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Principal Technical Program Manager United States Jobs

59 Job Offers

Principal Technical Program Manager
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Global-e seeks a Principal Technical Program Manager in Hoboken to drive high-impact, cross-functional programs. This execution-focused role requires 7+ years of experience delivering complex initiatives with software engineering teams. You will define strategy, manage risk, and align stakeholder...
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United States , Hoboken
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Not provided
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Global-e
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Principal Technical Program Manager
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United States , Redmond
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Principal Technical Program Manager - Quantum
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Lead groundbreaking quantum hardware initiatives as a Principal Technical Program Manager at Microsoft in Redmond. Drive cross-disciplinary collaboration across quantum device physics, cryoelectronics, and cloud integration. Leverage AI to accelerate engineering workflows while managing strategic...
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United States , Redmond
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Principal Technical Program Manager (Quantum Hardware and Firmware Systems)
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United States , Redmond
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Principal Technical Program Manager - Applied Science
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United States , Redmond
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Principal Technical Program Manager
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Moderna seeks a visionary Principal Technical Program Manager to join the Digital Commercial Engineering team in Cambridge, MA. You will lead complex, cross-functional programs, translating business needs into scalable digital solutions that drive global commercial innovation. This role requires ...
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United States , Cambridge
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158600.00 - 285500.00 USD / Year
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Moderna
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Principal Technical Program Manager
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Lead the delivery of next-generation, runtime security defenses for Microsoft's agentic AI Copilot system. This Principal TPM role requires deep technical execution in high-ambiguity environments, translating threat models into durable solutions. You will drive cross-functional projects for adapt...
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United States , Redmond
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Principal Technical Program Manager
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Lead high-visibility generative AI advertising initiatives at Amazon Ads. This Principal TPM role in Seattle, Arlington, or New York requires 7+ years in technical program management and software development. You'll define roadmaps, resolve blockers, and launch innovative AI-driven advertising so...
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United States , Seattle; Arlington; New York
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177000.00 - 263400.00 USD / Year
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Amazon Pforzheim GmbH
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Principal Technical Program Manager
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Lead Microsoft's strategic AI initiatives as a Principal Technical Program Manager in Redmond. You will drive cross-organizational projects, shape technical strategy, and accelerate innovation with OpenAI technology. This role requires 6+ years in technical program management and expertise in man...
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United States , Redmond
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Principal Technical Program Manager
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Lead strategic security initiatives as a Principal Technical Program Manager within Microsoft's Cloud & AI CISO Office. You will define program goals and success metrics, managing complex, cross-functional projects. This Redmond-based role requires 6+ years in technical program management and a b...
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United States , Redmond
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Principal Technical Program Manager
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Lead high-impact security programs as a Principal Technical Program Manager at Microsoft in Redmond. Drive executive-level visibility and risk reduction across cloud and AI domains. Leverage 10+ years of technical program management experience in security or compliance. Shape strategy and deliver...
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United States , Redmond
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Principal Technical Program Manager
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Lead large-scale, cross-functional technical programs in Advertising and Pandora domains. This senior role requires 10+ years of TPM experience, expertise in ad tech, and driving engineering initiatives. Utilize your skills in Jira and stakeholder management to orchestrate impactful, revenue-crit...
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United States , Los Angeles; Washington; Atlanta; Boston
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185000.00 - 230000.00 USD / Year
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SiriusXM
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Principal Technical Program Manager - AI Frameworks
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Lead the orchestration of complex AI infrastructure at scale as a Principal Technical Program Manager at Microsoft in Redmond. You will drive execution, manage critical dependencies, and mitigate risks for next-generation AI frameworks. This role requires 8+ years in technical program management ...
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United States , Redmond
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163000.00 - 296400.00 USD / Year
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Microsoft Corporation
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Principal Technical Program Manager
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Lead technical program management for a leading IoT security company. Drive engineering process improvements and align initiatives with executive strategy in Boston. Requires 10+ years with software teams and 5+ in technical leadership. Enjoy a mission-driven culture, comprehensive benefits, and ...
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United States , Boston
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161000.00 - 237000.00 USD / Year
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SimpliSafe
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Principal Technical Program Manager
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Lead complex, cross-functional technical programs as a Principal TPM at Microsoft. Collaborate globally with customers and internal teams to develop innovative cloud solutions. This role requires 6+ years of engineering or program management experience and strong project leadership skills. Opport...
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United States , Multiple Locations
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Principal Technical Program Manager - New Product Introduction
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Lead New Product Introduction (NPI) and launch readiness at Microsoft in Redmond. Manage cross-functional programs with Engineering and Marketing to ensure flawless product releases. Requires 12+ years in technical program management and expertise in NPI processes. Drive customer experience and o...
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United States , Redmond
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Principal Technical Program Manager, Manager
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Lead a high-impact team as a Principal Technical Program Manager in Redmond, focusing on Microsoft's Cloud & AI security. You will define strategy and deliver complex, cross-functional programs to secure digital platforms. Requires 8+ years in technical program management and 3+ years of people m...
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United States , Redmond
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163000.00 - 296400.00 USD / Year
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Microsoft Corporation
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Principal Technical Program Manager
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Lead complex cloud solution development for capital markets clients as a Principal Technical Program Manager. Partner with Microsoft engineering teams and financial services customers to build innovative, scalable solutions. Requires 6+ years in technical program management and expertise in insid...
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United States , Multiple Locations
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Principal Technical Program Manager, Analytics - Microsoft AI Search
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Lead cross-organizational data and analytics initiatives for Bing Multimedia's AI-driven search experiences. Leverage your expertise in technical program management, data analysis, and metrics to accelerate insight generation and operational effectiveness. This senior role in Redmond requires 12+...
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United States , Redmond
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Senior Principal Technical Program Manager
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Lead AI-driven tooling and engineering systems strategy at Microsoft Research in Redmond. Manage cross-functional programs to accelerate AI/ML research and adoption. Requires 8+ years in technical program management and experience with large-scale AI infrastructure. Shape the future of agent-firs...
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United States , Redmond
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163000.00 - 296400.00 USD / Year
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Microsoft Corporation
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About the Principal Technical Program Manager role

Explore the world of Principal Technical Program Manager jobs and discover a senior leadership role that sits at the critical intersection of technology, business strategy, and execution. A Principal Technical Program Manager (Principal TPM) is a highly experienced professional responsible for spearheading an organization's most complex, high-impact, and often transformative technical initiatives. This is not a role focused on single projects; it is a strategic function dedicated to delivering large-scale programs that shape the future of a company's technology platform and product offerings. If you are a leader who thrives on solving intricate puzzles that span multiple engineering teams and business units, these jobs represent the pinnacle of technical program management.

Individuals in these jobs act as the central nervous system for major technical endeavors. Their primary mission is to bridge the gap between high-level business objectives and on-the-ground technical execution. A typical day involves orchestrating the efforts of engineers, architects, product managers, and executives to ensure a program's vision becomes a reality. Common responsibilities are multifaceted and strategic. They include developing and socializing long-term technical roadmaps, defining program scope and success metrics, and managing the entire lifecycle from conception to delivery. This involves meticulous planning, forecasting, and budgeting, as well as proactively identifying and mitigating risks that could derail a program. Furthermore, Principal TPMs are charged with managing complex, cross-functional dependencies and ensuring clear, consistent communication is flowing to all stakeholders, from engineering teams to the C-suite.

The skill set required for Principal Technical Program Manager jobs is both deep and broad. On the technical side, while they are not typically expected to write code, they must possess a profound understanding of software development lifecycles, system architecture, APIs, and infrastructure concepts like scalability, reliability, and performance. This technical acuity allows them to ask the right questions, understand engineering challenges, and facilitate effective decision-making. On the leadership and strategic side, these roles demand exceptional abilities. Strategic thinking is paramount, as is the capacity to translate ambiguous business goals into concrete, executable technical programs. Strong leadership and influence are essential for aligning diverse teams without direct authority, and outstanding communication skills are non-negotiable for articulating complex issues and program status to technical and non-technical audiences alike. Typically, these senior-level positions require a substantial track record, often 8+ years of experience in technical program management, engineering leadership, or a closely related field, with a proven history of leading large-scale, cross-organizational initiatives. For those seeking to drive technological innovation at the highest level, Principal Technical Program Manager jobs offer a challenging and immensely rewarding career path.