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Senior Software Engineer, Python Jobs

36 Job Offers

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Senior Software Engineer (Python)
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Senior Software Engineer (Python) sought for our Payments & Treasury Technology team in Hyderabad. You will build and scale a treasury management ecosystem using Python, React, and AWS, integrating Kyriba for global client transactions. Requires 5+ years in financial systems, strong Python/React ...
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India , Hyderabad
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Not provided
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Alter Domus
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Senior Software Engineer Python Full Stack with AI
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Senior Software Engineer (Python Full Stack with AI) sought by Wells Fargo in Bengaluru. Drive enterprise automation, testing, and AI initiatives like RAG and Agentic workflows. Requires 6+ years in Python, Django/Flask, React/Angular, and CI/CD. Lead complex projects, remediate vulnerabilities, ...
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India , Bengaluru
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Wells Fargo
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Senior Software Engineer- Python & Unix
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India , Pune
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Citi
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Senior Lead Software Engineer, Distributed Systems (Golang + Python on Kubernetes)
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United States , San Francisco; McLean; New York; San Jose; Cambridge
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229900.00 - 286200.00 USD / Year
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Capital One
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Senior Software Development Engineer - Python Packaging
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Germany , Munich
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AMD
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Senior Software Engineer, Python Platform
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Senior Software Engineer, Python Platform at Uber in Amsterdam. Lead cross-cutting initiatives to build and operate the infrastructure powering AI/ML, data platforms, and backend services at scale. Requires 7+ years of experience, deep Python expertise, and a track record in distributed systems a...
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Netherlands , Amsterdam
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Uber
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Senior Data Software Engineer (Python & PySpark) - Vice President
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Senior Data Software Engineer (VP) sought in Singapore to lead large-scale data solutions using Python, PySpark, and Apache Spark. Requires 7+ years in data engineering, expertise in cloud platforms (AWS, Azure, GCP), and strong SQL/ETL skills. Drive high-impact projects, design distributed syste...
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Singapore , Singapore
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Citi
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Senior Software Engineer (Python) – Fixed Income
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Canada , Mississauga
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94300.00 - 141500.00 USD / Year
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Citi
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Senior Software Engineer, Python
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Uber seeks a Senior Software Engineer, Python to lead critical initiatives shaping its Python ecosystem in Amsterdam. You will architect scalable solutions for build systems, developer tooling, and production infrastructure, impacting AI/ML and data platforms. Ideal candidates have 7+ years of ex...
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Netherlands , Amsterdam
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Uber
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Senior Software Engineer - Python
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India , Pune
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Rapid7
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Senior Software Engineer (Python)
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Senior Software Engineer (Python) sought to build core back-end systems for cloud-based industrial AI solutions. You will design scalable, multi-tenant SaaS platforms using Python, FastAPI, and PostgreSQL, deploying to Kubernetes on Azure. This remote-first role in Poland offers flexible hours, c...
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Poland
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Edvantis
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Senior Software Engineer (Agentic AI) - Python
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Join Doctolib in Paris as a Senior Software Engineer in Agentic AI. Develop a transformative AI Health Companion using Python, focusing on production-grade agentic systems, safety, and evaluation. You'll need 4+ years of experience, a product mindset, and expertise in SDLC best practices. Enjoy t...
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France , Paris
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Doctolib
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Senior Software Engineer Scientific Engine (Python)
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Join our Paris team as a Senior Software Engineer. You will lead the Python scientific engine, mentor junior developers, and optimize code within a microservices architecture. We seek an expert with strong Python skills, a solid engineering background, and fluency in English/French. Enjoy a colla...
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France , Paris
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Descartes Underwriting
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Senior Software Engineer (Python) – Fixed Income
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Join Citi's Fixed Income Technology team in Mississauga as a Senior Python Engineer. Develop high-performance applications for critical trading and market-making systems. Requires 3-5 years of Python, SQL, and strong problem-solving skills. Contribute to innovative, data-driven solutions in a glo...
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Canada , Mississauga, Ontario
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94300.00 - 141500.00 USD / Year
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Citi
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Senior Software Engineer with Python
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Join a leading global legal tech platform in Madrid as a Senior Software Engineer. Utilize your 6+ years of experience with Python, TypeScript, and modern frameworks to build scalable, high-performance web applications. Enjoy a flexible, remote-friendly culture focused on innovation and well-bein...
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Spain , Madrid
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Babel Profiles
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Senior Software Engineer, Python
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Join our Chat group as a Senior Python Engineer and build next-generation AI recruiting products. You will design, implement, and scale AI agentic systems using Python, Kubernetes, and AWS. We offer a remote-friendly culture in Poland, competitive salary, and the chance to make a real impact in H...
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Poland
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SmartRecruiters
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Senior Software Engineer (Python)
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Join our AI Practice as a Senior Python Engineer in Utrecht. Design and maintain a mission-critical, real-time voice application using FastAPI, async Python, and Azure cloud services. This client-facing role offers remote flexibility, private healthcare, and a pension scheme.
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Netherlands , Utrecht
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Sabio Group
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Senior Python Software Engineer
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Bitola, Burgas, Istanbul, Plovdiv, Skopje, Sofia, Varna
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Scalefocus
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Senior Software Engineer - Integration (Python)
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Join our Integration Engineering team as a Senior Software Engineer. Design and deliver robust Python integration solutions for our core platforms, OpenBAS and OpenCTI. Work remotely from France in an async-first environment, ensuring seamless system interoperability. Enjoy competitive pay, equit...
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France
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Filigran
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Senior Software Engineer - Python & React
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Join 3Pillar in Guatemala as a Senior Software Engineer. Leverage your 5+ years of expertise in Python, React, and enterprise systems to architect transformative solutions. You will drive client success through agile development, mentoring, and building scalable, high-quality software. Enjoy comp...
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Guatemala
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3Pillar Global
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About the Senior Software Engineer, Python role

Senior Software Engineer, Python jobs represent a pivotal role in modern technology organizations, where experienced professionals architect, build, and maintain the critical infrastructure that powers everything from backend services and data pipelines to machine learning platforms and developer tooling. These positions typically require a deep mastery of the Python programming language combined with a strong foundation in software engineering principles, system design, and operational excellence. Professionals in this role are responsible for designing scalable distributed systems, improving build and deployment workflows, and ensuring the reliability, performance, and security of production environments.

They often lead complex, cross-cutting initiatives that span multiple teams, tackling challenges such as monorepo health, dependency management, continuous integration and delivery pipelines, and observability. A key aspect of these jobs is the focus on developer experience—creating tooling, templates, and automation that make it easier for other engineers to write, test, and ship high-quality Python code at scale. Senior Software Engineers also play a crucial role in mentoring junior team members, conducting rigorous design and code reviews, and raising the overall technical bar within their organization.

Typical responsibilities include owning projects end-to-end from problem definition through design, implementation, production rollout, and long-term operation; driving improvements in testing strategies, monitoring standards, and documentation; and collaborating closely with product managers, data scientists, and platform teams to align technical solutions with business goals. The skill set required for these jobs goes beyond Python proficiency; candidates must demonstrate expertise in large-scale backend systems, distributed computing, and operational practices such as incident management and performance optimization. Familiarity with the Python packaging ecosystem, build backends, and modern CI/CD tools is often essential, as is experience with database technologies, both relational and NoSQL.

For roles leaning into AI and machine learning, knowledge of ML workflows, data pipelines, and emerging AI-assisted development tools is increasingly valuable. Strong leadership, communication, and stakeholder management skills are also critical, as Senior Software Engineers frequently act as technical representatives for their products, influence architectural decisions, and partner with vendors or external teams. Ultimately, these jobs demand a blend of technical depth, strategic thinking, and a commitment to engineering excellence, making them ideal for seasoned professionals who want to shape how Python is built and operated across an entire organization.