Associate Scientist (Clinical Assay) Job at Pfizer (Pearl River)

Associate Scientist - Clinical Immunology

At Pfizer, our purpose is to deliver breakthroughs that transform patients' live...

Location

United States , Pearl River

Salary:

60200.00 - 97500.00 USD / Year

Pfizer

Expiration Date

Until further notice

Requirements

BA/BS in Science with 0 - 2 years of relevant experience
Strong attention to detail
Ability to collaborate and work effectively in a team environment as well as independently
Proficiency in computer skills, including word processing, Excel, PowerPoint, and relevant scientific software
Experience in developing and troubleshooting bioassays designed to assess antibody functionality
Experience with mammalian cells and aseptic techniques

Job Responsibility

Conduct biofunctional immunological assays to support vaccine clinical development, adhering to Good Clinical Laboratory Practice (GCLP) requirements
Maintain a detailed inventory of freezer reagents, including controls, proficiency panels, toxins, and reference standards
Collect, analyze, and critically review clinical and nonclinical data to support assay development, sample analysis, troubleshooting, qualification, and other laboratory projects, and present progress to colleagues and senior management
Execute sample testing and analysis for toxicology and clinical trials, and provide critical review of resulting clinical and nonclinical data
Build team skills and collaborate effectively within the work group
Stay current on all departmental and corporate training
Organize work to meet deadlines and apply technical skills
Follow procedures for assigned tasks and seek guidance when necessary

What we offer

401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
paid vacation, holiday and personal days
paid caregiver/parental and medical leave
health benefits to include medical, prescription drug, dental and vision coverage
participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary
Relocation assistance may be available

Fulltime

Associate Scientist, Translational Medicine

This role is located in Center City, Philadelphia and is primarily a lab-focused...

Location

United States , Philadelphia

Salary:

Not provided

Cabaletta Bio Inc

Expiration Date

Until further notice

Requirements

MS degree in Biology or Bioengineering (or related field) with 2+ years of experience, or Bachelor's degree with 4+ years of experience in the biotechnology industry required
Proficiency in flow cytometry and flow cytometry data analysis (using FlowJo or equivalent software) is required
General lab skills, including aseptic techniques and human tissue handling required
Must be highly organized and able to work independently in a fast-paced environment
Must be able to clearly communicate in writing, must have a desire to be part of a growing organization that uses cutting-edge science
A high level of flexibility to support various other activities and the ability to learn new techniques outside of existing field of expertise
Strong team orientation and passion for continuous self-development

Job Responsibility

Perform and support the development of laboratory assays on clinical (and potentially pre-clinical) samples to generate translational data that informs safety, biological activity, and therapeutic impact of rese-cel
Manage clinical sample processing, accessioning, tracking, and lifecycle documentation with careful attention to metadata and data integrity
Maintain accurate, GDP-compliant experimental records using electronic laboratory notebooks (ELN) and sample management systems
Document all procedures and experimental parameters within our ELN and follow up with Quality Control/Assurance for review. Address and document any QA concerns and participate in root-cause assessments and CAPAs if necessary
Contribute to assay development, qualification, and validation efforts and assist in the preparation of related SOPs
Manage multiple internal projects and collaborate cross-functionally with Translational, Pre-clinical, and Analytical Sciences teams, as well as external partners
Perform laboratory activities in accordance with GLP/cGLP standards, company safety policies, and SOPs, including general maintenance of laboratory space
Other related duties, as assigned

What we offer

health and retirement, PTO, and stock option plans

Senior Research Associate- Diagnostic Assay Development

10x Genomics is establishing a diagnostics effort, translating our leading singl...

Location

United States , Pleasanton

Salary:

97700.00 - 132100.00 USD / Year

10x Genomics

Expiration Date

Until further notice

Requirements

B.S. or M.S. in Molecular Biology, Genetics, Biochemistry, or a related scientific field
B.S. with 5+ years or M.S. with 3+ years of hands-on experience in molecular diagnostics or genomics assay development in an industry setting
Direct, demonstrable experience with advanced molecular technologies, particularly Next-Generation Sequencing (NGS) workflows
Exceptional proficiency in molecular biology techniques, including nucleic acid extraction, PCR/qPCR, and NGS library preparation
A proven track-record of using and optimizing and troubleshooting molecular biology protocols
Experience working with challenging clinical sample types (e.g., FFPE tissue, primary tumor cells, low-input samples)
Experience working within a quality system or environment governed by CLIA, CAP, or ISO 13485 standards strongly preferred
Prior hands-on experience with 10x Genomics single-cell or spatial technologies (e.g., Chromium or Xenium platforms) is a strong advantage
Experience with automated liquid handling for high-throughput assay execution is a strong advantage
experience with microscopy techniques a plus

Job Responsibility

Hands-on execution of complex single-cell and spatial genomics assays (e.g., sample processing, library preparation, sequencing)
Systematically troubleshoot, optimize, and refine specific steps within the assay workflow to improve performance, robustness, and efficiency
Perform feasibility studies on new reagents, instrumentation, and process improvements for clinical readiness
Prepare and process samples in support of large-scale clinical research studies
Generate and maintain meticulous laboratory records, protocols (SOPs), and batch records following Good Documentation Practices (GDP)
Execute formal experiments for analytical validation studies, including assessment of accuracy, precision, limit of detection, and reproducibility
Ensure all work is conducted under appropriate quality controls
Present experimental data clearly and concisely in team meetings and written reports
Support the transfer of robust assay workflows to the CLIA operations team
Collaborate closely with R&D Scientists, Automation Engineers, and Bioinformatics teams to meet project milestones

What we offer

Equity grants
Comprehensive health and retirement benefit programs
Annual bonus program or sales incentive program
Health Package
Easy-to-use Benefits
Family oriented
Generous Time Off

Fulltime

Research Associate II (Pre-clinical)

The Research Associate II (Pre-clinical) supports laboratory research experiment...

Location

United States , Rockville

Salary:

55000.00 - 65000.00 USD / Year

THE GENEVA FOUNDATION

Expiration Date

Until further notice

Requirements

Master’s degree in a relevant scientific discipline (e.g., biology, chemistry, biomedical engineering) required
4–6 years' experience in laboratory research
Ability to exercise independent judgment in fast-paced research environments with strict deadlines
Ability to multi-task
Demonstrated competence in oral and written communication
Must be organized, attentive to detail, and possess a positive and professional demeanor
Must possess eligibility to work in the U.S. Visa sponsorship not provided.

Job Responsibility

Analyze and interpret scientific data
Lead the development of technical documentation
Support the training of junior scientific staff
Effectively communicate results to a broad range of experts and stakeholders
Execute research studies (under the direction of the project's Principal Investigator or Research Scientist), manage study documentation, and prepare progress reports
Interact and communicate effectively with Principal Investigator, other site personnel, and The Geneva Foundation personnel
Procure supplies and equipment as authorized per research budget guidelines
Assist with interim and annual reports
Actively participate in regular team meetings
Complete required and applicable research training needed to complete research

What we offer

medical, dental, and vision healthcare
Flexible Spending Account
Health Savings account, with employer contribution
Coverage is provided for employees and family members including domestic partners
Short-and long-term disability
Employee Assistance Program
Life & ADD insurance
403b retirement plan with generous employer match
flexible leave options
11 paid holidays per year

Fulltime

Principal Scientist, Immunology

We are seeking a highly accomplished and motivated Principal Scientist with a Ph...

Location

China , Beijing

Salary:

400000.00 - 600000.00 CNY / Year

Randstad

Expiration Date

August 24, 2026

Requirements

PhD degree in Immunology, Molecular Immunology, Cellular Immunology, or a closely related biomedical science discipline, with formal specialized training in immunology
A minimum of 6 years of full-time professional working experience in biotech, pharmaceutical, or related life sciences industry, with proven track record in immunology research and assay development
Advanced proficiency in flow cytometry: multi-color panel design, instrument operation for both conventional and spectral flow cytometer, data acquisition, high-dimensional immune cell phenotyping, and functional immune cell analysis for diverse primary immune cell populations
Immune cell profiling using a range of other techniques including ELISpot, ELISA, MSD, Western Blot and PCR
Extensive experience in all stages of pharmacodynamic (PD) assay development, optimization, validation, and data analysis for preclinical and clinical research
Hands-on experience in primary lymphoid and myeloid immune cell subset isolation/purification using positive and negative selection strategies, culture, stimulation, and functional characterization from human and animal samples
Design, develop, validate and implement complicated co-culture suppression and killing assays in 2D or 3D in vitro cellular model systems using primary immune cells and immortal cell lines under sterile conditions
Development, evaluation and implementation of new technologies as required by the projects
Proven aseptic technique, attention to detail and acts independently to determine methods and procedures on new or special assignments
Deep and up-to-date scientific knowledge of cellular and molecular immunology, immune system regulation, immune cell function, and therapeutic modulation of immune responses

Job Responsibility

Design, execute, and troubleshoot complex immunological experiments, analyze large-scale flow cytometry and PD assay data using specialized software and interpret results to generate data-driven scientific conclusions and actionable recommendations
Apply advanced flow cytometry techniques to perform comprehensive profiling, phenotyping, and functional analysis of various primary immune cell subsets (including T cells, B cells, NK cells, monocytes, macrophages, dendritic cells, granulocytes, and other innate/adaptive immune cell populations) from preclinical animal models, human peripheral blood, and tissues samples
Provide technical mentorship and scientific training to junior scientists, research associates, and lab technicians on flow cytometry operations, immune cell isolation/handling, and PD assay methodologies
establish and standardize SOPs for immunology assays to ensure data accuracy, reproducibility, and lab efficiency
Collaborate cross-functionally with drug discovery, preclinical development, clinical research, analytical development, and regulatory teams to align immunology strategies with overall program milestones, and support study design for preclinical and clinical trials
Prepare detailed scientific reports, study protocols, and regulatory documentation
present research findings to internal leadership, cross-functional teams, and external partners
contribute to scientific publications, conference presentations, and patent applications

Fulltime

Scientist, Process Development

Reporting to the Associate Principal Scientist, Process Development, the Scienti...

Location

United States , Philadelphia

Salary:

Not provided

Cabaletta Bio Inc

Expiration Date

Until further notice

Requirements

Bachelor’s Degree with 4+ years of experience, or Master’s Degree with 2+ years of experience, within biologics process development and manufacturing under cGMP processes
Experience with cell therapy manufacturing scale-up, technology transfer, and process development methods is required
Experience with basic biological laboratory techniques such as cell culture, PCR, cell-based bioassays, and/or ELISA
Extensive experience in flow cytometry and cell-based assays is required
Strong problem-solving skills are preferred
Experience supporting regulatory documentation, including but not limited to INDs, CTAs, and BLAs
Previous experience and working knowledge of T-cells or immunological cell therapies
Good working knowledge of cGMP manufacturing for biological processes and ICH regulations
Highly organized and efficient, with a curiosity for cutting-edge science
Strong team orientation and a passion for continuous self-development

Job Responsibility

Design and execute process development experimental plans, author associated protocols and reports, and present data and insights to cross-functional teams
Develop phase-appropriate cell therapy manufacturing processes using Quality by Design (QbD) principles
Support technology transfer of processes to CDMOs for early-phase cGMP clinical manufacturing, as needed
Contribute to the development of platform manufacturing processes and ensure readiness for clinical and future commercial manufacturing
Identify and evaluate opportunities to improve manufacturing performance, including cost, throughput, robustness, and quality
Maintain laboratory materials and sample inventory to support experimental planning and execution
Accurately document experimental data in a timely manner, ensuring data integrity, traceability, and compliance with protocols
Maintain individual training requirements in a compliant state
Contribute to regulatory filings (e.g., IND/CTA) and technical documentation, as needed
Other related duties, as assigned

What we offer

health and retirement
PTO
stock option plans

Fulltime

Manager, Process Development and Automation

The Manager, Process Development and Automation provides leadership support to t...

Location

United States , Redwood City

Salary:

124000.00 - 200000.00 USD / Year

Exact Sciences

Expiration Date

Until further notice

Requirements

Bachelor's Degree in Engineering, Technology, Molecular Biology, Clinical Laboratory science, Chemical, biological, Electronics, or related field and 2 years’ experience as outlined in the essential duties
or Associates Degree in a Microbiology field or Engineering Science and 4 years’ experience as outlined in the essential duties in lieu of Bachelor's degree
2+ years in a role with progressively increasing responsibilities such as laboratory management, quality and control, lead technologist, or technical specialist
8+ years’ experience in process development, laboratory automation, service engineering, laboratory setting, or related industry as outlined in the essential duties
Successful track record of leading projects holistically from inception to successful implementation with cross-functional participation in a matrixed environment
Proficient in computer aided design software (SolidWorks) or statistical analysis programs (JMP), Microsoft Office Word, Excel, PowerPoint, and similar software
Working knowledge of regulatory requirements to make sure the laboratory is in compliance with all applicable laws and regulations, including applicable CLIA, CAP, California, New York (CLEP), and other requirements
Experience in the design, development, and implementation of solutions comprised of integrated automated and manual workflows, including software components in a highly regulated environment (ISO 13485 or 21 CFR Part 820, or cGMP using 21 CFR Part 210, 21 CFR Part 211)
Understanding and application of user requirements, system requirements, risk assessments, trace matrices, FMEA, etc. translating into a successful track record in understanding complex end-user applications, collecting and clearly documenting end-user needs, and translating those into clear, concise, and testable requirements
1+ years in a leadership role with staff and team accountability

Job Responsibility

Provide leadership on best practices for the development of processes and products in a regulated environment
Lead the team in continuous improvement projects and support other areas’ needs dependent on demand
Coach, mentor, and raise the team's ability to deliver and exceed expectations while creating opportunities for team member development
Consistent demonstration of exceptional leadership qualities
Effectively manage, support, and guide your team
Serve as a resource for employees by sharing and knowledge transfer of best practices for experiment design and execution
Ensure that any incoming support requests from outside of the normal channels are properly routed
Ensure that assigned support requests from cross-functional project teams or business units are being actively addressed
Assist and coordinate training methodology and training documentation in conjunction with other leadership
Provide mentoring and technical guidance to PDA engineers and scientists

What we offer

Paid time off (including days for vacation, holidays, volunteering, and personal time)
Paid leave for parents and caregivers
A retirement savings plan
Wellness support
Health benefits including medical, prescription drug, dental, and vision coverage
Bonus eligibility

Fulltime

Reagent Development Scientist II

Client Biosciences is a world leader in bringing innovative diagnostic and resea...

Location

United States , San Jose

Salary:

28.00 - 32.00 USD / Hour

MillenniumSoft Inc

Expiration Date

Until further notice

Requirements

Experience with bench work
BS degree in Biology with Immunology as one of the subjects
analytical thinking and experience in MS Office
Experience in writing protocols, reports, and manufacturing documentation such as work instructions, SOPs, and manufacturing specifications
Experienced in bench-testing and has effective analytical and problem-solving skills
M.S. in Biology, Immunology, Biomedical engineering and other Biological majors
Knowledge of or demonstrated interest in immunology, hematology and/or clinical chemistry in the clinical, research and pharmaceutical environment
Lab skills, including pipetting, working with blood, cells or other sample types
Knowledge of general laboratory safety, GMP’s, and associated regulatory requirements
Minimum B.S. degree in Biology, Immunology, Biomedical engineering and other Biological majors

Job Responsibility

hands-on laboratory testing
basic flow cytometry workflows to assist in new assays and reagents development
preparation of biological samples
analysis of flow cytometry data
preparation of documentation
test method development/process validation studies
provide support for technology transfer of products and processes from R&D into operations
performing work under supervision of a project lead who will define deliverables
participate in project team meetings
be responsible for documenting and presenting findings

Fulltime

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Associate Scientist (Clinical Assay)

Job Description

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