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Senior ML Engineer Jobs (Hybrid work)

14 Job Offers

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Senior ML Engineer, Agentic AI
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Lead Agentic AI innovation at Ellipsis Health in San Francisco. Architect scalable LLM-powered multi-agent systems, guide engineering pods, and translate frontier ML research into production. Requires 5+ years software development and deep Python/ML framework expertise.
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Ellipsis Health
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Senior ML Performance Engineer, Inference Optimisation
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Optimise transformer inference for edge accelerators and GPUs at Wayve in London. Hands-on role spanning compilers, runtimes and kernels, with strong CUDA/TensorRT skills required. Hybrid working, equity and relocation support offered.
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Wayve
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Senior ML Platform Engineer (GenAI Platform)
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Preply seeks a Senior ML Platform Engineer in Kyiv to build a GenAI platform with unified gateways, evaluation systems, and observability. Requires 5+ years backend/ML infrastructure, strong Python, and hands-on Agentic AI expertise.
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Preply
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Senior ML Platform Engineer (GenAI Platform)
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Join Preply as a Senior ML Platform Engineer in Barcelona to build a unified GenAI gateway with routing, caching, and observability. Requires 5+ years of backend/ML infra experience and strong Python skills.
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Preply
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Senior ML Platform Engineer (Agentic Platform)
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Preply seeks a Senior ML Platform Engineer in London to build a durable agentic platform with secure tool layers, state management and observability. Requires 5+ years backend/ML infra, strong Python and hands-on GenAI agent experience.
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Preply
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Senior ML Platform Engineer (GenAI Platform)
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Preply seeks a Senior ML Platform Engineer in London to build a GenAI platform with unified gateways, evaluation systems, and observability. Requires 5+ years in backend/ML infrastructure, strong Python, and hands-on Agentic AI expertise.
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Preply
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Senior AI & ML Engineer
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Nexthink
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Senior AI Researcher ML Engineer Cognitive Computing
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Athenacloud
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Senior Machine Learning (ML) Engineer
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Truveta
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Senior ML Engineer
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Datatonic
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Senior / Staff Machine Learning Engineer - ML Agents and Planning
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254000.00 - 366000.00 USD / Year
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Zoox
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Senior ML Engineer
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Datatonic
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Senior ML Compiler Engineer, Compute
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a16z
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Senior Engineer / Lead Engineer - Virtual Engineering - AI ML
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Senior/Lead Engineer – Virtual Engineering (AI/ML) in Bengaluru. Leverage ML to solve complex manufacturing challenges, executing end-to-end projects from ideation to deployment. Requires 5+ years in automotive manufacturing, Python, and frameworks like TensorFlow/PyTorch. Enjoy a hybrid role wit...
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General Motors
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About the Senior ML Engineer role

Senior ML Engineer jobs represent the pinnacle of technical leadership in the rapidly evolving field of artificial intelligence. Professionals in these roles are the critical bridge between theoretical data science and robust, scalable production systems. They are responsible for the entire machine learning lifecycle, transforming prototypes into reliable, high-impact applications that drive business value. A Senior ML Engineer typically possesses a deep blend of software engineering rigor, data architecture expertise, and applied machine learning knowledge, ensuring that models are not just accurate but also efficient, maintainable, and integrated seamlessly into broader technology ecosystems.

The core responsibilities of a Senior Machine Learning Engineer are multifaceted. They design, build, and maintain scalable data pipelines and infrastructure specifically optimized for ML workloads, which includes managing data ingestion, transformation (ETL/ELT), and storage solutions like feature stores and vector databases. A significant part of the role involves developing end-to-end ML pipelines that encompass data preparation, model training, validation, deployment (MLOps), and continuous monitoring in production. This includes implementing automated processes for retraining, performance tracking, and drift detection to ensure model longevity and accuracy. With the rise of Generative AI, these roles increasingly involve productionizing LLM-based applications and agentic workflows, focusing on aspects like latency, cost optimization, and observability. Furthermore, Senior ML Engineers enforce best practices around versioning, testing, and reproducibility using frameworks like MLflow. They ensure all systems adhere to stringent governance, security, and compliance standards while often leading strategic initiatives and mentoring junior team members.

To excel in Senior ML Engineer jobs, candidates generally need a strong foundation in computer science principles, statistics, and software engineering. A relevant Bachelor's or Master's degree is commonly required, coupled with 5+ years of hands-on experience in ML engineering or a closely related field. Proficiency in programming languages like Python and SQL is essential, along with extensive experience with cloud platforms (AWS, Azure, GCP) and big data technologies such as Apache Spark. Deep practical knowledge of machine learning frameworks (e.g., TensorFlow, PyTorch, Scikit-learn) and MLOps tools is mandatory. For modern roles, familiarity with NLP concepts, LLM application development frameworks (e.g., LangChain), and prompt engineering is highly valuable. Beyond technical skills, successful Senior ML Engineers demonstrate strong problem-solving abilities, clear communication to collaborate effectively with data scientists and business stakeholders, and a proactive, agile mindset to navigate the fast-paced AI landscape. They are leaders who drive innovation, set engineering standards, and take ownership of delivering complex, production-ready AI solutions.