Associate Research Scientist – Protein Mass Spectrometry

• Performing LC-MS methods for quantitation and characterization of small molecule compounds and/or antibodies or other proteins
• Evaluating and recording performance metrics for LC-MS platforms and assays
• Documenting results in an ELN and communicating across a matrix team
• Assisting with various analytical laboratory activities, including compound inventory, LC-MS instrument operation, maintenance, and troubleshooting
• Assisting with assay development, including method validation and optimization
• Performing routine and advanced bioanalytical assays to support in vitro activities
• Developing and implementing standard operating procedures
• Organizing, supporting, and collaborating with team members to meet project deliverables and timelines

• MSc in Analytical Chemistry, Biochemistry, or a related field, or a BSc with 3+ years of relevant wet lab experience in an academic or industry setting
• Hands on experience preparing and analyzing organic compounds, metabolites, or other ADC-related small molecules using LC-MS workflows
• Experience with analytical and scientific software such as Chromeleon, TraceFinder, Compound Discoverer, ChemDraw, Prism
• Hands on experience operating LC-MS instrumentation including QQQ, Q-TOF, or Orbitrap MS systems
• Able to implement methods for high throughput sample preparation and automated data analysis, and have experience in method qualifications and drafting SOPs
• Experience with other small molecule analytical techniques such as NMR or IR Spectroscopy
• Think critically, are curious, and want to explore new technologies and opportunities to improve antibody characterization workflows and processes
• Creative problem solver and fast learner who believes in team work to tackle the most challenging scientific problems
• Great interpersonal skills, and thrive in a collaborative working environment as a member of cross-functional team
• Excellent documentation, organizational, and communication skills, impeccable attention to detail, and an ability to analyse and interpret large datasets

Familiarity with large molecule analytical techniques such as UHPLC, CE-SDS, SEC-MALLS, DLS, or icIEF

• Equity
• Annual bonus dependent on team and company performance
• 6% (non-match) RRSP contribution
• CAD $1,500 annual Active Lifestyle Allowance
• Annual vacation
• Professional development opportunities
• Comprehensive health benefits
• Scientific and technical mentorship