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Senior Python Developer Jobs (Remote work)

14 Job Offers

Senior Python Developer (US)
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Senior Python Developer role building backend apps, APIs, and AI-enabled software with LLMs and RAG. Requires 5+ years Python, AWS, and RESTful API experience. Fully remote US position, $125k-$145k plus benefits.
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JBS Dev
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Senior Python Backend Developer / ML Engineer (IR-555)
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Senior Python Backend Developer/ML Engineer needed to build scalable FastAPI systems and production LLM solutions. Requires 7+ years Python, 2+ years ML/LLM experience, RAG architectures, LangChain, and vector databases. Remote-friendly with flexible hours and growth opportunities.
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Intellectsoft
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Creative Tech | Senior Python Developer
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Devoteam
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Python Developer - Senior
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Devsu
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Senior Open-Source Python Engineer, ML Developer Tools - US Remote
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Hugging Face
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Senior Open-Source Python Engineer, ML Developer Tools - EMEA Remote
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Hugging Face
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Senior Fullstack AI Developer (Python + React)
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Devsu
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Senior Python Backend Developer / Platform Engineer- remote
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Inetum
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Senior Python Developer (CRM - AI/LLM)
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Emerging Travel Group
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Senior Full Stack Developer - Django / Python / Javascript
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Digital Forge Cyber Assurance Group
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Senior Python Developer | Reef Technologies [ 45-75 USD or 190-295 PLN per hour]
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Poland, Remote but only within Poland
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Bee Talents
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Senior Full Stack Developer (Python + React)
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Sigma Software Group
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Senior Ai Python Developer
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Hivex
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Senior Python developer
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Hivex
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About the Senior Python Developer role

Looking for Senior Python Developer jobs? You are exploring a pivotal role at the intersection of advanced software engineering, architectural leadership, and complex problem-solving. A Senior Python Developer is far more than just a coder; they are a technical authority responsible for designing, building, and maintaining robust, scalable applications that drive core business functions. This senior-level position demands a blend of deep technical expertise, strategic vision, and mentorship capabilities, making it a critical career step for experienced software professionals.

Typically, professionals in these jobs take ownership of the full software development lifecycle for sophisticated Python-based systems. Common responsibilities include architecting high-performance solutions, translating complex business requirements into technical specifications, and establishing coding standards and best practices for the team. They are often tasked with optimizing applications for speed and scalability, particularly when handling large-volume data computation, analytics, and processing. A key aspect of the role involves guiding and mentoring mid-level and junior developers, conducting code reviews, and fostering a culture of technical excellence. Senior Python Developers frequently collaborate with cross-functional teams, including product managers, data scientists, and business analysts, to ensure technical strategies align with overarching business goals. They are also expected to proactively research and integrate new technologies, frameworks, and methodologies to keep the technology stack modern and efficient.

The typical skill set for these positions is extensive. Expert-level proficiency in core Python and its ecosystem is non-negotiable, with deep knowledge of key libraries like Pandas, NumPy, and scientific computing stacks for data-intensive roles, or frameworks like Django or Flask for web-centric positions. A strong foundation in computer science fundamentals—data structures, algorithms, and system design—is essential. Experience with object-oriented programming (OOP), design patterns, and writing clean, maintainable, and testable code is standard. Most roles require proficiency with version control systems like Git, experience in cloud-native development and containerization (e.g., Docker, Kubernetes), and familiarity with CI/CD pipelines. Knowledge of database technologies, both SQL and NoSQL, and experience building and consuming RESTful APIs are also common requirements. Beyond technical acumen, successful candidates demonstrate strong analytical thinking, excellent communication skills, and the ability to lead projects and make high-impact decisions. A bachelor’s degree in computer science or a related field is typically expected, often supplemented by substantial professional experience.

Ultimately, Senior Python Developer jobs are for those who want to shape technology, not just implement it. It is a career path defined by technical leadership, innovation, and a direct impact on an organization's most critical systems and data-driven initiatives. If you are ready to leverage your advanced Python skills to solve complex challenges and lead technical strategy, exploring senior developer roles is your next logical step.