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System Director Jobs

20 Job Offers

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Associate Director, Solution Enablement (System Owner) - Business Enablement
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Canada
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Not provided
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Parexel
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System Director Payer Strategy
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United States , Englewood
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80.17 - 119.26 USD / Hour
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American Nursing Care
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Director, Delivery System Engagement (DSE) Network Optimization Program Management
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Director, Delivery System Engagement Network Optimization Program Management leads strategic provider network initiatives in New York, driving OON performance through data synthesis and cross-functional alignment. Requires 8+ years in healthcare strategy or network management, with expertise in d...
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United States , New York
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127500.00 - 236555.00 USD / Year
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Healthfirst
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Director, Delivery System Innovation
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United States , New York
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127500.00 - 236555.00 USD / Year
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Healthfirst
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Senior Director, GTM & System Integration Advisory
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Senior Director, GTM & System Integration Advisory at NTT DATA—a leadership role driving insurance transformation. Requires 15+ years in P&C/L&A insurance, GTM strategy, and system integration expertise. Remote US position offering $160K–$296K, plus comprehensive benefits including 401k match. Id...
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United States of America , Remote
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160000.00 - 296000.00 USD / Year
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NTT DATA
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System Director of Research
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Seeking a BC/BE Emergency Medicine physician with a Texas license to serve as System Director of Research in Dallas. You will lead system-wide research initiatives, secure external funding, and collaborate with the BSW Research Institute. This role offers comprehensive benefits, a generous CME al...
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United States , Dallas
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Not provided
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Integrative Emergency Services
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System Director, Regulatory Affairs and Accreditation
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Lead regulatory and accreditation strategy for a major health system in Charleston. Ensure compliance with TJC, CMS, and DHEC standards while managing a professional team. This director role requires 9+ years of experience, including 4 years in management, to drive operational excellence and qual...
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United States , Charleston
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MUSC Health
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System Level Architect Director
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Lead global system architecture for complex hardware-software ecosystems as a Director. Define end-to-end architecture, ensure scalability, and align platforms with business strategy. This senior role in Troy, USA, requires 10+ years of experience architecting integrated global products and offer...
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United States , Troy
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152000.00 - 220000.00 USD / Year
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Aptiv plc
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Enterprise Operating System Director
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Lead the global Enterprise Operating System (EOS) program in Troy, USA. You will drive operational strategy, document consolidation, and lean methodology across four key workstreams. This senior role offers comprehensive benefits, requiring strong leadership in cross-functional collaboration and ...
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United States , Troy
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Aptiv plc
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Director, Power Transmission System & Strategy
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Lead Microsoft's global power transmission strategy, shaping grid codes and energy policy for sustainable datacenter growth. You will manage a team of experts and build key relationships with utilities, ISOs, and regulatory bodies like NERC. This senior role requires deep experience in grid code ...
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United States
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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System architect director
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Lead digital transformation as a System Architect Director in Tokyo. Design high-availability cloud architectures on Azure and optimize large-scale infrastructure. You will need 5+ years of cloud delivery experience, fluency in Japanese, and leadership of multinational teams. Enjoy a competitive ...
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Japan , Tokyo
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8000000.00 - 15000000.00 JPY / Year
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Randstad
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Program Director System Simulation Education
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Lead the strategic development and standardization of simulation-based education across CHRISTUS Health. This visionary role requires a Master's degree and 5+ years in healthcare simulation, curriculum design, and faculty development. You will ensure evidence-based practices to enhance clinical c...
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United States , Irving
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CHRISTUS Health
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System Director, Accreditation & Regulatory Affairs
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Lead accreditation and regulatory strategy for Duke University Health System. This senior role requires a master's degree and 5+ years' expertise in healthcare compliance, guiding a team to ensure continuous readiness for The Joint Commission and CMS. Based in Durham, it's a key leadership positi...
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United States , Durham
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Kirby Bates Associates
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System Director, Emergency Services
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Lead emergency nursing across a four-hospital system as the System Director of Emergency Services. This Springfield-based role requires a master's in nursing and five years of ED leadership experience. You will set clinical standards, drive strategic priorities, and ensure excellence in patient c...
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United States , Springfield
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Kirby Bates Associates
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Director – System Nursing Informatics
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Lead nursing informatics strategy at Aspirus Health in Wausau. This director role bridges clinical care and technology, optimizing Epic EHR workflows to enhance patient safety and quality. Requires a Master's in Nursing/Informatics, 5+ years clinical experience, and 3+ years in informatics leader...
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United States , Wausau
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Kirby Bates Associates
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Director, System Clinical Quality and Risk Management
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Lead system-wide clinical quality, risk management, and patient safety initiatives at Aspirus. This director-level role in Wausau requires a Master’s degree and 5+ years in quality/risk data analysis with leadership experience. You will develop strategic goals, ensure regulatory compliance, and d...
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United States , Wausau
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Kirby Bates Associates
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Director, System Care Coordination
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Lead system-wide care coordination strategy at Aspirus Health in Wausau. This director role requires a Master's degree and 5+ years of leadership in care coordination or utilization review. You will oversee a multidisciplinary team to ensure seamless care transitions and drive strategic health sy...
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United States , Wausau
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Kirby Bates Associates
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System Director Real Estate Project Delivery
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Lead the transformation of healthcare project delivery in the South Region. This senior role requires 10+ years of leadership in healthcare facilities, capital management, and real estate. You will build a high-performance team, implement innovative processes, and manage a full capital portfolio....
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United States , Englewood
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85.61 - 127.35 USD / Hour
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American Nursing Care
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System Director, Professional Billing
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Lead the professional billing operations for a major health system. This director role requires 7+ years of revenue cycle management, Epic expertise, and multi-specialty group experience. You will oversee daily operations, compliance, and A/R for sites in Vermont and New York. A key finance team ...
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United States , South Burlington
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67.24 - 100.86 USD / Hour
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The University of Vermont Health Network
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System Director, Patient Access
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Lead strategic design and operations for front-end revenue cycle functions at UVMH. This director role requires 10+ years of healthcare management and Epic experience. You will ensure financial, patient care, and experience objectives are met through enterprise-wide solutions. Based in South Burl...
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United States , South Burlington
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67.24 - 100.86 USD / Hour
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The University of Vermont Health Network
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About the System Director role

System Director jobs represent a high-impact leadership role at the intersection of technology, business strategy, and operational excellence. Professionals in this field are responsible for overseeing the design, implementation, and optimization of complex information systems that support an organization’s core functions. Unlike traditional IT management, System Director roles demand a strategic mindset that aligns technical infrastructure with long-term business goals, ensuring that technology investments deliver measurable value.

Typical responsibilities for System Director jobs include defining the overall system architecture and roadmap, managing cross-functional teams of engineers, analysts, and project managers, and establishing governance frameworks for data quality, security, and compliance. These leaders act as the bridge between technical departments and executive leadership, translating business needs into technology requirements and vice versa. They oversee system integrations, data warehousing, and analytics platforms, often leading migrations from legacy systems to modern cloud-based solutions. A significant portion of the role involves stakeholder management—working with department heads, vendors, and external partners to prioritize features, resolve issues, and ensure user adoption. System Directors also drive continuous improvement by evaluating emerging technologies, conducting return-on-investment analyses, and championing innovation initiatives that enhance operational efficiency.

The skills required for System Director jobs are both broad and deep. On the technical side, candidates typically need extensive experience with enterprise software (such as ERP, CRM, or clinical trial management systems), data analytics tools (like Power BI or Tableau), and cloud platforms (Azure, AWS, or GCP). Proficiency in SQL, data modeling, and system integration is essential. Equally important are soft skills: exceptional communication, the ability to simplify complex concepts for non-technical audiences, and a collaborative approach to working in matrixed environments. System Directors must be adept at managing competing priorities, building business cases, and fostering a culture of data-driven decision-making. A bachelor’s degree in computer science, information systems, or a related field is common, with many roles requiring 7–10 years of progressive experience, including 3–5 years in a leadership capacity.

System Director jobs are found across industries—healthcare, finance, education, manufacturing, and technology—each with its own regulatory and operational nuances. The common thread is the need for leaders who can balance tactical execution with strategic vision, ensuring that systems not only run smoothly but also propel the organization forward. For professionals seeking System Director jobs, the role offers a unique opportunity to shape how an entire enterprise leverages data and technology, making it a career path for those who thrive on complexity, collaboration, and measurable impact.