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For a Company in Ghent we are looking for a (junior) Associate Scientist to join the DSP team.
Job Responsibility:
CMC-grade research batch purifications to deliver NANOBODY® batches
Development of DSP processes for NANOBODY® pre-candidates during pre-clinical development
Large-scale DSP activities (purification of tens to thousands of grams), including in-house production of non-GMP (Good Manufacturing Practise) DS (Drug Substance) for toxicology studies
DSP-related activities to support late-stage projects
DSP platform improvement and new Technology exploration
Uses state-of-the-art equipment (AKTA, Sartorius, TECAN) and diverse types of columns and membrane chromatography (affinity, Ion Exchange, Hydrophobic Interaction, mixed mode) and filtration (µ- filtration and ultrafiltration TFF (Tangential Flow Filtration), depth filtration) techniques to perform generic and developability purifications (mg to multi-gram scale range) in a timely manner with eye for quality
Reports about the results and progress to the line and/or project supervisor, project team and project leader
Prepares experimental reports (eLN), meeting summaries/presentations and drafts working protocols in English
Requirements:
Have a degree B. Sc., M. Sc. Biotechnology/(Bio)chemistry/Pharmacology/Industrial engineer or equivalent field, or a proven track record within biotechnology
Have excellent communication skills (fluent in English, written and spoken as English is the official communication language)
Have knowledge of Word, PowerPoint, and Excel and some knowledge of electronic Lab notebook reporting (Benchling is a plus)
Have sense for initiative, quality, and accuracy
Have the ability and desire to work in a fast-paced, dynamic environment
Be a team player, enthusiastic and flexible.
Nice to have:
Having prior experience in purification of NANOBODY® molecules is a plus but not mandatory