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Sr Principal Engineer United States Jobs

24 Job Offers

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Sr Principal Engineer - HSE Global Facilities Delivery
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Lilly
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Sr Principal Engineer, Process (hybrid)
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abbvie
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Sr Principal Engineer, Process
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Lead process engineering workstreams at AbbVie in Durham. Requires an engineering degree, 8+ years in pharmaceutical formulation, and strong project leadership. Drive process validation, optimization, and technical standards.
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abbvie
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Sr Principal Engineer, Process
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Lead process engineering workstreams at AbbVie in North Chicago. Requires an engineering degree, 8+ years in pharmaceutical formulation, and strong project management skills to drive process improvements and validation.
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abbvie
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Sr Principal Software Development Engineer
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Lead software architecture and technical strategy for advanced semiconductor test platforms at FormFactor in Beaverton. Requires C#/.NET expertise, large-scale systems design, and cross-team technical leadership.
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115800.00 - 151935.00 USD / Year
Formfactor
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Sr Principal Engineer - Test Development and Automation
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Lead ATE test automation for cutting-edge semiconductor devices in Automotive and Industrial markets. Requires 20+ yrs experience, C++/C#/Python/Java skills, and hands-on agentic AI expertise. Based in Richardson, USA.
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Globalfoundries
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Sr Principal Electrical Engineer
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Renesas Electronics
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Software Engineer Principal (Sr DevOps Engineer)
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United States, Dallas, Pittsburgh
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PNC Financial Services
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Sr. Principal Engineer/ Principal Engineer – Cloud Platform (10395, 10448)
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Extreme Networks
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Sr. Principal Electrical Engineer
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Twelve
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Software Engineer Principal Sr - Intelligent Automations
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PNC Financial Services
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Sr. Principal Systems Engineer
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United States, Skaneateles Falls
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128000.00 - 176000.00 USD / Year
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Baxter
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Sr Principal Engineer, Automation Projects
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128000.00 - 176000.00 USD / Year
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Baxter
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Sr. Principal Systems Engineer
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128000.00 - 176000.00 USD / Year
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Baxter
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Sr. Principal Process Engineer
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128000.00 - 176000.00 USD / Year
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Baxter
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Sr. Principal Engineer Software (Unit 42)
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Join Palo Alto Networks as a Sr. Principal Engineer in Connecticut, building AI-driven tools for Unit 42’s threat research team. Leverage Python, SQL, and containerization (Docker, Kubernetes) to design intelligent data architectures and automate workflows. Ideal for experts in modern AI, REST AP...
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United States, Connecticut
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126000.00 - 204500.00 USD / Year
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Palo Alto Networks
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Sr. Principal Systems Engineer
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Sr. Principal Systems Engineer sought in Milwaukee to lead technical roadmaps for life-saving medical devices. Leverage 8+ years of engineering experience and expertise in ISO 14971 & IEC 60601 within an Agile SAFe framework. Drive innovation by translating market needs into system requirements, ...
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128000.00 - 176000.00 USD / Year
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Baxter
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Sr Principal Engineer, Automation Projects
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Lead complex automation projects as a Sr Principal Engineer in Round Lake, IL. Requires a BS in Mechanical Engineering, 8+ years of experience, and proficiency in SolidWorks. Drive cross-functional teams to design automated manufacturing equipment, manage budgets, and ensure cGMP compliance. Enjo...
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128000.00 - 176000.00 USD / Year
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Baxter
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Sr. Principal Systems Engineer
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Seeking a Sr. Principal Systems Engineer in Skaneateles Falls, NY. Lead complex, cross-functional programs and drive technical strategy for medical devices. Requires a Bachelor's in Engineering, 8+ years of experience, and deep knowledge of ISO 14971 and IEC 62304. Benefits include medical/dental...
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United States, Skaneateles Falls
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128000.00 - 176000.00 USD / Year
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Baxter
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Sr. Principal Systems Engineer
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128000.00 - 176000.00 USD / Year
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Baxter
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About the Sr Principal Engineer role

Sr. Principal Engineer jobs represent the pinnacle of individual technical contribution and leadership within the engineering domain. Professionals in these roles are not just senior engineers; they are recognized as industry experts, technical visionaries, and pivotal leaders who shape the technological future of their organizations. They operate at the intersection of deep technical mastery, strategic business acumen, and influential mentorship, driving innovation and solving the most complex, high-impact challenges.

Typically, a Sr. Principal Engineer is responsible for setting the long-term technical vision and architectural direction for critical systems and platforms. They lead the design and implementation of highly scalable, reliable, and performant solutions, often making foundational decisions that affect the entire product ecosystem. Their day-to-day activities involve architecting systems from the ground up, conducting deep technical reviews, and establishing engineering best practices and standards that elevate the entire organization's output. A core responsibility is to deconstruct ambiguous, large-scale problems into actionable technical roadmaps, guiding multiple teams towards a coherent and elegant solution.

Beyond hands-on architecture and coding, these roles carry significant leadership duties. Sr. Principal Engineers are expected to be force multipliers, actively mentoring senior engineers, principal engineers, and technical managers. They foster a culture of excellence, continuous learning, and rigorous engineering discipline. Their influence extends across departments; they frequently collaborate with executive leadership, product management, and other business units to align technical strategy with business goals, translating market needs into technical requirements. They are the go-to authorities for critical technical decisions, risk assessment, and troubleshooting systemic issues.

The typical skill set for these elite positions is extensive. It requires profound, hands-on expertise in software development, system design, and distributed architectures, often with deep specialization in areas like cloud-native development, scalability patterns, or specific technology stacks. Strong proficiency in modern programming languages, databases, and DevOps practices is a given. However, the differentiating factors are strategic thinking, exceptional communication, and leadership. They must articulate complex technical concepts to diverse audiences, advocate for technical investment, and navigate organizational dynamics to drive consensus. A proven track record of leading large-scale, multi-team projects from conception to delivery is essential, alongside a mindset of innovation and a relentless focus on quality and long-term maintainability.

For organizations, hiring for Sr. Principal Engineer jobs is an investment in technical excellence and future-proofing their core technology. For professionals, it is a career stage defined by unparalleled impact, where their technical depth directly shapes the company's trajectory and defines industry standards.