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Senior System Engineer Jobs (Hybrid work)

23 Job Offers

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Senior Equipment Engineer - Packaging System Owner
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Ireland , Dun Laoghaire
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Amgen
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Senior Design System Engineer
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Spain , Barcelona
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Bsport
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Senior System Software Engineer - WSD
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Ireland , Dublin
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Microsoft Corporation
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Senior Software Engineer - System Optimization
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Join Microsoft’s AI Frameworks team in Mountain View as a Senior Software Engineer specializing in System Optimization. You’ll optimize inference performance for OpenAI and LLM models, using C++, Python, and co-designing HW/SW interfaces at cloud scale. Requires a BS in CS, 4+ years of coding exp...
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United States , Mountain View
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119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Senior System Engineer
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Senior System Engineer needed in Miami to lead large-scale distributed infrastructure projects. You will architect, install, and maintain Windows systems across on-premise and cloud platforms (AWS, GCP, Kubernetes). Requires 5+ years of Windows sysadmin expertise, strong troubleshooting skills, a...
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United States , Miami
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93867.22 - 122027.39 USD / Year
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Baptist Health
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Senior Infrastructure System Engineer
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Join our global team in Giza as a Senior Infrastructure System Engineer. You will manage and optimize core Office IT services, focusing on Active Directory and Entra ID. This role requires deep expertise in identity management, PowerShell, and Azure, acting as a key technical escalation point. Yo...
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Egypt , Giza
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Vodafone
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Senior Infrastructure System Engineer
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Join Vodafone in Giza as a Senior Infrastructure System Engineer. You will automate and deploy critical systems using Ansible, Bash, and Agile methodologies. This role focuses on ensuring high availability and managing Active Directory. Contribute to global connectivity while building your career...
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Egypt , Giza
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Vodafone
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Senior System Product Test Engineer
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Join Microsoft's Silicon Engineering team in Hillsboro as a Senior System Product Test Engineer. You will develop System Level Test (SLT) strategies and platforms for cutting-edge cloud hardware. This role requires expertise in pre-silicon validation, product characterization, and system-level de...
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United States , Hillsboro
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119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Senior System Engineer
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Seeking a Senior System Engineer in Hyderabad with 8+ years of enterprise IT experience. This role focuses on Microsoft technologies, O365/Exchange administration, and Active Directory management. You will provide end-user support and troubleshoot infrastructure in a global alternative investment...
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India , Hyderabad
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Alter Domus
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Senior Quantum Engineer - System Characterization
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Join Microsoft Quantum as a Senior Quantum Engineer in Redmond. Characterize and validate cryogenic control hardware for quantum computing systems. Requires a Physics/Engineering degree and 6+ years in low-noise, cryogenic, or RF measurements. Collaborate with multidisciplinary teams in an AI-fir...
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United States , Redmond
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119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Senior System Engineer I
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Lead the hardware lifecycle for advanced RF counter-drone systems in Kassel. Drive products from concept through scalable production, ensuring manufacturing readiness and regulatory compliance. Ideal candidates have an EE/Systems degree and hands-on RF product experience.
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Germany , Kassel
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Axon
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Senior System Software Engineer - WSD
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Ireland , Dublin
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Microsoft Corporation
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Senior System Engineer II
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Join our Global IT Operations team as a Senior System Engineer II in Hyderabad. Leverage your 6+ years of experience with Microsoft Intune, MECM, and Active Directory to enhance end-user experience. Enjoy a hybrid work model, professional development, and a dynamic, supportive international culture.
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India , Hyderabad
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Alter Domus
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Senior System Engineer
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Join Alter Domus in Luxembourg as a Senior System Engineer (Microsoft 365 Specialist). You will manage and secure our global M365 environment, including Exchange Online, Intune, and Entra ID. Leverage your expertise in hybrid configurations, security protocols, and troubleshooting to enhance prod...
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Luxembourg , Luxembourg
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Alter Domus
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Senior Networking System Engineer
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Join Hewlett Packard Enterprise as a Senior Networking System Engineer in Dubai. This hybrid role requires 12+ years of experience, expert pre-sales support skills, and relevant certifications like ACMX/ACDX. You will design complex edge-to-cloud solutions, drive customer engagements, and mentor ...
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United Arab Emirates , Dubai
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Hewlett Packard Enterprise
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Senior Security Software And System Engineer
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Join HPE's Cybersecurity Lab as a Senior Security Software and System Engineer in Aguadilla. Design and implement advanced security solutions, focusing on penetration testing, cryptographic validation, and automation tools. Leverage your expertise in secure software architecture, network security...
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United States , Aguadilla
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Hewlett Packard Enterprise
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Senior Security Software and System Engineer
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Join HPE's Cybersecurity Lab in Aguadilla, Puerto Rico, as a Senior Security Engineer. You will design and implement security solutions, conduct penetration testing, and develop automation tools. This role requires deep expertise in software architecture, cryptography, and security testing (e.g.,...
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Puerto Rico , Aguadilla
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Hewlett Packard Enterprise
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Senior System Development Engineer
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Join HPE Hybrid Cloud in Bangalore as a Senior System Development Engineer. You will develop system software in C/C++/Golang for the flagship Alletra object storage platform, powering AI use-cases. Tackle complex issues, collaborate cross-functionally, and mentor junior engineers in an inclusive ...
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India , Bangalore
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Hewlett Packard Enterprise
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Senior System Engineer - Aeroderivative Turbine
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Join our team in Florence as a Senior System Engineer for Aeroderivative Turbines. You will define system requirements and lead integration throughout the full product lifecycle. This role requires a Master's in Engineering and strong turbomachinery expertise. Collaborate cross-functionally to de...
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Italy , Firenze
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Greentalent
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Senior System Engineer
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Join Alter Domus in Chicago as a Senior System Engineer, specializing in Microsoft 365. You will manage Exchange, Intune, SharePoint, and Defender to enhance security and productivity. This role requires 6+ years of IT experience, strong communication skills, and expertise in the Microsoft ecosys...
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United States , Chicago
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80000.00 - 115000.00 USD / Year
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Alter Domus
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About the Senior System Engineer role

Discover and apply for Senior System Engineer jobs, a critical and high-impact career path at the intersection of technology, strategy, and complex problem-solving. Senior System Engineers are the master architects and technical leaders responsible for designing, integrating, and maintaining the sophisticated systems that power modern enterprises and critical infrastructure. This role transcends basic IT support, focusing on the holistic lifecycle of large-scale systems, from initial concept and requirements analysis through to deployment, integration, and ongoing optimization.

Professionals in these senior-level jobs act as the crucial bridge between business objectives, user needs, and technical execution. A typical day involves analyzing high-level requirements and translating them into detailed system specifications and architectural blueprints. They guide cross-functional engineering teams, ensuring that various components—hardware, software, network, and cloud services—work seamlessly together as a cohesive system. A core responsibility is leading systems integration efforts, developing comprehensive test plans, and managing the technical integrity of major projects. Furthermore, Senior System Engineers are often tasked with evaluating new technologies, conducting feasibility studies and trade-off analyses, and developing strategic roadmaps to evolve system capabilities while ensuring reliability, security, and scalability.

The skill set required for Senior System Engineer jobs is both broad and deep. A strong foundation in systems engineering principles and methodologies is paramount. Candidates typically possess extensive experience with the full systems development lifecycle (SDLC) and are proficient in creating essential documentation such as System Engineering Plans (SEP) and architecture diagrams. Technical expertise often includes knowledge of cloud platforms, cybersecurity principles, and scripting or programming languages like Python for automation and tooling. Beyond technical acumen, these roles demand exceptional analytical and problem-solving skills to deconstruct complex challenges. Leadership and communication are equally critical, as Senior System Engineers must mentor junior staff, collaborate with stakeholders across departments, and clearly articulate technical concepts to non-technical executives and government overseers.

Typical requirements for these positions include a bachelor’s or master’s degree in systems engineering, computer science, information technology, or a related STEM field. Most roles require a substantial professional background, often 10+ years of progressive experience in systems engineering, with a proven track record of leading projects of significant scope and complexity. While specific security clearances are context-dependent for government roles, a general emphasis on systems that handle sensitive data is common. For those seeking a career where they can shape technological strategy and ensure the robustness of mission-critical operations, exploring Senior System Engineer jobs offers a challenging and rewarding pathway.