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Senior System Engineer Jobs

462 Job Offers

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Senior Mechanical Systems Engineer
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Denmark , Kongens Lyngby
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Microsoft Corporation
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Senior Systems Operations Engineer
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India , Bengaluru
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Wells Fargo
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Systems Integration Engineer (Mid-Level or Senior)
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Join Boeing’s 787 Systems Integration Engineering team in North Charleston, SC. As a Mid-Level or Senior Engineer, you will lead cross-functional teams on large-scale multi-system projects from concept to delivery. Requires a Bachelor’s in Engineering or related field and 2+ years of complex syst...
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United States , North Charleston
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112200.00 - 185150.00 USD / Year
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Boeing
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Senior System Performance Engineer
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United States , Austin;Mountain View
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128700.00 - 261300.00 USD / Year
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General Motors
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Senior Aerodynamics Systems Engineer-Motorsports
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United States , Concord
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125200.00 - 192700.00 USD / Year
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General Motors
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Senior Quality Systems Engineer
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United States
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Avanos
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Systems Engineer, Senior
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Senior Systems Engineer needed at Hanscom AFB, MA, supporting AFLCMC/HB. Requires a Bachelor’s degree, 10+ years of experience (5 in DoD), and an active Secret clearance. Key skills include Model Based Systems Engineering, requirements development, and DoD acquisition processes. Enjoy competitive...
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United States , Bedford
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90220.00 - 130000.00 USD / Year
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DCS Corporation
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Systems Engineer, Senior - TS
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Senior Systems Engineer needed to support AFLCMC/C2ISR Division at Robins AFB, GA. Requires Master’s/Doctorate, 12+ years in DoD Test & Cyber Systems Management, and an Active Secret Clearance. You will lead acquisition lifecycle management for C2ISR systems like U-2 and JSTARS. Benefits include ...
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United States , Bedford
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90220.00 - 160000.00 USD / Year
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DCS Corporation
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Senior Distributed Systems Engineer (HPC Platform)
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European Union
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Itransition
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Systems Engineering Senior Analyst - MDM
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India , Noida
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NTT DATA
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Senior Systems Verification Engineer
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Senior Systems Verification Engineer sought by Baxter in Round Lake, IL to drive life-saving medical device testing. Leverage 3+ years of experience in ISO/FDA standards, design controls, and MTBF analysis to develop system verification deliverables. Enjoy comprehensive benefits including medical...
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United States , Round Lake
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96000.00 - 132000.00 USD / Year
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Baxter
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Senior Distributed Storage System Engineer
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United States , San Jose
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136500.00 - 276500.00 USD / Year
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Hewlett Packard Enterprise
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Senior Systems Engineer
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Australia , Canberra
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Randstad
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Senior Systems Verification Engineer
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United States , Round Lake
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96000.00 - 132000.00 USD / Year
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Baxter
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Senior MBSE Systems Engineer
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United States , Huntsville
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Astrion
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Senior Presales Systems Engineer
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United States , Florida
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146000.00 - 343000.00 USD / Year
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Hewlett Packard Enterprise
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Senior Distributed Systems Engineer / Tech Lead
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Senior Distributed Systems Engineer / Tech Lead sought by RTB House to join the Bidding Platform team, processing 20M+ requests per second. You will design high-performance, scalable systems for real-time ad auctions, leveraging Java and Python. Requires deep expertise in distributed systems, con...
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Poland
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RTB House
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Senior EC&I Engineer – Radiological Systems
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United Kingdom , Bristol
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ASSYSTEM
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Senior Design System Engineer
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Spain , Barcelona
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Bsport
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Senior Manager Manufacturing Systems Engineering
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Senior Manager, Manufacturing Systems Engineering at Amgen in Holly Springs, NC. Lead automation engineering teams, drive innovation, and support 24/7 manufacturing operations. Requires expertise in Emerson DeltaV, Process Control Networks, and GMP compliance. Join a mission-driven biotech leader...
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United States , Holly Springs
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148715.15 - 201202.85 USD / Year
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Amgen
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About the Senior System Engineer role

Discover and apply for Senior System Engineer jobs, a critical and high-impact career path at the intersection of technology, strategy, and complex problem-solving. Senior System Engineers are the master architects and technical leaders responsible for designing, integrating, and maintaining the sophisticated systems that power modern enterprises and critical infrastructure. This role transcends basic IT support, focusing on the holistic lifecycle of large-scale systems, from initial concept and requirements analysis through to deployment, integration, and ongoing optimization.

Professionals in these senior-level jobs act as the crucial bridge between business objectives, user needs, and technical execution. A typical day involves analyzing high-level requirements and translating them into detailed system specifications and architectural blueprints. They guide cross-functional engineering teams, ensuring that various components—hardware, software, network, and cloud services—work seamlessly together as a cohesive system. A core responsibility is leading systems integration efforts, developing comprehensive test plans, and managing the technical integrity of major projects. Furthermore, Senior System Engineers are often tasked with evaluating new technologies, conducting feasibility studies and trade-off analyses, and developing strategic roadmaps to evolve system capabilities while ensuring reliability, security, and scalability.

The skill set required for Senior System Engineer jobs is both broad and deep. A strong foundation in systems engineering principles and methodologies is paramount. Candidates typically possess extensive experience with the full systems development lifecycle (SDLC) and are proficient in creating essential documentation such as System Engineering Plans (SEP) and architecture diagrams. Technical expertise often includes knowledge of cloud platforms, cybersecurity principles, and scripting or programming languages like Python for automation and tooling. Beyond technical acumen, these roles demand exceptional analytical and problem-solving skills to deconstruct complex challenges. Leadership and communication are equally critical, as Senior System Engineers must mentor junior staff, collaborate with stakeholders across departments, and clearly articulate technical concepts to non-technical executives and government overseers.

Typical requirements for these positions include a bachelor’s or master’s degree in systems engineering, computer science, information technology, or a related STEM field. Most roles require a substantial professional background, often 10+ years of progressive experience in systems engineering, with a proven track record of leading projects of significant scope and complexity. While specific security clearances are context-dependent for government roles, a general emphasis on systems that handle sensitive data is common. For those seeking a career where they can shape technological strategy and ensure the robustness of mission-critical operations, exploring Senior System Engineer jobs offers a challenging and rewarding pathway.

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