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Sr. Engineer United States Jobs

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Sr Engineer I, Process Development (Downstream)
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Join Amgen as a Sr. Engineer I, Process Development (Downstream) in Holly Springs, NC. You will lead technology transfer, process optimization, and validation for our FleX Batch facility. Leverage your expertise in biologics purification and cGMP to drive yield improvement and complex investigati...
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United States of America , Holly Springs
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115494.60 - 156257.40 USD / Year
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Amgen
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Sr Network Engineer
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Seeking a Sr Network Engineer in West Des Moines or Sioux Falls to design and secure complex network infrastructure. Requires 8+ years experience with BGP, OSPF, MPLS, VxLAN, and Cisco routers. Lead projects, troubleshoot L1/L2/L3 topologies, and drive cloud network architecture. Enjoy comprehens...
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United States , West Des Moines; Sioux Falls
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74301.00 - 139314.00 USD / Year
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Sammons Financial Group
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Sr. Solutions Engineer - Public Sector - SLED
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Senior Solutions Engineer sought by Palo Alto Networks (Idira) to drive technical wins for SLED accounts in Chicago. Leverage 5+ years of presales experience in identity security and public sector IT to deliver demos, POCs, and tailored solutions. Must understand government compliance (FIPS, FedR...
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United States , Chicago
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198000.00 - 273000.00 USD / Year
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Palo Alto Networks
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Sr. Technical Support Engineer, Strata, US Government
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Join Palo Alto Networks as a Sr. Technical Support Engineer in Plano, TX, supporting U.S. Government clients. Leverage 5+ years of network security expertise, including TCP/IP, VPNs, and NGFW, to resolve complex issues. You’ll provide tailored solutions for public sector customers, ensuring compl...
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United States , Plano
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108800.00 - 176000.00 USD / Year
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Palo Alto Networks Italia
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Sr. Technical Support Engineer
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Join a leading cybersecurity team as a Sr. Technical Support Engineer in Plano, TX. Leverage 5+ years of network security expertise to resolve complex post-sales challenges using advanced tools like Wireshark and AI-powered diagnostics. Drive customer success through tailored support, root cause ...
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United States , Plano
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103400.00 - 167200.00 USD / Year
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Palo Alto Networks Italia
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Sr ASIC Design Verification Engineer (NetSec)
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Join a top-tier ASIC team in Santa Clara as a Sr Design Verification Engineer, driving next-gen firewall ASICs from concept to mass production. Leverage SystemVerilog and UVM to architect test benches, define coverage, and debug across simulation, emulation, and formal verification. Ideal candida...
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United States , Santa Clara
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Palo Alto Networks
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Sr. Devops Engineer AWS
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Seeking a Sr. DevOps Engineer (AWS) to architect cloud-native solutions and automate CI/CD pipelines. You will advise customers on DevOps strategy, leveraging expertise in Terraform, Kubernetes, and Python. This role requires 8+ years as a technical specialist and deep experience with Infrastruct...
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United States
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145000.00 - 165000.00 USD / Year
Megazone Cloud US
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Sr. Software Dev Engineer, Kiro Control Plane
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Amazon seeks a Sr. Software Dev Engineer for the Kiro Control Plane in Bellevue, WA. You will build the Kiro Autonomous Agent, a frontier system for independent development tasks. Requires 5+ years in software development, system design, and cloud services (AWS, Kubernetes). Benefits include heal...
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United States , Bellevue
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168100.00 - 227400.00 USD / Year
Amazon
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Sr. Software Engineer
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Sr. Software Engineer role in Jacksonville, FL, focused on designing scalable serverless cloud solutions. Requires 10+ years of experience with C#/.NET, React.js, and cloud architecture. Lead technical direction, build CI/CD pipelines, and drive engineering standards. Benefits include medical, de...
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United States , Jacksonville
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Robert Half
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Sr. Engineer Software
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Join T-Mobile as a Senior Software Engineer to lead scalable microservices development for the next-gen Order Management Platform. Leverage Java, Spring Boot, and REST APIs while managing cloud-native deployments on Azure/AWS in Frisco, TX. Drive API-first design, event-driven systems, and high-a...
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United States , Frisco
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113600.00 - 205000.00 USD / Year
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T-Mobile
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Sr. DevOps Engineer
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Senior DevOps Engineer needed in San Francisco to scale and optimize a cloud-based SaaS platform. This hybrid role requires 5+ years of experience with AWS, Terraform, CI/CD pipelines, and Python. You will enhance infrastructure performance, automate deployments, and support PostgreSQL databases....
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United States , San Francisco
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Robert Half
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Sr. Network Engineer
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Seeking a Sr. Network Engineer in Laurel, MD, to perform engineering services for network design, implementation, and sustainment. Requires 12+ years of experience, a Bachelor's degree (or substitution), and an IAT Level III certification (DoD 8570.01-M). Must hold a TS/SCI Poly. Benefits include...
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United States , Laurel
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100000.00 - 200000.00 USD / Year
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Applied Network Solutions
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Sr. Data Engineer
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Seeking a Sr. Data Engineer for a 6+ month contract in Boston. You will build scalable data pipelines, optimize PostgreSQL, and leverage AWS (EKS, Lambda) with Python and FastAPI. Ideal candidates have 6+ years of experience, finance domain knowledge, and exposure to AI/RAG solutions. Earn $50-60...
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United States , Boston
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Solomon Page
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Sr Staff Software Escalation Engineer Software
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Seeking a Sr Staff Software Escalation Engineer to resolve complex technical issues for our Privilege Cloud (pCloud) FedRAMP product in Boston. You will collaborate with Development and Support teams, requiring US Citizenship, a Bachelor's in CS, and scripting skills (Python, Bash, PowerShell). I...
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United States , Boston
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Palo Alto Networks
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Sr Zendesk Systems Engineer
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Senior Zendesk Systems Engineer needed in Orlando to own and optimize enterprise-scale Zendesk platforms. Requires 5+ years of hands-on administration, deep expertise in workflows, automations, and APIs, plus JavaScript and Python skills. Lead integrations, migrations, and analytics while driving...
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United States , Orlando
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80.00 USD / Hour
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Beacon Hill
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Gn&C Sr Engineer
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Join NASA’s Human Lander Systems Program as a GN&C Sr Engineer in Huntsville, AL. You will design, model, and simulate control systems for spacecraft and landers using MATLAB, Simulink, and 6-DoF Monte Carlo techniques. Requires a PhD with 19+ years in aerospace engineering and US citizenship. En...
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United States , Huntsville
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Amentum
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Sr Software Engineer
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Join Microsoft’s CEAI team as a Sr Software Engineer in Redmond, WA. Design and build major components of an AI-first agentic sales platform using C#, TypeScript, or Python. You’ll own features end-to-end, from prototype to production, with hands-on experience in LLM-based systems and agent stack...
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United States , Redmond
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119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Sr Principal Electrical Engineer
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Senior Principal Electrical Engineer sought to lead innovative electrical design for medication delivery monitoring and sensing products in Round Lake, US. Requires a Bachelor’s in Electrical Engineering and 10+ years of experience in electromechanical hardware development, ideally in medical dev...
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United States , Round Lake
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128000.00 - 176000.00 USD / Year
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Baxter
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Sr. Lead Machine Learning Engineer
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Capital One seeks a Sr. Lead Machine Learning Engineer to design and productionize ML applications at scale. You will lead Agile teams, build data-intensive solutions with Python or Java, and optimize ML systems using cloud-based architectures. This role requires 8+ years of distributed computing...
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United States , New York; San Francisco; San Jose; Cambridge; McLean
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229900.00 - 286200.00 USD / Year
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Capital One
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Sr Engineer, Enterprise AI
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T-Mobile seeks a Sr Engineer, Enterprise AI to design and scale AI-powered applications using LLMs, RAG, and agentic frameworks. Based in Bellevue or Frisco, this role requires 4-7 years of software engineering experience and expertise in building production-grade AI solutions. You will integrate...
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United States , Bellevue; Frisco
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133100.00 - 240100.00 USD / Year
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T-Mobile
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About the Sr. Engineer role

A Senior Engineer is a highly experienced technical professional who applies advanced engineering principles to design, develop, optimize, and maintain complex systems, products, or processes. Unlike entry-level roles, a Sr. Engineer is expected to operate with significant autonomy, taking ownership of technical deliverables, leading cross-functional projects, and mentoring junior team members. These roles are critical across industries such as biotechnology, pharmaceuticals, software, manufacturing, and energy, where reliability, efficiency, and innovation are paramount.

The core responsibilities of a Sr. Engineer vary by discipline but commonly include system ownership, lifecycle management, and performance optimization. In hardware and manufacturing contexts, this involves ensuring the reliability of critical equipment through preventive and predictive maintenance strategies, root cause analysis of failures, and implementation of corrective actions. A Sr. Engineer often defines maintenance strategies, manages spare parts inventory, and leads equipment improvement projects to enhance uptime and compliance with regulatory standards. In software and systems engineering, the role focuses on architecting scalable solutions, developing full software stacks, and integrating technologies like microservices, virtualization, and big data platforms. Regardless of the field, a Sr. Engineer is a key driver of structured problem-solving, using methodologies such as Failure Modes and Effects Analysis (FMEA), Design of Experiments (DOE), and root cause analysis to identify and mitigate risks.

Typical skills and requirements for Sr. Engineer jobs include a bachelor’s degree in engineering or a related field, with many positions requiring a master’s or doctorate. Experience levels generally range from 4 to 10 years of relevant work, depending on educational background. Technical expertise is essential, whether in mechanical design, software architecture, or bioprocess equipment. Beyond technical depth, a Sr. Engineer must demonstrate proficiency in data analysis, technical writing, and cross-functional collaboration. Strong communication skills are vital for translating complex technical findings into actionable insights for operations, quality, and management teams. Leadership ability is also a common requirement, as these professionals often supervise base-level engineers, mentor colleagues, and lead multi-functional teams to resolve system-level challenges.

In summary, Sr. Engineer jobs represent a career stage where professionals shift from executing tasks to owning outcomes. They are trusted to make high-impact decisions that affect product quality, system reliability, and operational efficiency. Whether optimizing a pharmaceutical manufacturing line, designing a robust drug delivery device, or building a resilient software platform, the Sr. Engineer is the technical backbone that ensures projects are delivered with excellence. This role offers a blend of hands-on technical work, strategic thinking, and mentorship, making it a pivotal position for driving innovation and maintaining competitive advantage in any engineering-driven organization.