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Senior Software Engineer, Python Jobs

45 Job Offers

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Senior Software Engineer - Conversational AI (Python)
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Join Team Vector as a Senior Software Engineer in Estonia to build agentic voice AI for banking. Requires production AI systems experience, Python skills, and strong architecture judgment.
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Glia
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Senior Backend Software Engineer (Python / FastAPI)
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Senior Backend Engineer (Python/FastAPI) in San Francisco building real-time sensor data pipelines for defense tech. Requires strong Python, streaming systems, and end-to-end ownership. $140k-$240k base plus pre-IPO equity.
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CHAOS Industries
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Senior Software Test Engineer (Python), Intelligence Systems
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Join Anduril as a Senior Software Test Engineer in Reston, VA. Leverage your Python and test automation expertise to validate advanced networking systems for defense technology. Active secret clearance required.
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Anduril Industries
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Senior Full-Stack Software Engineer (Python, React)
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Senior Full-Stack Engineer role (Python, React) at an AI-first global tech company. Build scalable web apps, lead architecture, and work with LLM APIs. Remote/hybrid flexibility, international projects, and strong benefits.
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Exadel Inc (Website)
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Senior Software Test Engineer (Python, Pyspark, Databricks)
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NIQ seeks a Senior Software Test Engineer in Chennai to build scalable big data automation frameworks using Python, Pyspark, and Databricks on Azure. Requires 6-10 years of experience in cloud testing, SQL, and API automation.
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NielsenIQ
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Senior Software Engineer (Backend, Python)
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United Kingdom, London (GB)
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Octopus Energy
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Senior Software Engineer (Python)
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United Kingdom, London (GB)
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Octopus Energy
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Senior Staff Software Engineer | Security Data Platform | Expert in Python
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Armis
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Senior Full Stack Software Engineer ( Strong backend - Python & Go + frontend)
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QAD, Inc.
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Senior Python Software Engineer
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Romania, Employees can work remotely
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Accesa
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Senior Python Software Engineer / RDM
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Inetum
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Senior Python Software Engineer
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Romania, Romania
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3Pillar Global
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Senior Python Software Engineer
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Czech Republic, Czech Republic
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3Pillar Global
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Senior Python Software Engineer - Data Engineer
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3Pillar Global
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Senior Python Software Engineer - Data Engineer
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3pillarglobal.com Logo
3Pillar Global
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Senior Full-Stack Software Engineer (Python / React)
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Romania, Romania
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3Pillar Global
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Senior Full-Stack Software Engineer (Python / React)
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Moldova, Moldova
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3Pillar Global
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Senior Python Software Engineer - Data Engineer
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Costa Rica, Costa Rica
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3Pillar Global
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Senior Full-Stack Software Engineer (Python / React)
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Czech Republic, Czech Republic
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3Pillar Global
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Senior Software (Python) Engineer | Nomagic [25-32k PLN UoP]
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Bee Talents
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About the Senior Software Engineer, Python role

Senior Software Engineer, Python jobs represent a pivotal role in modern technology organizations, where experienced professionals architect, build, and maintain the critical infrastructure that powers everything from backend services and data pipelines to machine learning platforms and developer tooling. These positions typically require a deep mastery of the Python programming language combined with a strong foundation in software engineering principles, system design, and operational excellence. Professionals in this role are responsible for designing scalable distributed systems, improving build and deployment workflows, and ensuring the reliability, performance, and security of production environments.

They often lead complex, cross-cutting initiatives that span multiple teams, tackling challenges such as monorepo health, dependency management, continuous integration and delivery pipelines, and observability. A key aspect of these jobs is the focus on developer experience—creating tooling, templates, and automation that make it easier for other engineers to write, test, and ship high-quality Python code at scale. Senior Software Engineers also play a crucial role in mentoring junior team members, conducting rigorous design and code reviews, and raising the overall technical bar within their organization.

Typical responsibilities include owning projects end-to-end from problem definition through design, implementation, production rollout, and long-term operation; driving improvements in testing strategies, monitoring standards, and documentation; and collaborating closely with product managers, data scientists, and platform teams to align technical solutions with business goals. The skill set required for these jobs goes beyond Python proficiency; candidates must demonstrate expertise in large-scale backend systems, distributed computing, and operational practices such as incident management and performance optimization. Familiarity with the Python packaging ecosystem, build backends, and modern CI/CD tools is often essential, as is experience with database technologies, both relational and NoSQL.

For roles leaning into AI and machine learning, knowledge of ML workflows, data pipelines, and emerging AI-assisted development tools is increasingly valuable. Strong leadership, communication, and stakeholder management skills are also critical, as Senior Software Engineers frequently act as technical representatives for their products, influence architectural decisions, and partner with vendors or external teams. Ultimately, these jobs demand a blend of technical depth, strategic thinking, and a commitment to engineering excellence, making them ideal for seasoned professionals who want to shape how Python is built and operated across an entire organization.