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Sr. System Engineer Jobs

11 Job Offers

Sr. System Engineer-MANO
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Seeking a Sr. System Engineer-MANO in Mexico City to lead enterprise IAM and cybersecurity initiatives. Requires 5-7 years of experience with Active Directory, Azure/Entra, and advanced PowerShell automation. Key responsibilities include designing RBAC, O365 Exchange administration, and vulnerabi...
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Mexico , Mexico City
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Not provided
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Tech Mahindra
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Sr. Linux System Administrator/System Engineer
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Senior Linux System Administrator / Systems Engineer needed for a mission-critical IC environment in Annapolis Junction. Requires 10+ years of RHEL/CentOS expertise, JBoss/WildFly, VMware, and scripting (Shell/Python). Multiple shifts available, including weekends. Benefits include free dental/vi...
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United States , Annapolis Junction
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Not provided
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Columbia Technology Partners
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Sr. Connectivity system engineer
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Sr. Connectivity System Engineer sought for an on-site role in Shanghai, China, with up to 50% travel to Liuzhou. You will ensure GM’s Onstar solution integrates seamlessly into export vehicles from local partners. Requires 5-15 years of telematics experience, deep knowledge of wireless technolog...
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Location
China , Shanghai
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Not provided
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General Motors
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Sr. Engineer - Reliability System Owner (Drug Substance Ops)
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Amgen seeks a Sr. Engineer - Reliability System Owner for Drug Substance Ops in Juncos, US. You will own the lifecycle and performance of critical equipment, leveraging FMEA and predictive maintenance. Requires a Doctorate or Master’s in Engineering with experience in reliability and root cause a...
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United States of America , Juncos
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Not provided
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Amgen
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Sr Engineer - Warehouse Management System
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Seeking a Sr Engineer for Warehouse Management Systems in Atlanta. You will lead the design and optimization of Manhattan Active WMS solutions for a major DC transformation. Requires 7+ years of Manhattan WMS (WMOS/MAWM) experience, API development, and Google Cloud skills. Enjoy flexible schedul...
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United States , Atlanta
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Not provided
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Genuine Parts Company
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Sr. System Engineer
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Seeking a Senior Systems Engineer with an active TS/SCI clearance and polygraph for a full-time role in Fort Meade, MD. This position requires a Bachelor's degree and 15+ years of experience in systems engineering. You will provide technical analysis, configuration management, and support for cri...
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United States , Fort Meade
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Not provided
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2HB
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Sr. Staff System Engineer, Flight-by-Wire
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Join Archer in San Jose to lead advanced Fly-by-Wire flight control systems for our all-electric aircraft. This senior role requires 10+ years of FBW development/certification experience and expertise with DO-178C and international aviation authorities. You will provide technical leadership, mana...
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United States , San Jose
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257500.00 - 270375.00 USD / Year
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Archer Aviation
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Sr Software System Design Engineer
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Seeking a Senior Software System Design Engineer in Bangalore to innovate on HPE's Green Lake cloud platform. Utilize 8-12+ years of expertise in Java/Groovy/C++ and cloud-native design to build distributed, secure hybrid cloud systems. This role demands a strong background in software architectu...
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India , Bangalore
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Not provided
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Hewlett Packard Enterprise
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Sr. Engineer - System Owner (Inspection & Packaging)
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Join Amgen Dun Laoghaire as a Senior Engineer - System Owner for Inspection & Packaging. You will own and be the SME for new syringe inspection equipment in a state-of-the-art aseptic facility. This role requires a degree in engineering and senior-level experience in pharma/medical device inspect...
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Ireland , Dun Laoghaire
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Amgen
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Sr. Project Equipment Engineer / System Owner
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Join Amgen as a Senior Project Equipment Engineer in Dun Laoghaire. Lead technical projects in a state-of-the-art aseptic pharmaceutical facility, from concept to operational readiness. This role requires a degree, 5+ years' biotech experience, and strong project management skills. Enjoy a compet...
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Ireland , Dun Laoghaire
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Not provided
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Amgen
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Sr. System Test Validation Engineer
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Join our Austin-based team as a Senior System Test Validation Engineer. You will develop and execute next-generation system tests for enterprise server firmware (BIOS/IFWI). This role requires strong C/C++/Python skills and expertise in pre/post-silicon validation. You will validate complex featu...
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United States , Austin
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Salary
112800.00 - 169200.00 USD / Year
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AMD
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About the Sr. System Engineer role

A Senior System Engineer is a pivotal role that bridges the gap between high-level architectural design and the hands-on management of complex IT and operational technology infrastructures. Professionals in these jobs are responsible for ensuring that an organization’s core systems—whether they are cloud-based platforms, on-premise networks, or specialized manufacturing equipment—operate reliably, securely, and efficiently. The title often implies a deep technical expertise combined with strategic oversight, making these roles critical to both daily operations and long-term business continuity.

At its core, the profession involves the full lifecycle management of systems. This includes designing and implementing new solutions, conducting rigorous testing, and overseeing the seamless integration of hardware and software. A primary responsibility is maintaining system reliability and performance. Senior System Engineers frequently lead root cause analysis for system failures, using methodologies like FMEA or DMAIC to identify underlying issues and implement corrective and preventive actions. They develop and optimize maintenance strategies, often shifting from reactive repairs to predictive and condition-based monitoring to minimize downtime and extend asset life.

Another common responsibility is acting as the technical authority for specific systems or domains. This means owning the technical roadmap, managing upgrades and end-of-life replacements, and ensuring compliance with industry regulations or internal standards. In many environments, especially those in regulated industries, this includes maintaining a validated state for equipment and ensuring data integrity. Collaboration is key; these engineers work closely with cross-functional teams—including operations, quality assurance, and product development—to translate business needs into technical specifications and to support new product introductions or process improvements.

Typical skills required for Senior System Engineer jobs include a strong foundation in engineering principles, often supported by a bachelor’s or master’s degree in engineering, computer science, or a related field. Proficiency in system architecture, network design, and cloud technologies is common. For roles focused on physical systems, knowledge of automation, control systems, and reliability engineering is essential. Soft skills are equally important; these professionals must excel at communicating complex technical insights to non-technical stakeholders, mentoring junior team members, and managing vendor relationships. The ability to lead projects, prioritize tasks under pressure, and drive continuous improvement is a hallmark of success in this field. Ultimately, Senior System Engineer jobs demand a blend of deep technical knowledge, strategic thinking, and collaborative leadership to keep critical systems running at their best.