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Associate Scientist, Process Sciences

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Proclinical

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Location:
United States , Cambridge

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Contract Type:
Not provided

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Salary:

34.00 - 44.00 USD / Hour

Job Description:

Drive innovation at the bench by helping shape next‑generation siRNA therapeutics through hands‑on process development. Proclinical is seeking a motivated Associate Scientist to join the Process Sciences group, supporting the process development to incorporate novel chemistries into our manufacturing platform for siRNA therapeutics. This entry-level role is ideal for a recent graduate or early-career scientist looking to gain hands-on experience in processing, manufacturing, and process development of oligonucleotide therapeutics within a collaborative, fast-paced environment.

Job Responsibility:

  • Support process development, optimization, and scale-up of bioconjugation processes
  • Support oligonucleotide synthesis method development, optimization and scale-up
  • Execute laboratory-scale processes to support research and in-house material needs
  • Perform routine in-process analytical tests (e.g., pH, conductivity, UV, basic chromatography)
  • Assist in process development for novel chemistries
  • Operate laboratory and analytical equipment after appropriate training
  • Accurately document experimental work following good documentation practices (GDP)
  • Collaborate with cross-functional teams including Process Development, Analytical Sciences, and Manufacturing
  • Maintain a safe, organized, and compliant laboratory workspace

Requirements:

  • BS in Chemistry, Chemical Engineering, Biochemistry, or a related scientific discipline
  • 0-2 years of laboratory experience (academic, co-op, internship, or industrial experience acceptable)
  • Oligonucleotide experience required
  • Experience with Bioconjugation, antibodies, and peptides highly preferred
  • Familiarity with analytical techniques such as pH, conductivity, HPLC, or LC-MS is preferred
  • Strong attention to detail and commitment to high-quality laboratory documentation
  • Willingness to learn regulated laboratory practices and manufacturing workflows
  • Ability to work collaboratively, follow instructions, and manage time effectively
  • Microsoft Office Suite experience

Nice to have:

  • Experience with Bioconjugation, antibodies, and peptides
  • Familiarity with analytical techniques such as pH, conductivity, HPLC, or LC-MS

Additional Information:

Job Posted:
March 25, 2026

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