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Senior Systems Software Engineer United States Jobs

31 Job Offers

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Senior Software Engineer - System Optimization
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Join Microsoft’s AI Frameworks team in Mountain View as a Senior Software Engineer specializing in System Optimization. You’ll optimize inference performance for OpenAI and LLM models, using C++, Python, and co-designing HW/SW interfaces at cloud scale. Requires a BS in CS, 4+ years of coding exp...
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United States , Mountain View
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119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Senior Software Engineer, Embedded Systems
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Join GM's Vehicle Mechatronics Embedded Controls team as a Senior Software Engineer. Develop embedded C software for the Body domain, focusing on vehicle motion, comfort, and access systems. This role requires 6+ years of experience and offers incentive-based pay in Mountain View. Collaborate in ...
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United States , Mountain View
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158000.00 - 241900.00 USD / Year
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General Motors
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Senior Systems Software Engineer
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Lead the development of Linux system management and monitoring infrastructure at HPE. This hybrid role in San Juan requires expert Golang skills to build Debian-based tools for software lifecycle and observability. We seek a senior engineer with 7-10+ years' experience in systems programming and ...
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United States , San Juan
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Not provided
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Hewlett Packard Enterprise
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Senior Software Engineering Manager - Pharmacy Systems
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Lead backend development for CVS Health's innovative pharmacy systems in Woonsocket. This senior manager role requires 7+ years in software engineering, including 5+ with Java/Spring Boot and 3+ in leadership. You'll build scalable GraphQL APIs, mentor engineers, and shape digital healthcare. Enj...
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United States , Woonsocket
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130295.00 - 260590.00 USD / Year
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CVS Health
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Senior Software System Design Engineer
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Join our team in Florida as a Senior Software System Design Engineer. You will architect and own scalable CI/CD and automation platforms for complex software stacks. We seek an expert in distributed systems, containerization (Docker), and workflow orchestration (e.g., Jenkins) with strong Python/...
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United States , Florida
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134400.00 - 201600.00 USD / Year
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AMD
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Senior Systems Software Engineer
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United States , New York
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Continua
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Senior Systems Software Engineer
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United States , San Francisco
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172000.00 - 209000.00 USD / Year
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Crusoe
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Senior Software Engineer, Backend Systems
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United States
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184600.00 - 260700.00 USD / Year
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Docker
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Senior Software Engineer (Agentic Systems)
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Join Tavus as a Senior Software Engineer specializing in Agentic Systems. You will be the technical driver for our Conversational Video Interface, building complex, production-grade LLM-based agents. This hands-on role in San Francisco requires deep Python expertise and experience with open-sourc...
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United States , San Francisco
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160000.00 - 250000.00 USD / Year
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Tavus
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Senior Software Engineer - Autonomous Software Systems
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Join our Autonomous Vehicle Health team as a Senior Software Engineer. Develop critical C++ frameworks and tools to monitor and ensure the runtime health of self-driving systems in Austin or California. This role requires expertise in Linux, C++17+, and Python to deploy and monitor software acros...
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United States , Austin, Texas; Mountain View, California; Sunnyvale, California
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175000.00 - 230000.00 USD / Year
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General Motors
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Senior Software Engineer - Autonomous Systems
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United States , Seattle
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145000.00 - 200000.00 USD / Year
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Palantir Technologies
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Senior Software Engineer, Marketing Systems
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Seize this opportunity to shape the future of healthcare marketing technology. As a Senior Software Engineer for Marketing Systems, you will architect solutions on Salesforce Marketing Cloud (SFMC) and CMS platforms like Webflow. Your expertise in AMPscript, SQL, and data integrations will drive ...
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United States , Manchester, NH / Marlborough, MA
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150000.00 - 165000.00 USD / Year
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Sequel Med Tech
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Senior Software Engineer (Agentic Systems)
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United States , San Francisco
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160000.00 - 250000.00 USD / Year
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Helpcare AI
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Senior Systems Software Engineer
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Join Exact Sciences in Madison as a Senior Systems Software Engineer. Architect and develop embedded software for robotics and medical instrumentation to scale life-saving cancer tests. This role requires 6+ years' experience, a software engineering degree, and expertise in the full development l...
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United States , Madison
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101000.00 - 172000.00 USD / Year
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Exact Sciences
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Senior Software Engineer - Build Systems
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Join Microsoft as a Senior Software Engineer specializing in Build Systems. Modernize compilers and developer tooling for large-scale, cloud-first applications in Redmond. Leverage AI-powered tools to solve complex engineering challenges and improve developer efficiency. Requires expertise in C/C...
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United States , Redmond
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119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Senior Security Software and System Engineer
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Join HPE's Cybersecurity Lab as a Senior Security Software and System Engineer in Aguadilla. You will design and implement security solutions, conduct penetration testing, and develop automation tools to enhance product and supply chain security. This role requires extensive experience in softwar...
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United States , Aguadilla
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Not provided
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Hewlett Packard Enterprise
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Senior Security Software And System Engineer
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Join HPE's Cybersecurity Lab as a Senior Security Software and System Engineer in Aguadilla. Design and implement advanced security solutions, focusing on penetration testing, cryptographic validation, and automation tools. Leverage your expertise in secure software architecture, network security...
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United States , Aguadilla
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Not provided
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Hewlett Packard Enterprise
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Senior Systems Software Engineer
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Join our team in Palo Alto as a Senior Systems Software Engineer for Vision. You will design and optimize low-latency, high-throughput vision subsystems for humanoid robots. This role requires deep C++/Linux expertise and experience with real-time systems, hardware accelerators, and performance o...
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United States , Palo Alto
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137861.00 - 240000.00 USD / Year
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1X Technologies
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Senior Software Engineer - ERP Systems
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Lead the internal software stack powering sales, manufacturing, and supply chain. Architect full-stack systems on Odoo/NetSuite with Python, React, and PostgreSQL. Design APIs, integrate with PLM/MES, and own projects from design to deployment. This Palo Alto role offers competitive benefits for ...
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United States , Palo Alto
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150000.00 - 221000.00 USD / Year
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1X Technologies
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Senior Software Engineer – GTM Systems
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Join Intercom as a Senior Software Engineer for GTM Systems in Chicago. Design and build scalable internal systems using Python, SQL, and Salesforce. Leverage data tools like Snowflake and DBT, and work on AI-driven tooling. Enjoy competitive compensation, comprehensive benefits, and a collaborat...
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United States , Chicago
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185000.00 - 220000.00 USD / Year
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Intercom
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About the Senior Systems Software Engineer role

Discover and apply for Senior Systems/Software Engineer jobs, a pivotal career path at the intersection of deep technical architecture and hands-on software development. Professionals in this senior role are the cornerstone of complex technical projects, responsible for designing, building, and maintaining the robust systems and software that power modern enterprises. This is not an entry-level coding position; it is a strategic role demanding a holistic understanding of how software interacts with hardware, networks, and operating environments to deliver reliable, scalable, and high-performance solutions.

Typically, a Senior Systems/Software Engineer engages in the full lifecycle of system creation. Common responsibilities include analyzing system requirements, architecting high-level designs, and developing critical software components. They write and review code for everything from low-level operating system modules and compilers to networking protocols, distributed databases, and cloud-native services. A significant part of their role involves troubleshooting, debugging, and performance optimization, often diagnosing intricate issues that span multiple layers of the technology stack. They are also expected to create and execute comprehensive test plans, develop automation tools, and produce detailed technical documentation. Leadership is implicit in the title; these engineers mentor junior team members, collaborate cross-functionally with QA and operations teams, and drive technical decisions to resolve complex challenges.

To excel in Senior Systems/Software Engineer jobs, a specific set of skills and experience is required. A strong foundation in computer science fundamentals—data structures, algorithms, and systems design—is non-negotiable. Proficiency in multiple programming languages (such as C++, Java, Python, or Go) and scripting is essential. Deep knowledge of operating systems (Linux/Unix internals), networking concepts (TCP/IP, L2/L3 protocols), and software engineering best practices (version control, CI/CD) is standard. Experience with distributed systems, cloud platforms (AWS, Azure, GCP), and containerization technologies (Docker, Kubernetes) is increasingly critical. On the soft skills side, excellent problem-solving abilities, effective communication for articulating technical concepts, and project leadership are paramount. Most positions require a bachelor’s or master’s degree in Computer Science, Electrical Engineering, or a related field, coupled with 5+ years of progressive, hands-on experience in systems-level software development.

For seasoned professionals seeking to leverage their extensive technical expertise to build foundational technology, exploring Senior Systems/Software Engineer jobs offers a path to substantial impact, guiding projects from conception through to deployment and evolution in a constantly changing digital landscape.

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