead and organize cultural activities to promote brand engagement within the team
Participate in compensation reviews, work environment and labor relations activities
Experience in global companies working with international teams

Job Responsibility

Support the area in the implementation of Human Resources plans and programs, such as Talent Review and Planning, Annual Compensation Review, performance management, and overall global and cluster HR strategy
Serve as a point of contact for handling employee-related data and information, including report generation and data analysis
Work independently to effectively resolve all HR-related matters
Recommend, develop, and improve HR systems, policies, and processes
Appropriately bring up any situations or issues related to HR matters
Responsible for managing cultural and engagement activities across all locations
Ensure job descriptions are kept up to date and follow up on company training plans in coordination with the Quality department
Responsible for analyzing key HR performance indicators

Fulltime

New

Programme Manager - Cat Friendly Homing

Our client works to improve the welfare and understanding of animals. They are n...

Location

United Kingdom

Salary:

42000.00 GBP / Year

Webrecruit

Expiration Date

July 09, 2026

Requirements

Proven exceptional project management experience, including delivery of complex programmes
A strong understanding of cat health, behaviour and wellbeing
Excellent communication, organisational and stakeholder management skills
The ability to work independently and build relationships across an international network
A qualification or significant experience in veterinary medicine, veterinary nursing, animal welfare, clinical behaviour or a related field

Job Responsibility

Lead the development and delivery of a key programme, helping organisations around the world improve welfare outcomes for unowned cats through coaching, training and accreditation
Managing international projects
Oversee the coaching programme and support a global network of coaches, learners and stakeholders to deliver high-quality learning initiatives
Drive the development of resources, training materials and an accreditation scheme
Monitor programme impact, manage budgets and identify opportunities for continuous improvement
Liaise with funders, providing updates, case studies and feedback
Produce content for newsletters and support webinars, blogs, forums, podcasts and other promotional activities
Develop programme resources, guidance and promotional materials
Represent the programme at internal and external meetings, events and working groups
Build and maintain relationships with international stakeholders

What we offer

25 days’ annual leave plus bank holidays, rising to 28 days after 2 years, 30 days after 5 years
Enhanced maternity and paternity leave
Employee assistance programme
Access to personalised coaching

Fulltime

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Bioconjugation Scientist

Job Description

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