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Sr Machine Learning Engineer United States Jobs

14 Job Offers

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Sr Staff Machine Learning Engineer (ADEM)
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Sr Staff Machine Learning Engineer (ADEM) at Palo Alto Networks in Santa Clara, CA. Architect the future of endpoint security across Windows, macOS, and Linux. Requires 6+ years of experience, expertise in Rust or Go, and deep OS internals knowledge. Leverage AI-powered development tools to solve...
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United States , Santa Clara
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Salary
147000.00 - 237500.00 USD / Year
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Palo Alto Networks
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Sr Engineer, Machine Learning Engineering
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Senior Machine Learning Engineer sought to design, deploy, and scale LLMs and generative AI solutions in production. You will build end-to-end ML pipelines, implement MLOps on AWS/GCP/Azure, and develop RAG systems. Requires 5+ years in ML engineering and 1+ year with LLMs. Based in Bellevue, Atl...
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United States , Bellevue; Atlanta; Overland Park; Herndon
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127000.00 - 229100.00 USD / Year
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T-Mobile
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Sr. Lead Machine Learning Engineer
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Capital One seeks a Sr. Lead Machine Learning Engineer to design and productionize ML applications at scale in McLean, VA or New York, NY. You will lead Agile teams, optimize ML systems using Python or Java, and leverage cloud-based architectures. Requires 8+ years in distributed computing and 3+...
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United States , McLean, Virginia; New York, New York
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229900.00 - 286200.00 USD / Year
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Capital One
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Sr. Principal Machine Learning Engineer
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Universal Ads seeks a Sr. Principal Machine Learning Engineer to architect and scale the ML stack powering real-time ad delivery across CTV. This strategic leadership role involves setting the long-term vision for model architecture, distributed systems, and bidding algorithms. You will collabora...
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United States
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192396.16 - 450928.49 USD / Year
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Comcast Advertising
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Sr Machine Learning Engineer, Pricing
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Lead ML innovation at Uber as a Sr. Machine Learning Engineer on the Dynamic Supply Pricing team. Develop real-time pricing models and large-scale distributed systems for billions of rides in New York, Seattle, San Francisco, or Sunnyvale. Requires 4+ years deploying ML solutions in production wi...
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United States , New York; Seattle; San Francisco; Sunnyvale
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202000.00 - 224000.00 USD / Year
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Uber
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Sr Staff Machine Learning Engineer (Web Security)
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Join our Web Security Research team in Santa Clara as a Senior Staff Machine Learning Engineer. You will build AI-powered detection models to combat phishing and malicious URLs, using TensorFlow/PyTorch. Leverage your strong Python skills and security expertise to create global threat prevention ...
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United States , Santa Clara
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141000.00 - 228075.00 USD / Year
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Palo Alto Networks
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Sr SOC Verification Engineer, Cloud-Scale Machine Learning Acceleration
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Join Amazon's Machine Learning Acceleration team to verify next-generation AI SOCs like Inferentia and Trainium. As a Senior SOC Verification Engineer, you'll develop testbenches with SystemVerilog/UVM and ensure silicon quality. This role is based in Cupertino or Austin and offers comprehensive ...
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United States , Cupertino; Austin
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159200.00 - 247600.00 USD / Year
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Amazon Pforzheim GmbH
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Sr Staff Machine Learning Engineer - Ads
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Lead the evolution of Uber's Ads platform as a Senior Staff Machine Learning Engineer. You will design advanced ML systems, own the end-to-end model lifecycle, and build scalable architecture in San Francisco or Sunnyvale. This role offers technical leadership, high impact on ads delivery, and co...
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United States , San Francisco; Sunnyvale
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267000.00 - 297000.00 USD / Year
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Uber
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Sr. Machine Learning Engineer – Context Engineering
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United States , New York City; Palo Alto; Chevy Chase
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115000.00 - 230000.00 USD / Year
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Geico
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Sr Software Engineer - Machine Learning
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Join Uber's mission to redefine global mobility and logistics. As a Senior Machine Learning Engineer, you'll design, build, and deploy scalable ML models that impact millions. This role requires expertise in Python/Java/C++ and 3+ years of productionizing ML solutions at scale. Collaborate with c...
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United States , New York; Seattle; San Francisco; Sunnyvale
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202000.00 - 224000.00 USD / Year
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Uber
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Sr. Machine Learning Engineer
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Join Highspot's Machine Learning Team in Seattle to develop next-gen AI for a leading sales enablement platform. As a Senior ML Engineer, you'll build and deploy scalable models using Python and frameworks like TensorFlow/PyTorch. This role offers comprehensive benefits, flexible PTO, and a focus...
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United States , Seattle
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171000.00 - 254100.00 USD / Year
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Highspot
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Sr. Computer Vision and Machine Learning Engineer
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Seeking a Senior Computer Vision and Machine Learning Engineer in Bridgewater, USA. Develop production AI solutions using PyTorch/TensorFlow for real-time object detection and segmentation. Requires 5+ years of Python, full-stack API development, and AWS deployment experience. Ideal for a proacti...
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United States , Bridgewater
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75000.00 - 90000.00 USD / Year
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Invonto
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Sr. Machine Learning Engineer
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Join our StudioLAB innovation team as a Senior Machine Learning Engineer for a 12-month project in Burbank. Apply cutting-edge ML and Python to solve creative challenges in cinematic pipelines and theatrical experiences. This role requires 5+ years of ML experience, proficiency in PyTorch/TensorF...
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United States , Burbank
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Not provided
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Software Resources
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Sr Machine Learning Engineer -AI/ML- US Remote
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Lead the development of a secure, enterprise-scale AI/ML platform at Amgen in this senior remote role. Design core infrastructure and governance for deploying classical ML, deep learning, and LLMs. Leverage expertise in Python, cloud, MLOps, and GenAI tooling to enable hundreds of practitioners.
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United States , Jacksonville
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Salary
164029.00 - 209103.00 USD / Year
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Amgen
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About the Sr Machine Learning Engineer role

A Senior Machine Learning Engineer is a specialized role that sits at the intersection of data science, software engineering, and systems architecture. Professionals in this position are responsible for designing, building, and deploying machine learning models and systems that operate reliably at scale. Unlike data scientists who focus on exploratory analysis and model prototyping, Senior Machine Learning Engineers focus on the production lifecycle—taking models from concept to deployment, monitoring their performance in real-time, and ensuring they integrate seamlessly into larger software ecosystems.

The primary responsibilities of a Senior Machine Learning Engineer include architecting and implementing end-to-end ML pipelines, from data ingestion and feature engineering to model training, validation, and serving. They work closely with data scientists to understand modeling objectives and then build robust infrastructure that supports high-throughput, low-latency predictions. This often involves leveraging cloud-based platforms, distributed computing frameworks, and containerization technologies. A significant portion of the role is dedicated to MLOps—automating model retraining, managing version control for models and data, setting up continuous integration and deployment pipelines, and establishing monitoring systems to detect model drift and degradation.

Technical expertise is critical for these roles. Senior Machine Learning Engineers typically possess deep proficiency in programming languages such as Python, Java, or Scala. They are experienced with big data tools like Apache Spark, real-time stream processing frameworks such as Apache Flink or Kafka, and modern ML libraries including TensorFlow, PyTorch, or scikit-learn. A strong understanding of machine learning algorithms—including deep neural networks, ensemble methods, and optimization techniques—is essential, as is knowledge of software engineering best practices like test automation, code review, and system design. Many positions also require familiarity with mathematical optimization, algorithmic game theory, or reinforcement learning, depending on the application domain.

Beyond technical skills, these engineers must be effective collaborators. They regularly partner with product managers, data scientists, and software engineers to define technical roadmaps, prioritize features, and align model performance with business objectives. Senior professionals often mentor junior team members, lead technical discussions, and contribute to architectural decisions that shape the long-term evolution of the ML platform. Strong communication skills are necessary to explain complex technical concepts to non-technical stakeholders and to advocate for best practices in responsible and explainable AI.

The demand for Senior Machine Learning Engineer jobs continues to grow across industries such as technology, finance, advertising, e-commerce, and transportation. Companies seek individuals who can not only build sophisticated models but also ensure they are scalable, maintainable, and aligned with regulatory and ethical standards. For professionals seeking a challenging career at the forefront of applied artificial intelligence, Senior Machine Learning Engineer jobs offer the opportunity to work on cutting-edge problems, drive tangible business impact, and shape the future of intelligent systems.