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Senior Scientist United Kingdom Jobs

41 Job Offers

Senior QC Scientist
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Senior QC Scientist role at a thriving CDMO in Greater Manchester. Lead hands-on testing and ensure GMP compliance for finished products. Requires a degree in Chemistry or related field, proven HPLC/UHPLC expertise, and experience with method validation. Join a growing team, mentor junior scienti...
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United Kingdom , Cheadle, Greater Manchester
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SRG
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Senior Applied Scientist
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Senior Applied Scientist sought to advance retrieval systems for Microsoft 365 Copilot in London. You will design scalable pipelines and ranking models for Search, Chat, and Agent experiences. Requires deep expertise in semantic, dense, or hybrid retrieval and a degree in Computer Science or rela...
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United Kingdom , London
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73800.00 - 121300.00 GBP / Year
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Microsoft Corporation
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Senior Data Scientist
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Senior Data Scientist sought by Genius Sports to build next-gen predictive sports models in London. You will develop algorithms calculating outcome probabilities using Python, machine learning (neural networks, Monte Carlo simulation), and statistical expertise. Ideal for candidates with a STEM M...
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United Kingdom , London
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Genius Sports
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Senior Data Scientist - GenAI & ML
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Senior Data Scientist sought to lead GenAI & ML projects for Risk & Trading at CRU Group in London. You will own end-to-end delivery of predictive models, LLM-based AI agents, and production-grade Python solutions. Requires MSc+, expert Python (Pandas, Scikit-learn), 3-5+ years in data science, t...
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United Kingdom , London
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CRU International
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Senior Data Scientist
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Senior Data Scientist sought by a high-growth tech firm in London to drive strategic data product innovation. This individual contributor role demands strong Python, SQL, and machine learning skills to build predictive models and scalable solutions from large datasets. You will solve complex oper...
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United Kingdom , London
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100000.00 - 130000.00 GBP / Year
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Data Idols
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Senior Data Scientist AI Tooling
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Senior Data Scientist, AI Tooling role in London. Drive measurable GTM impact by designing and shipping AI-powered internal tools, leveraging LLMs, RAG, and vector search. Own the full lifecycle from problem definition to production, using Python, SQL, and orchestration tools. Join a fast-growing...
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United Kingdom , London
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Intercom
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Senior Data Scientist
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Senior Data Scientist sought to lead production ML at WPP in London. You will architect agentic AI pipelines, fine-tune LLMs (LoRA, RLHF), and deploy RAG systems at scale. Requires 5+ years shipping ML models, deep NLP/LLM expertise, and strong engineering habits. Benefits include remote work, fl...
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United Kingdom , London
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Satalia
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Senior Machine Learning Scientist
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Senior Machine Learning Scientist sought in Oxford, UK to lead ML strategy and deliver innovative modelling for high-impact projects. Requires a PhD, deep expertise in Python, PyTorch, and TensorFlow, plus a strong track record in applied problem-solving. Drive scientific rigour, author publicati...
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United Kingdom , Oxford
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65000.00 - 70000.00 GBP / Year
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360 Resourcing Solutions
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Senior Data Scientist - Industry Solutions Engineering
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Join Microsoft’s Industry Solutions Engineering team as a Senior Data Scientist in London. You’ll co-engineer innovative solutions with global customers, applying statistical modeling and data science expertise. Ideal for candidates with a PhD/Master’s in Data Science or related fields, plus expe...
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United Kingdom , London
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Microsoft Corporation
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Senior Machine Learning Scientist (Experiences)
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Senior Machine Learning Scientist sought by Tripadvisor’s Experiences R&D team in London. You will lead technical ML projects, designing custom models and optimizing production systems using deep learning frameworks like PyTorch. Requires 5+ years deploying large-scale models, expertise in MTL, r...
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United Kingdom , London
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Tripadvisor
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Senior Data Scientist
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Senior Data Scientist sought for a hands-on individual contributor role within Credit Risk Technology at a global financial institution in London. You will develop and deploy advanced Machine Learning solutions, from concept to production, with a focus on responsible AI and model governance. Key ...
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United Kingdom , London
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Citi
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Ophthalmology Bioassay Senior Scientist
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Join a pioneering CRO in Nottingham as an Ophthalmology Bioassay Senior Scientist. You will develop next-generation human-relevant ocular disease models using iPSC-derived systems and 3D organoids. This role combines hands-on bioassay design, imaging, and molecular biology with commercial impact....
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United Kingdom , Nottingham
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SRG
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Senior Data Scientist
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Senior Data Scientist sought to lead advanced ML and analytical solutions in the West Midlands, UK. You will drive production-ready models, mentor teams, and collaborate across data, AI, and engineering. Key skills include Python/R, model validation, and responsible AI. Ideal for experienced prof...
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United Kingdom , West Midlands
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AWTG
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Senior Data Scientist
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Senior Data Scientist sought for a high-impact Commercial team in Group Protection, Hove. This hands-on role involves designing insurance products, applying machine learning, and delivering end-to-end data science solutions. You will manipulate large datasets, build production models, and transla...
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United Kingdom , Hove
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LegalAndGeneral
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Senior Data Scientist
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Senior Data Scientist sought by a high-growth fintech scale-up for a hands-on role building and deploying production-grade ML and AI/LLM systems. You will leverage Python, SQL, and AWS to extract insights and develop NLP and Generative AI solutions. Fully remote position in the UK offering a comp...
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United Kingdom
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80000.00 - 100000.00 GBP / Year
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Oho Group Ltd
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Senior Data Scientist
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Senior Data Scientist sought to design and deliver end-to-end data science solutions for UK public and private sector clients. You will leverage expertise in Python, predictive analytics, computer vision, NLP, and MLOps on major cloud platforms. Based in London, this role offers a profit share sc...
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United Kingdom , London
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59400.00 - 78800.00 GBP / Year
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Softwire
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Senior Data Scientist
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Senior Data Scientist role at Cox Automotive Europe, based in Manchester. You will build production-grade machine learning models for pricing intelligence, stock segmentation, and buyer profiling within a product-led Decision Engine. Requires strong data science fundamentals, MLOps experience, an...
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United Kingdom , Manchester
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85000.00 GBP / Year
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Pavers
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Senior Metallurgist – Materials Scientist (CCGT)
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Senior Metallurgist / Materials Scientist sought for a permanent role in Derby, UK. Lead failure analysis and asset integrity projects within the power industry, leveraging expertise in high-temperature degradation and creep. Join TUV Rheinland’s expanding team, offering hybrid work, car allowanc...
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United Kingdom , Derby
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Risktec Solutions
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Senior Data Scientist
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Join a pioneering AI startup in London as a Senior Data Scientist. Design and deploy ML models for user behavior prediction and churn modeling, using Python on real-world data. Enjoy high autonomy, equity, and a hybrid role, directly shaping the core product with the founders.
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United Kingdom , London
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85000.00 - 95000.00 GBP / Year
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Data Idols
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Senior Applied Scientist
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Join our Cambridge team to advance M365 Copilot by fine-tuning LLMs on enterprise data. As a Senior Applied Scientist, you'll design, build, and deploy cutting-edge AI applications and agentic systems. We seek experts with strong R&D skills in cloud-based ML and a passion for transforming enterpr...
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United Kingdom , Cambridge
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Microsoft Corporation
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About the Senior Scientist role

Senior Scientist jobs represent a pinnacle of technical expertise and research leadership across industries ranging from technology and healthcare to environmental science and pharmaceuticals. Professionals in these roles are distinguished by their ability to independently drive complex, high-impact projects that push the boundaries of their field. Unlike junior or mid-level scientists, a Senior Scientist is expected to not only execute advanced research but also to define the strategic direction of projects, mentor junior team members, and translate scientific findings into tangible business or societal value. The core of the role involves designing and overseeing rigorous experiments, developing novel algorithms or methodologies, and analyzing large, often unstructured datasets to extract actionable insights.

In the tech sector, this frequently means architecting and deploying sophisticated machine learning models, from deep learning and natural language processing to reinforcement learning, to solve problems at scale. In life sciences or healthcare, it may involve designing clinical study protocols, validating diagnostic tools, or leading drug discovery efforts. A common thread across all Senior Scientist jobs is the responsibility for the entire lifecycle of a research initiative: from hypothesis generation and experimental design, through data collection and analysis, to the communication of results through publications, patents, or executive presentations. These professionals are also the bridge between pure research and practical application, ensuring that innovations are robust, scalable, and aligned with organizational goals.

The typical requirements for these positions are stringent, usually demanding a PhD in a relevant scientific discipline such as computer science, statistics, biology, chemistry, or engineering, coupled with several years of post-doctoral or industry experience. Essential skills include deep proficiency in programming languages like Python or R, mastery of statistical analysis and experimental design (including A/B testing), and a strong publication record. Beyond technical acumen, Senior Scientists must possess exceptional problem-solving abilities, strategic thinking, and the capacity to lead cross-functional teams. They must be excellent communicators, capable of explaining complex scientific concepts to non-experts and influencing key decisions.

Ultimately, Senior Scientist jobs are for those who want to be at the forefront of discovery, shaping the future of their field while delivering measurable results.