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Senior Systems Engineer United States, San Francisco Jobs

10 Job Offers

Technology Engineer – Senior (1043) - Systems Specialty - Citywide
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Senior Technology Engineer sought for Citywide Systems Specialty in San Francisco. Lead operational support for complex cloud, on-premises, and hybrid systems. Requires an associate degree in computer science or related field plus one year of system/platform experience. Drive infrastructure-as-co...
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United States , San Francisco
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Salary
156000.00 - 196300.00 USD / Year
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City and County of San Francisco
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Until further notice
Senior Systems Engineer, AM&D Services & Products
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Senior Systems Engineer sought for Uber’s Autonomous Mobility & Delivery Safety team in San Francisco, Seattle, or New York. You will define safety frameworks and V&V strategies (ISO 26262, SOTIF) for complex AV integrations. Requires 7+ years in systems engineering with hardware/software focus a...
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United States , New York, New York; Seattle, Washington; San Francisco, California
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Salary
171000.00 - 190000.00 USD / Year
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Uber
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Senior Hardware Systems Engineer
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Senior Hardware Systems Engineer sought by Crusoe, a vertically integrated AI infrastructure company. Drive the full hardware lifecycle for high-performance compute platforms, leveraging 8+ years of experience in PCIe, InfiniBand, and NVMe debugging. Based in San Francisco, this role offers compe...
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United States , San Francisco
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Salary
172000.00 - 209000.00 USD / Year
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Crusoe
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Until further notice
Senior Lead Software Engineer, Distributed Systems (Golang + Python on Kubernetes)
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Senior Lead Software Engineer sought by Capital One to drive AI/ML transformation in San Francisco. You will lead a team building distributed systems using Golang, Python, and Kubernetes on AWS. Requires 6+ years in software engineering and cloud expertise. Join a collaborative team pioneering Ge...
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United States , San Francisco, California
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Salary
229900.00 - 286200.00 USD / Year
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Capital One
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Until further notice
Senior Lead Software Engineer, Distributed Systems (Golang + Python on Kubernetes)
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Senior Lead Software Engineer, Distributed Systems (Golang + Python on Kubernetes) sought by Capital One to drive AI/ML transformation. Lead a team building robust cloud-based solutions on AWS, Azure, or GCP. Requires 6+ years in software engineering with expertise in Golang, Python, and Kubernet...
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Location
United States , San Francisco; McLean; New York; San Jose; Cambridge
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Salary
229900.00 - 286200.00 USD / Year
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Capital One
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Senior Systems Software Engineer
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United States , San Francisco
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Salary
172000.00 - 209000.00 USD / Year
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Crusoe
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Until further notice
Senior Systems Engineer - Infrastructure & Platform Reliability
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Join Lambda to build the world's best AI cloud infrastructure. As a Senior Systems Engineer, you will design and deliver software to improve the reliability and scalability of our internal platforms in San Francisco/San Jose. We seek experts in cloud platforms (AWS, GCP), automation (Terraform, A...
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United States , San Francisco; San Jose
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Salary
206000.00 - 310000.00 USD / Year
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Lambda
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Senior Software Engineer (Agentic Systems)
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Join Tavus as a Senior Software Engineer specializing in Agentic Systems. You will be the technical driver for our Conversational Video Interface, building complex, production-grade LLM-based agents. This hands-on role in San Francisco requires deep Python expertise and experience with open-sourc...
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United States , San Francisco
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Salary
160000.00 - 250000.00 USD / Year
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Tavus
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Senior Software Engineer (Agentic Systems)
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United States , San Francisco
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Salary
160000.00 - 250000.00 USD / Year
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Helpcare AI
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Senior Machine Learning Systems Engineer
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Join Abridge in San Francisco as a Senior Machine Learning Systems Engineer. You will build and optimize core ML infrastructure, focusing on scalable Kubernetes clusters and high-performance model serving. Expertise in production ML, distributed systems, and container orchestration is key. Enjoy ...
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United States , San Francisco
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Salary
221000.00 - 260000.00 USD / Year
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Abridge
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Until further notice

About the Senior Systems Engineer role

Explore Senior Systems Engineer Jobs and discover a pivotal career at the intersection of deep technical expertise and strategic project leadership. Senior Systems Engineers are the architectural backbone of complex technological initiatives, responsible for designing, integrating, and maintaining sophisticated systems that form the core infrastructure of modern organizations. This role transcends singular disciplines, requiring a holistic approach to ensure that all system components—whether hardware, software, or network—work seamlessly together to meet business and performance objectives.

Professionals in these senior roles typically bear the responsibility for the entire systems lifecycle. They analyze requirements, architect robust solutions, and oversee implementation and deployment. A core duty involves troubleshooting high-level issues, performing root cause analysis, and ensuring system reliability, security, and scalability. They act as critical liaisons, translating business needs into technical specifications and guiding cross-functional teams of developers, network administrators, and other engineers. Furthermore, Senior Systems Engineers are often tasked with establishing best practices, creating documentation, mentoring junior staff, and driving continuous improvement through automation and process refinement.

The skill set for these jobs is both broad and deep. A strong foundation in systems theory is essential, coupled with expertise in specific domains such as cloud platforms (AWS, Azure, GCP), virtualization, scripting and automation (Python, Bash, PowerShell), and infrastructure as code (Terraform, Ansible). Proficiency in monitoring and observability tools is crucial for maintaining system health. Beyond technical prowess, successful candidates demonstrate exceptional problem-solving abilities, project management skills, and clear communication to interact effectively with both technical teams and stakeholders. Typically, employers seek candidates with a bachelor’s degree in computer science, engineering, or a related field, supplemented by several years of hands-on systems engineering experience, with a proven track record in designing and managing complex, scalable environments.

Senior Systems Engineer jobs represent a career path for seasoned technical professionals ready to take on architectural ownership and strategic influence. These positions are found across every industry, from finance and healthcare to technology and manufacturing, offering the opportunity to build and sustain the critical systems that power innovation and operational excellence. If you are a systems thinker with a passion for integration, optimization, and leadership, exploring Senior Systems Engineer roles could be your next career milestone.