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Senior machine learning engineer United States Jobs (Remote work)

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Senior Cognitive AI / Machine Learning Engineer
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Join a leading team leveraging AI and NLP to transform healthcare outcomes. As a Senior Machine Learning Engineer, you'll develop cloud-based solutions using Python and NoSQL. This role requires 5+ years' experience extracting insights from large datasets. Help shape the future of AI-powered heal...
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United States
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Not provided
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Nondestructive & Visual Inspection
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Senior Machine Learning System Engineer
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Join Atlassian's AI & ML Platform team as a Senior ML System Engineer. You will build core infrastructure for ML model lifecycle management, using Java/Kotlin, Python, and AWS. This remote US role offers a chance to impact millions of users while enjoying health benefits and paid volunteer time.
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United States , Seattle; San Francisco; New York; Austin
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165500.00 - 265800.00 USD / Year
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Atlassian
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Senior Machine Learning Engineering Manager
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Lead a core ML team at Atlassian, building advanced AI/ML models for revenue and forecasting. You'll manage the full ML lifecycle, from research to deployment, using cutting-edge techniques. Requires 5+ years managing ML engineering teams and a quantitative Master's/PhD. Role based in Seattle, Au...
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United States , Seattle; Austin; New York; Washington DC
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190300.00 - 305600.00 USD / Year
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Atlassian
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Senior Principal Machine Learning Systems Engineer
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Lead the development of foundational AI infrastructure at Atlassian as a Senior Principal ML Engineer. You will design systems, train complex models, and integrate AI capabilities across products. Requires 10+ years of ML experience, expertise in Python/Java, and cloud data platforms. Based in Se...
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United States , Seattle; San Francisco; Austin
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243100.00 - 407200.00 USD / Year
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Atlassian
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Senior Principal Machine Learning Engineer - LLM Post-Training and Optimization
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Lead the optimization of Large Language Models (LLMs) at Atlassian in Mountain View. This senior role requires deep expertise in transformer architectures, model fine-tuning, and techniques like quantization and distillation. You will deploy efficient, production-ready models in a collaborative e...
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United States , Mountain View
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243100.00 - 407200.00 USD / Year
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Atlassian
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Senior Staff Machine Learning Engineer
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Lead advanced ML initiatives at Affirm as a Senior Staff Machine Learning Engineer. Design and scale real-time systems using PyTorch, Transformers, and distributed infrastructure. Partner with cross-functional leaders to drive technical strategy and mentor senior engineers. Enjoy top benefits lik...
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United States
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232000.00 - 310000.00 USD / Year
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Affirm
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Senior Machine Learning Engineer, Financial Crimes
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Join CashApp's Financial Crimes team as a Senior Machine Learning Engineer. Use your 6+ years of ML expertise in NLP, GNNs, or RL to combat money laundering and terrorist financing. Design, deploy, and scale critical models in a fully remote role with top benefits. Help build a safer financial pl...
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United States , Bay Area
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194500.00 - 343100.00 USD / Year
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Cash App
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Senior Machine Learning Engineer
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Join Block's Support ML team to shape the future of AI-driven customer support. As a Senior Machine Learning Engineer, you'll build scalable LLM and generative AI systems for chatbots and voice interfaces. This remote role requires 6+ years of ML experience and expertise in NLP and production dep...
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United States , Bay Area
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Not provided
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Cash App
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Senior Machine Learning Engineer
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Join Spotify's Ad Engagement team in New York as a Senior Machine Learning Engineer. You will design ML systems to optimize ad performance, using MTL and Transformer models. Required expertise includes Python, TensorFlow/PyTorch, and data pipelines with Apache Beam/Spark. Enjoy top benefits like ...
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United States , New York
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184050.00 - 262928.00 USD / Year
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Spotify
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Senior Staff Machine Learning Engineer
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Lead the technical strategy for Spotify's core Home experience as a Senior Staff Machine Learning Engineer in New York. You will build large-scale, user-facing recommender systems using generative AI and advanced ML. This role requires deep production expertise across the full ML stack and offers...
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United States , New York
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264641.00 - 378058.00 USD / Year
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Spotify
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Senior Machine Learning Engineer
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Join Dropbox as a Senior Machine Learning Engineer to shape the future of AI-powered work. You will design and deploy large-scale ML and LLM systems, focusing on universal search and organization features. This US-based role requires 5+ years of ML/AI experience, expertise in Python/PyTorch, and ...
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United States
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196200.00 - 331800.00 USD / Year
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Dropbox
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Senior Machine Learning Engineering Manager, Gen AI
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Lead the development of Dropbox's AI product, Dash, as a Senior Machine Learning Engineering Manager. You will manage a team building Gen AI, NLP, and LLM solutions to drive product growth and monetization. This role requires 10+ years of software engineering experience and expertise in real-worl...
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United States
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216200.00 - 365700.00 USD / Year
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Dropbox
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Senior Machine Learning Engineer - Payments
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Join Plaid's core ML payments team in New York as a Senior Machine Learning Engineer. You will design, build, and deploy scalable AI/ML models using NLP, anomaly detection, and time series forecasting. This role requires 5+ years of production ML experience with Python, Spark, and distributed sys...
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United States , New York
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Salary
225600.00 - 337200.00 USD / Year
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Plaid
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Senior Machine Learning Engineer - Payments
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Join Plaid's core ML team in San Francisco as a Senior Machine Learning Engineer. Design, build, and deploy scalable AI/ML models that shape financial services for millions. Requires 5+ years of production ML experience, proficiency in Python/Spark, and a drive for high-impact ownership. Enjoy eq...
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United States , San Francisco
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Salary
225600.00 - 337200.00 USD / Year
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Plaid
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Discover and apply for Senior Machine Learning Engineer jobs, a pivotal role at the intersection of cutting-edge artificial intelligence and robust software engineering. Senior Machine Learning Engineers are the architects and builders who transform theoretical data science models into reliable, scalable, and impactful production systems. This senior-level profession is central to modern tech-driven companies, requiring a unique blend of advanced technical expertise, strategic thinking, and leadership. Professionals in these roles are primarily responsible for the end-to-end lifecycle of machine learning solutions. This begins with collaborating with data scientists and business stakeholders to understand complex problems and design appropriate algorithmic approaches. A core duty is developing, training, and rigorously evaluating models using a variety of techniques, from classical machine learning to deep learning and generative AI. However, their distinguishing skill is moving beyond experimentation to industrialize AI. They build the robust pipelines for data processing, feature engineering, and model deployment, ensuring solutions are scalable, maintainable, and integrated seamlessly into existing products and services. Furthermore, they establish monitoring frameworks to track model performance, data drift, and business impact in real-time, leading iterative improvements and retraining cycles. The typical skill set for Senior Machine Learning Engineer jobs is comprehensive. A strong foundation in computer science, mathematics, and statistics is non-negotiable. Proficiency in programming languages like Python and familiarity with frameworks such as TensorFlow or PyTorch is standard. Equally important is deep software engineering prowess, including knowledge of system design, APIs, containerization, and cloud infrastructure (AWS, Azure, GCP). Experience with MLOps practices, CI/CD for ML, and workflow orchestration tools is increasingly essential. Beyond technical acumen, these roles demand leadership qualities. Senior MLEs often mentor junior engineers, lead technical design reviews, and communicate complex concepts effectively to cross-functional teams and senior stakeholders. They are expected to stay abreast of rapid advancements in AI research and judiciously apply new methodologies to solve business challenges. When searching for Senior Machine Learning Engineer jobs, candidates should be prepared for roles that emphasize ownership and impact. Common requirements include an advanced degree in a quantitative field and several years of hands-on experience in building and deploying machine learning systems at scale. The profession offers the opportunity to shape the future of products and services, making it one of the most dynamic and sought-after careers in technology today. Explore opportunities to lead innovation and drive tangible value through applied artificial intelligence.

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