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Senior Staff Machine Learning Engineer Jobs (Hybrid work)

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Senior Staff Machine Learning Engineer
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Lead the development of a cutting-edge AI platform as a Senior Staff Machine Learning Engineer in San Francisco. Design scalable agentic workflows, LLM pipelines, and secure backend systems using Python and FastAPI. Enjoy competitive pay, comprehensive healthcare, generous leave, and flexible hyb...
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United States , San Francisco
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216500.00 - 324500.00 USD / Year
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GoFundMe
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Until further notice
Senior Staff Machine Learning Engineer - Clinical - AI Teams
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Lead the technical direction of AI systems that enhance clinical decision-making at Doctolib in Paris. This senior role requires 10+ years in ML/AI, deep expertise in clinical NLP or LLMs, and a PhD. You will own the roadmap for safe, production ML deployment in a regulated healthcare environment...
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France , Paris
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Not provided
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Doctolib
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Until further notice
Senior Staff Machine Learning Engineer
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Join Corti's mission to expand global healthcare access using AI. As a Senior Staff ML Engineer in Copenhagen, you'll build production models for audio, text, and structured data. We seek expertise in Python, PyTorch/TensorFlow, NLP, and deploying real-world ML pipelines. Enjoy a hybrid work mode...
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Denmark , København
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Not provided
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Life Science Talent
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Until further notice
Explore the pinnacle of machine learning careers with Senior Staff Machine Learning Engineer jobs. This role represents the highest echelon of technical leadership within the AI and ML domain, blending deep hands-on expertise with strategic vision to guide organizations through the complexities of building and deploying impactful, production-scale machine learning systems. Professionals in these positions are not just individual contributors; they are the architects of an organization's ML future, responsible for setting technical direction, mentoring top talent, and ensuring that ambitious AI initiatives translate into reliable, scalable, and measurable business value. Typically, a Senior Staff Machine Learning Engineer owns the end-to-end lifecycle of advanced ML systems. This encompasses defining multi-year technical strategy, leading the design and implementation of complex modeling approaches—from classical algorithms to cutting-edge deep learning and large language models (LLMs)—and establishing robust MLOps practices for seamless deployment and monitoring. A core responsibility is providing broad technical leadership across multiple teams, driving clarity on high-stakes decisions, and fostering collaboration between research, platform engineering, product, and business stakeholders. They champion system excellence, operational rigor, and responsible AI principles throughout the development process. The common skill set for these elite roles is extensive. It requires a profound mastery of machine learning theory and modern frameworks like PyTorch or TensorFlow, coupled with hands-on experience in distributed systems, large-scale model training, and GPU/TPU optimization. Proficiency in Python and deep knowledge of the entire ML stack—from data pipelines and feature stores to model serving infrastructure and automated retraining—is essential. Equally critical are exceptional leadership and communication abilities. These engineers must articulate complex technical strategies to diverse audiences, mentor senior engineers, and align cross-functional teams toward a common vision. Typical requirements for Senior Staff Machine Learning Engineer jobs often include 10+ years of progressive experience in researching, designing, and operating real-time, large-scale ML systems. A strong academic background in Computer Science, Engineering, or a related quantitative field is common, with advanced degrees frequently preferred. The role demands a proven track record of technical leadership, strategic impact, and a unique blend of coding proficiency, architectural insight, and business acumen. For those seeking to define the frontier of applied AI and lead at the intersection of innovation and execution, Senior Staff Machine Learning Engineer jobs offer a challenging and highly influential career path at the forefront of technology.

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