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Senior Scientist United States Jobs

327 Job Offers

Senior Data Scientist, AI & Model Risk
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Senior Data Scientist, AI & Model Risk – Lead end-to-end AI risk assessments for generative AI and LLMs at Cash App. Leverage Python and deep knowledge of transformer models, RAG, and agentic AI to evaluate system design and output integrity. Based in the Bay Area with remote flexibility, this ro...
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United States , Bay Area
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139000.00 - 225000.00 USD / Year
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Cash App
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Senior Survey Scientist
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Senior Survey Scientist sought to drive strategic insights for Marketing, Ops, and Product teams. Leverage expertise in research design, psychometrics, and quantitative methods like regression and conjoint analysis. Requires 5–7+ years of survey research, SQL/Python coding, and Qualtrics proficie...
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United States , New York; San Francisco; Washington
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171000.00 - 190000.00 USD / Year
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Uber
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Senior Data Scientist - Agentic Systems
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Senior Data Scientist - Agentic Systems at Microsoft in Redmond, WA. Design and ship generative AI and LLM-powered agents to automate analytics workflows, including co-PM and project planning tools. Requires a PhD/Master's in Data Science or related field with 3+ years experience. Drive AI-native...
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United States , Redmond
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119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Senior Scientist – Dough
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Senior Scientist – Dough role at Pizza Hut seeks a food R&D expert to lead dough innovation and product development in a global QSR environment. You will drive formulation, optimization, and commercialization of fresh and frozen doughs, collaborating with cross-functional teams. Requires a Food S...
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United States
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99200.00 - 116700.00 USD / Year
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Yum!
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Senior Lead AI Research Scientist – Foundation Models & Agentic AI
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Wells Fargo seeks a Senior Lead AI Research Scientist to drive Foundation Models & Agentic AI innovation in Charlotte, NC. This role leads end-to-end research and deployment of Generative AI systems for real-world financial applications. Candidates need 7+ years in quantitative analytics and a Ma...
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United States , Charlotte
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185000.00 - 300000.00 USD / Year
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Wells Fargo
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Applied Scientist II and Senior
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Join Microsoft as an Applied Scientist II or Senior in Cambridge, MA, and drive AI innovation on Azure. You'll research and implement cutting-edge solutions using LLMs, deep learning, and statistical modeling. Ideal candidates hold a PhD or Master’s in CS or related field with 2+ years of experie...
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United States , Cambridge
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102100.00 USD / Year
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Microsoft Corporation
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Senior Materials Scientist
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Senior Materials Scientist sought to lead groundbreaking R&D in 3D printing materials, from lab discovery to commercialization. Collaborate with engineers to optimize polymer performance for SLA/DLP and SLS printers. Requires a B.S./M.S./PhD in materials science, strong problem-solving skills, an...
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United States , Somerville
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Salary
115000.00 - 142000.00 USD / Year
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Formlabs GmbH
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Senior Data Scientist
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Join Bing as a Senior Data Scientist in Redmond, WA, and drive data-driven decisions for over a billion monthly users. You will develop predictive models, analyze large-scale telemetry, and define key success metrics for search and AI experiences. Requires a PhD/Master’s in Data Science, Statisti...
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United States , Redmond
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Salary
119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Senior SLS Materials Scientist
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Senior SLS Materials Scientist sought to lead groundbreaking polymer R&D for 3D printing in Boston. Drive new materials from lab to market, optimizing thermal dynamics and print parameters. Requires deep materials science expertise, hands-on thermoplastic engineering, and a data-driven experiment...
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United States , Boston
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Salary
115000.00 - 142000.00 USD / Year
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Formlabs GmbH
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Senior SLS Materials Scientist
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Senior SLS Materials Scientist sought to lead groundbreaking 3D printing polymer development in Somerville, MA. This role demands deep expertise in materials science, thermoplastic engineering, and data-driven experimentation to bring new SLS materials from ideation to market. Enjoy a robust equi...
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United States , Somerville
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115000.00 - 142000.00 USD / Year
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Formlabs GmbH
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Senior Applied Scientist and Principal Applied Scientist
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Join Microsoft’s Core AI Speech Group in Redmond as a Senior or Principal Applied Scientist. Drive innovation in end-to-end speech modeling, deep learning, and multimodal integration with LLMs. Requires a PhD/MS in CS, EE, or related field with experience in statistics and predictive analytics. I...
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United States , Redmond
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Salary
119800.00 USD / Year
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Microsoft Corporation
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Senior Scientist, Analytical Projects - Device, Particle Size and XRPD
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Senior Scientist, Analytical Projects sought in Collegeville, PA to lead device, particle size, and XRPD analysis. You will design experiments, validate methods, and interpret data to drive product development. Requires a Bachelor’s in analytical chemistry or related field with 3+ years’ lab expe...
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United States , Collegeville
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Not provided
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GSK
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Senior Data Scientist, AI & Model Risk
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Senior Data Scientist, AI & Model Risk in New York. Lead AI risk assessments for Generative AI and LLMs, applying Model Risk Management principles. Requires 5+ years in quantitative fields, Python proficiency, and deep knowledge of transformer models and RAG systems. Enjoy remote work, medical in...
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United States , New York
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Salary
139000.00 - 225000.00 USD / Year
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Cash App
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Senior Data Scientist, Guest Travel Insurance (Algorithms)
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Senior Data Scientist role on Airbnb’s AirCover team, focusing on ML-driven personalization for Guest Travel Insurance. You will build recommendation systems, intent models, and content personalization algorithms using Python, SQL, and TensorFlow/PyTorch. Requires 5+ years of industry experience ...
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United States
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179000.00 - 210000.00 USD / Year
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Airbnb
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Senior Data & Applied Scientist
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Join Microsoft’s Global Skilling team as a Senior Data & Applied Scientist to drive AI-powered learning experiences. Leverage Python, SQL, and causal inference to analyze learner journeys, define success metrics, and optimize product strategy. Requires a Doctorate/Master’s in Data Science or rela...
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United States , Multiple Locations
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119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Senior Data Scientist - Optimization
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Senior Data Scientist sought for client-facing consulting role blending Optimization, Operations Research, and AI. Lead high-impact engagements, solving complex operational problems with advanced mathematical modeling. Requires 7+ years in data science, 2+ years in OR/Optimization, and Python/R s...
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United States , Remote
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Salary
144975.00 - 241265.00 USD / Year
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NTT DATA
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Senior Applied Scientist
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Join Microsoft’s Bing Multimedia AIGC team in Redmond as a Senior Applied Scientist to build state-of-the-art AI creation features for Bing and Copilot. You will research metrics, optimize data workflows, and apply machine learning to deliver rich, scalable consumer experiences. Ideal candidates ...
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United States , Redmond
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Salary
119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Senior Data Scientist
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Senior Data Scientist role at Microsoft Security in Redmond, WA. Design and ship production ML models, including LLM and agent-based systems, for compromise detection and fraud prevention. Requires a Bachelor's in a quantitative field with 4+ years experience, or equivalent, plus expertise in Pyt...
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United States , Redmond
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Salary
119800.00 - 234700.00 USD / Year
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Microsoft Corporation
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Senior Theoretical & Computational Scientist
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Senior Theoretical & Computational Scientist sought to lead fusion plasma physics research at Realta Fusion in Madison, WI. This role requires a PhD and 5+ years experience in MHD equilibrium, Extended-MHD simulations (NIMROD/JOREK), and PIC/RF heating tools. You will validate models on the WHAM ...
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United States , Madison
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Not provided
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Realta Fusion Inc.
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Senior Applied Scientist, AWS Marketplace Discovery
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Join AWS Marketplace Discovery as a Senior Applied Scientist to lead AI-powered search and recommendation systems. You’ll translate cutting-edge research into scalable solutions, driving personalization for global customers. Requires 3+ years in ML, recommender systems, and Python/Java/C++. Based...
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United States , New York; Austin; Seattle
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Not provided
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Amazon Pforzheim GmbH
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About the Senior Scientist role

Senior Scientist jobs represent a pinnacle of technical expertise and research leadership across industries ranging from technology and healthcare to environmental science and pharmaceuticals. Professionals in these roles are distinguished by their ability to independently drive complex, high-impact projects that push the boundaries of their field. Unlike junior or mid-level scientists, a Senior Scientist is expected to not only execute advanced research but also to define the strategic direction of projects, mentor junior team members, and translate scientific findings into tangible business or societal value. The core of the role involves designing and overseeing rigorous experiments, developing novel algorithms or methodologies, and analyzing large, often unstructured datasets to extract actionable insights.

In the tech sector, this frequently means architecting and deploying sophisticated machine learning models, from deep learning and natural language processing to reinforcement learning, to solve problems at scale. In life sciences or healthcare, it may involve designing clinical study protocols, validating diagnostic tools, or leading drug discovery efforts. A common thread across all Senior Scientist jobs is the responsibility for the entire lifecycle of a research initiative: from hypothesis generation and experimental design, through data collection and analysis, to the communication of results through publications, patents, or executive presentations. These professionals are also the bridge between pure research and practical application, ensuring that innovations are robust, scalable, and aligned with organizational goals.

The typical requirements for these positions are stringent, usually demanding a PhD in a relevant scientific discipline such as computer science, statistics, biology, chemistry, or engineering, coupled with several years of post-doctoral or industry experience. Essential skills include deep proficiency in programming languages like Python or R, mastery of statistical analysis and experimental design (including A/B testing), and a strong publication record. Beyond technical acumen, Senior Scientists must possess exceptional problem-solving abilities, strategic thinking, and the capacity to lead cross-functional teams. They must be excellent communicators, capable of explaining complex scientific concepts to non-experts and influencing key decisions.

Ultimately, Senior Scientist jobs are for those who want to be at the forefront of discovery, shaping the future of their field while delivering measurable results.