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Senior System Engineer United States Jobs (On-site work)

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Senior Windows System Engineer
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Seeking a Senior Windows System Engineer in Washington, DC. Manage VMware, Windows Server, and HP hardware in a hybrid Azure environment. Requires 5+ years' experience, strong automation skills, and U.S. Citizenship. We offer competitive salary, profit sharing, and comprehensive benefits.
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United States , Washington, DC
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Bamboo Solutions Corporation
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Senior Systems Software Engineer
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Join Exact Sciences in Madison as a Senior Systems Software Engineer. Architect and develop embedded software for robotics and medical instrumentation to scale life-saving cancer tests. This role requires 6+ years' experience, a software engineering degree, and expertise in the full development l...
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United States , Madison
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101000.00 - 172000.00 USD / Year
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Exact Sciences
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Senior Information System Security Engineer
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United States , Bedford / Hanscom AFB, Massachusetts
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160000.00 - 175000.00 USD / Year
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Astrion
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Systems Engineer, Senior
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Seeking a Senior Systems Engineer with an active Top Secret clearance to support the Air Force's C3BM Division in Bedford. This role requires 10+ years of experience, including 5 in DoD, with expertise in cloud systems, DevSecOps, and acquisition policy. You will provide critical engineering supp...
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United States , Bedford
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87934.00 - 120000.00 USD / Year
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DCS Corporation
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Senior Sensor Systems & Calibration Engineer
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Join Uber's team in Sunnyvale as a Senior Sensor Systems & Calibration Engineer. You will build and scale calibration infrastructure for advanced multi-sensor perception systems. This role requires expertise in sensor calibration, hardware testing, and scripting for automation. Develop production...
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United States , Sunnyvale
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180000.00 - 200000.00 USD / Year
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Uber
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Senior Data Center Commissioning Engineer – Electrical Systems
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Seeking a Senior Data Center Commissioning Engineer for electrical systems in Abilene. This role requires a BSc/MSc in Electrical Engineering and 7+ years of mission-critical commissioning experience. You will lead testing, troubleshooting, and documentation for high/medium voltage systems in dat...
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United States , Abilene
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Veolia
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Senior Systems Engineer
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Join our team as a Senior Systems Engineer in Jersey City. Design and manage core VMware infrastructure, ensuring stability and security. Leverage your 7+ years of experience with vSphere, Windows Server, and enterprise storage. We offer competitive compensation, comprehensive benefits, and profe...
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United States , Jersey City
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Robert Half
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Senior Security Software and System Engineer
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Join HPE's Cybersecurity Lab as a Senior Security Software and System Engineer in Aguadilla. You will design and implement security solutions, conduct penetration testing, and develop automation tools to enhance product and supply chain security. This role requires extensive experience in softwar...
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United States , Aguadilla
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Hewlett Packard Enterprise
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Senior Security SW and System Engineer
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Join HPE's Cybersecurity Lab as a Senior Security SW and System Engineer in Aguadilla. Design and implement advanced security solutions, focusing on penetration testing, cryptographic validation, and automation. Leverage your 6-10 years of expertise in secure software architecture and a deep know...
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United States , Aguadilla
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Hewlett Packard Enterprise
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Senior Information Systems Security Engineer
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Seeking a Senior ISSE with 20+ years' experience to lead security engineering for complex federal systems in Annapolis Junction. Must hold an active clearance, IASAE III compliance (CISSP/ISSEP), and expertise in the RMF. We offer top-tier medical/dental/vision, a 6% 401k match, and significant s...
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United States , Annapolis Junction
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Columbia Technology Partners
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Senior Systems Engineer
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Seeking a Senior Systems Engineer in Annapolis Junction to lead system design and development for complex programs. This role requires 14+ years of experience, a relevant degree, and an active Security Clearance with Polygraph. You will manage requirements, develop technical documentation, and se...
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United States , Annapolis Junction
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Columbia Technology Partners
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Senior Systems Software Engineer
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Join our team in Palo Alto as a Senior Systems Software Engineer for Vision. You will design and optimize low-latency, high-throughput vision subsystems for humanoid robots. This role requires deep C++/Linux expertise and experience with real-time systems, hardware accelerators, and performance o...
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United States , Palo Alto
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137861.00 - 240000.00 USD / Year
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1X Technologies
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Senior Software Engineer - ERP Systems
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Lead the internal software stack powering sales, manufacturing, and supply chain. Architect full-stack systems on Odoo/NetSuite with Python, React, and PostgreSQL. Design APIs, integrate with PLM/MES, and own projects from design to deployment. This Palo Alto role offers competitive benefits for ...
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United States , Palo Alto
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150000.00 - 221000.00 USD / Year
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1X Technologies
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Senior Audio Systems Engineer
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Lead audio systems development for cutting-edge humanoid robots in Palo Alto. Design and tune microphone/speaker hardware, leveraging signal processing and ML for noise reduction. Own the full audio pipeline from prototype to product, ensuring exceptional performance in diverse environments. Comp...
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United States , Palo Alto
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137861.00 - 240000.00 USD / Year
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1X Technologies
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Senior Firmware Engineer - Embedded Systems
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Join our team as a Senior Firmware Engineer in Lincolnshire, United States. You will design, develop, and debug embedded systems using C/C++ for low-level device drivers. This role requires a Bachelor's degree and 6+ years of hands-on firmware experience. Ideal candidates will have exposure to Li...
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United States , Lincolnshire
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Advanced Technology Search Group
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Senior Systems Engineer
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Join our Chicago team as a Senior Systems Engineer to architect and optimize a cutting-edge, low-latency global trading infrastructure. You will leverage deep Linux, automation (Python/Ansible), and performance tuning expertise to solve complex challenges. This role offers ownership of key projec...
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United States , Chicago
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130000.00 USD / Year
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AKUNA CAPITAL
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Senior Systems Security Engineer
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Seeking a Senior Systems Security Engineer in Washington to perform hands-on security engineering and administration. You will apply DISA STIGs across OS, cloud, and virtual platforms, and utilize tools like Splunk, Tenable, and Crowdstrike. This role requires 5-10 years of experience and offers ...
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United States , Washington
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AnaVation
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Senior Systems Engineer
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Join AnaVation's Cross Domain Engineering Team as a Senior Systems Engineer in Vienna, USA. You will architect and automate secure, scalable systems using AWS, on-prem platforms, and scripting tools like Python. This role requires 7-9 years of systems engineering experience and offers robust bene...
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United States , Vienna
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AnaVation
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Senior Network and Systems Engineer
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Join our San Francisco team as a Senior Network and Systems Engineer. This senior consultant role requires expertise in Windows/Mac systems, VMware, cloud (AWS/Azure), and security-focused networking (Cisco, Palo Alto). You'll support Bay Area clients, focusing on architecture, security, and inde...
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United States , San Francisco
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90000.00 - 140000.00 USD / Year
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Cobaltix
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Senior Robotic Systems Integration Engineer
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Join Formlabs in Boston as a Senior Robotic Systems Integration Engineer. You will integrate firmware and hardware for groundbreaking 3D printers, defining control algorithms and managing system requirements. The role requires 5+ years in complex electro-mechanical systems, motion control, and Py...
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United States , Boston
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Formlabs GmbH
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Discover and apply for Senior System Engineer jobs, a critical and high-impact career path at the intersection of technology, strategy, and complex problem-solving. Senior System Engineers are the master architects and technical leaders responsible for designing, integrating, and maintaining the sophisticated systems that power modern enterprises and critical infrastructure. This role transcends basic IT support, focusing on the holistic lifecycle of large-scale systems, from initial concept and requirements analysis through to deployment, integration, and ongoing optimization. Professionals in these senior-level jobs act as the crucial bridge between business objectives, user needs, and technical execution. A typical day involves analyzing high-level requirements and translating them into detailed system specifications and architectural blueprints. They guide cross-functional engineering teams, ensuring that various components—hardware, software, network, and cloud services—work seamlessly together as a cohesive system. A core responsibility is leading systems integration efforts, developing comprehensive test plans, and managing the technical integrity of major projects. Furthermore, Senior System Engineers are often tasked with evaluating new technologies, conducting feasibility studies and trade-off analyses, and developing strategic roadmaps to evolve system capabilities while ensuring reliability, security, and scalability. The skill set required for Senior System Engineer jobs is both broad and deep. A strong foundation in systems engineering principles and methodologies is paramount. Candidates typically possess extensive experience with the full systems development lifecycle (SDLC) and are proficient in creating essential documentation such as System Engineering Plans (SEP) and architecture diagrams. Technical expertise often includes knowledge of cloud platforms, cybersecurity principles, and scripting or programming languages like Python for automation and tooling. Beyond technical acumen, these roles demand exceptional analytical and problem-solving skills to deconstruct complex challenges. Leadership and communication are equally critical, as Senior System Engineers must mentor junior staff, collaborate with stakeholders across departments, and clearly articulate technical concepts to non-technical executives and government overseers. Typical requirements for these positions include a bachelor’s or master’s degree in systems engineering, computer science, information technology, or a related STEM field. Most roles require a substantial professional background, often 10+ years of progressive experience in systems engineering, with a proven track record of leading projects of significant scope and complexity. While specific security clearances are context-dependent for government roles, a general emphasis on systems that handle sensitive data is common. For those seeking a career where they can shape technological strategy and ensure the robustness of mission-critical operations, exploring Senior System Engineer jobs offers a challenging and rewarding pathway.

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