Associate Research Scientist Job at jobRxiv

Associate Research Scientist

The Division of Science is looking to hire an Associate Research Scientist to he...

Location

United States , Waltham

Salary:

82000.00 USD / Year

Brandeis University

Expiration Date

Until further notice

Requirements

PhD in Biology or other related disciplines required
1-3 years of relevant experience required
Experience working with other lab members to effectively drive projects and manuscripts forward to help build the overall scientific strengths and interests of the lab
Must have prior experience working with model systems and questions that this lab is interested in to be able to effectively contribute to the requirements for this position

Job Responsibility

Administers major projects related to developing a CRISPR screening pipeline in mammalian cells
Contribute to ongoing projects in S.pombe through intellectual or technical contributions
Contribute to grants and manuscripts through critical feedback or experiments
Assist with specifically assigned lab management tasks
Mentor or train graduate students as needed

Fulltime

Associate Research Scientist – Protein Mass Spectrometry

We are looking for a highly motivated Associate Research Scientist with demonstr...

Location

Canada , Vancouver

Salary:

61600.00 - 77000.00 CAD / Year

AbCellera Biologics

Expiration Date

Until further notice

Requirements

MSc in Analytical Chemistry, Biochemistry, or a related field, or a BSc with 3+ years of relevant wet lab experience in an academic or industry setting
Hands on experience preparing and analyzing organic compounds, metabolites, or other ADC-related small molecules using LC-MS workflows
Experience with analytical and scientific software such as Chromeleon, TraceFinder, Compound Discoverer, ChemDraw, Prism
Hands on experience operating LC-MS instrumentation including QQQ, Q-TOF, or Orbitrap MS systems
Able to implement methods for high throughput sample preparation and automated data analysis, and have experience in method qualifications and drafting SOPs
Experience with other small molecule analytical techniques such as NMR or IR Spectroscopy
Think critically, are curious, and want to explore new technologies and opportunities to improve antibody characterization workflows and processes
Creative problem solver and fast learner who believes in team work to tackle the most challenging scientific problems
Great interpersonal skills, and thrive in a collaborative working environment as a member of cross-functional team
Excellent documentation, organizational, and communication skills, impeccable attention to detail, and an ability to analyse and interpret large datasets

Job Responsibility

Performing LC-MS methods for quantitation and characterization of small molecule compounds and/or antibodies or other proteins
Evaluating and recording performance metrics for LC-MS platforms and assays
Documenting results in an ELN and communicating across a matrix team
Assisting with various analytical laboratory activities, including compound inventory, LC-MS instrument operation, maintenance, and troubleshooting
Assisting with assay development, including method validation and optimization
Performing routine and advanced bioanalytical assays to support in vitro activities
Developing and implementing standard operating procedures
Organizing, supporting, and collaborating with team members to meet project deliverables and timelines

What we offer

Equity
Annual bonus dependent on team and company performance
6% (non-match) RRSP contribution
CAD $1,500 annual Active Lifestyle Allowance
Annual vacation
Professional development opportunities
Comprehensive health benefits
Scientific and technical mentorship

Fulltime

New

Senior Clinical Research Associate/Clinical Research Associate II - Oncology

As a Clinical Research Associate (CRA) at Parexel, you act as an integral part t...

Location

United States

Salary:

Not provided

Parexel

Expiration Date

Until further notice

Requirements

Minimum 3 years relevant experience in clinical research site monitoring (preferably 2 years in Oncology) in a CRO or pharma organization
Preferred therapeutic experience in Oncology
Global clinical trial experience preferred
Extensive knowledge of clinical trial methodologies, ICH/GCP, Food and Drug Administration (FDA) and local country regulations
Must be fluent in English and in the native language(s) of the country they will work in
Travel (60-80%) within area is required
Valid driver’s license and passport required
Demonstrated knowledge of clinical research and development processes and ability to gain command of process details
Demonstrated knowledge of global and local regulatory requirements
Demonstrated understanding of key operational elements of clinical research (e.g., monitoring, data acquisition and cleaning, reporting, etc.)

Job Responsibility

Ensure proper conduct of clinical trials in accordance with the Study Monitoring Plan (SMP) and applicable prevailing laws, GCP, and sponsor standards to achieve project goals, timelines and quality
Manage assigned operational aspects for implementation of clinical trial activities at assigned investigator sites from site activation through to database lock, ensuring relevant timelines and quality deliverables are met
During study conduct, serve as the primary point of contact for assigned investigator sites
Work in partnership with and/or escalate to the SCP to ensure quality of site delivery
Interface with the study team as needed, facilitate information flow between members of the study team, vendors and assigned investigator sites
Partner with SCP to perform investigator site development, coaching and training of site personnel to ensure ongoing compliance with protocol and the safeguarding of patients
Provide protocol training to, and address protocol related questions from the investigator site staff when required, including discussions on known/anticipated operational and clinical trial risks
Attend investigator meeting when required (virtual or F2F)
Provide enrollment support and ensure progress by responding to site activation and recruitment issues from investigators
Partner with SCP and the study team to define and support recruitment initiatives at site level

What we offer

Flexible work arrangements
Career growth and development
Supportive and inclusive environment
Diverse therapeutic areas and project exposure
Advanced Technology

Fulltime

Research Scientist Gcm - Oral Medicine Translational Research Laboratories

The Research Scientist is responsible for conducting basic and clinical translat...

Location

United States , Charlotte

Salary:

47.50 - 71.25 USD / Hour

Advocate Aurora Health

Expiration Date

Until further notice

Requirements

MD and/or Ph.D. with at least 3 years of relevant post-doctoral research in biochemistry, molecular biology, cell biology, or relevant biomedical fields preferred
Published in respected journals with high report factors preferred
Experience in biostatistics, bioinformatics, basic and translational research in oral Medicine preferred

Job Responsibility

Performs searches in bioreository, genomic and bioinformatic databases, analyzes data, and prepares presentations
Provides instruction and mentors to residents, post-doctoral fellows, students and research associates on the fundamentals of Oral Medicine Research, evidence-based medicine, research principles, and methodologies
Develops and Performs basic science and clinical translational research projects related, but not limited, to oral medicine, cancer, and autoimmune diseases
Collaborates on projects on the basic and clinical and translational aspects of oral medicine
Generates data quality check, data reports and analysis and writes progress reports
Writes manuscripts for publication in peer-reviewed journals
Prepares abstracts and presents research findings at local and national meetings
Conceives, develops, writes, and submits grant funding
Participates in safety and quality assurance activities

What we offer

Paid Time Off programs
Health and welfare benefits such as medical, dental, vision, life, and Short- and Long-Term Disability
Flexible Spending Accounts for eligible health care and dependent care expenses
Family benefits such as adoption assistance and paid parental leave
Defined contribution retirement plans with employer match and other financial wellness programs
Educational Assistance Program

Fulltime

Research Scientist GCM - Oral Medicine Translational Research Laboratories

The Research Scientist is responsible for conducting basic and clinical translat...

Location

United States , Charlotte

Salary:

47.50 - 71.25 USD / Hour

Advocate Health Care

Expiration Date

Until further notice

Requirements

MD and/or Ph.D. with at least 3 years of relevant post-doctoral research in biochemistry, molecular biology, cell biology, or relevant biomedical fields preferred
Published in respected journals with high report factors preferred
Experience in biostatistics, bioinformatics, basic and translational research in oral Medicine preferred

Job Responsibility

Performs searches in biorepository, genomic and bioinformatic databases, analyzes data, and prepares presentations
Provides instruction and mentors to residents, post-doctoral fellows, students and research associates on the fundamentals of Oral Medicine Research, evidence-based medicine, research principles, and methodologies
Develops and Performs basic science and clinical translational research projects related, but not limited, to oral medicine, cancer, and autoimmune diseases
Collaborates on projects on the basic and clinical and translational aspects of oral medicine
Generates data quality check, data reports and analysis and writes progress reports
Writes manuscripts for publication in peer-reviewed journals
Prepares abstracts and presents research findings at local and national meetings
Conceives, develops, writes, and submits grant funding
Participates in safety and quality assurance activities

What we offer

Paid Time Off programs
Health and welfare benefits such as medical, dental, vision, life, and Short- and Long-Term Disability
Flexible Spending Accounts for eligible health care and dependent care expenses
Family benefits such as adoption assistance and paid parental leave
Defined contribution retirement plans with employer match and other financial wellness programs
Educational Assistance Program
Premium pay such as shift, on call, and more based on a teammate's job
Incentive pay for select positions
Opportunity for annual increases based on performance

Fulltime

New

Associate Scientist II, R&D, Complex Product Development

This is where new knowledge is discovered. Baxter’s Research and Development tea...

Location

India , Ahmedabad

Salary:

Not provided

Baxter

Expiration Date

Until further notice

Requirements

Master's in science with 8 to 12 years of Experience
Good experience in the execution of analytical method development, validation and technology transfer and routine analysis for peptides and iron colloidal drug products for regulatory submission
Competency with method relevant to iron DS/DP analysis, including particle size distribution by gel filtration chromatography, light scattering/diffraction/obscuration methods, assay of various iron forms, e.g. ferrous, ferric, labile iron, chelation assays, reduction potential and kinetics, etc, is strongly desired
Basic Knowledge and execution of Chemical Analysis using techniques relevant to complex injectables
Knowledge of pharmacopoeia, ICH Guidelines
Execution of Operational and Calibration of Instrument on periodic basis
Trouble shooting of various problems obtain during the during analysis
Knowledge of Transfer of Technology
Knowledge of Good Laboratory Practice and Good Documentation Practices
Communication skills

Job Responsibility

To plan and perform sample analysis (analytical method development, validation, technology transfer, etc) activity following GxP & GDP practices for regulatory submissions for complex injectables like peptides, iron formulations, etc
Assist in regulatory query responses for Complex Products
To perform testing of Complex Injectable samples, including, API, development, validation, stability, bulk hold, RLD, PDR and any other samples as required, according to appropriate method of analysis
To be competent in analytical problem-solving, focus on innovation, process improvement and operational excellence
To keep track of all activities related to product analysis, ensure completion in the stipulated time, and inform the Sub-department manager if any deviation or issues observed
Preparation and review of analytical reports, SOPs and MOAs by referring to GQP & current pharmacopoeia as per requirement
To carry out all testing and data recording according to the approved SOPs following GDP & ALCOA++ principles and current pharmacopoeia
To use appropriate reference and working standards for analysis and maintain their records
To complete all training as per the quality matrix targets
To perform or review the calibration records of instruments as per approved SOPs

What we offer

Support for Parents
Continuing Education/ Professional Development
Employee Heath & Well-Being Benefits
Paid Time Off
2 Days a Year to Volunteer

Fulltime

New

Senior Research Associate- Diagnostic Assay Development

10x Genomics is establishing a diagnostics effort, translating our leading singl...

Location

United States , Pleasanton

Salary:

97700.00 - 132100.00 USD / Year

10x Genomics

Expiration Date

Until further notice

Requirements

B.S. or M.S. in Molecular Biology, Genetics, Biochemistry, or a related scientific field
B.S. with 5+ years or M.S. with 3+ years of hands-on experience in molecular diagnostics or genomics assay development in an industry setting
Direct, demonstrable experience with advanced molecular technologies, particularly Next-Generation Sequencing (NGS) workflows
Exceptional proficiency in molecular biology techniques, including nucleic acid extraction, PCR/qPCR, and NGS library preparation
A proven track-record of using and optimizing and troubleshooting molecular biology protocols
Experience working with challenging clinical sample types (e.g., FFPE tissue, primary tumor cells, low-input samples)
Experience working within a quality system or environment governed by CLIA, CAP, or ISO 13485 standards strongly preferred
Prior hands-on experience with 10x Genomics single-cell or spatial technologies (e.g., Chromium or Xenium platforms) is a strong advantage
Experience with automated liquid handling for high-throughput assay execution is a strong advantage
experience with microscopy techniques a plus

Job Responsibility

Hands-on execution of complex single-cell and spatial genomics assays (e.g., sample processing, library preparation, sequencing)
Systematically troubleshoot, optimize, and refine specific steps within the assay workflow to improve performance, robustness, and efficiency
Perform feasibility studies on new reagents, instrumentation, and process improvements for clinical readiness
Prepare and process samples in support of large-scale clinical research studies
Generate and maintain meticulous laboratory records, protocols (SOPs), and batch records following Good Documentation Practices (GDP)
Execute formal experiments for analytical validation studies, including assessment of accuracy, precision, limit of detection, and reproducibility
Ensure all work is conducted under appropriate quality controls
Present experimental data clearly and concisely in team meetings and written reports
Support the transfer of robust assay workflows to the CLIA operations team
Collaborate closely with R&D Scientists, Automation Engineers, and Bioinformatics teams to meet project milestones

What we offer

Equity grants
Comprehensive health and retirement benefit programs
Annual bonus program or sales incentive program
Health Package
Easy-to-use Benefits
Family oriented
Generous Time Off

Fulltime

Clinical Scientist Associate Director – Late Development, Oncology

Join Amgen's Mission of Serving Patients. At Amgen, if you feel like you're part...

Location

Portugal , Lisbon

Salary:

79656.90 - 107771.10 EUR / Year

Amgen

Expiration Date

Until further notice

Requirements

Doctorate degree and 3 years of life sciences/healthcare experience
Master's degree and 5 years of life sciences/healthcare experience
Bachelor's degree and 7 years of life sciences/healthcare experience

Job Responsibility

Support set up and execution of late phase clinical trials with a focus on data quality
Assist in authoring clinical protocols, Investigators Brochures and other regulatory documents ensuring consistency and clarity
Provide input into and implementation of data management plan, CRF design, and data review oversight
Support review, analysis, and presentation preparation of clinical trial data for internal decision making, external interactions, and regulatory submission
Assists the management of collaborators, consultants, and/or Clinical Research Organizations in completion of key projects
Anticipate and actively manage problems across a broad spectrum of cross-functional teams
Work cross-functionally within teams to ensure clinical strategy is translated into the development of the study concept document, study protocol and related documents
Support appropriate training, recruitment, and development requirements for matrix team resources

What we offer

Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
Discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models, including remote and hybrid work arrangements, where possible

Fulltime

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Associate Research Scientist

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Associate Research Scientist

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