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Principal Process Engineer Jobs

17 Job Offers

Principal Process Engineer (Remote)
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Principal Process Engineer role in Tyler, US, seeking an FCC subject matter expert with 12+ years of refining experience. Drive safe, optimized refinery operations using Hysys/Pro/II modeling and catalyst expertise. Mentor junior engineers while maximizing product yield and unit profitability. Be...
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United States , Tyler
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Not provided
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Delek US
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Principal Engineer- Process & Product
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Principal Engineer (Process & Product) role in Aibonito, US. Lead manufacturing process optimization, new product introductions, and validations. Requires a Bachelor’s in Engineering with 5-8 years of experience, bilingual (Spanish/English), and project leadership skills. Enjoy comprehensive bene...
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United States of America , Aibonito
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Baxter
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Principal Engineer- Process & Product
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Lead Process & Product engineering initiatives in Aibonito, supporting manufacturing and new product development. This role requires a bilingual Engineer with 5-8 years of experience to manage projects and supervise operations. Baxter offers a robust benefits package including health coverage, re...
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United States of America , Aibonito
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Not provided
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Baxter
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Principal Process Safety / Functional Safety Engineer
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Lead process safety initiatives for a UK-based manufacturing leader. Facilitate key hazard studies (PHA/HAZOP/LOPA) and drive functional safety (SIL/SIS) in projects. Requires a Chemical Engineering degree, CFSE/TUV qualification, and strong risk assessment expertise. Enhance safety performance a...
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United Kingdom
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Not provided
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SRG
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Principal Process Engineer
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Qatar , Doha
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Lobellia
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Principal Engineer- Process & Product
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United States of America , Aibonito
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Baxter
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Principal Process Engineer
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United States , Bedford
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PCI Pharma Services
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Principal Process Engineer
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United States , Birmingham, AL
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Evonik Industries
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Principal Process Safety Engineer
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United States , Allentown; Mobile; Lafayette; Houston
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Evonik Industries
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Principal Process Engineer
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United States , Round Lake
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104000.00 - 143000.00 USD / Year
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Baxter
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Senior Principal Process Automation Engineer
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United States , Houston
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Airswift Sweden
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Principal Process Engineer
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Join our Round Lake site as a Principal Process Engineer. Drive process reliability and Industry 4.0 initiatives using automation, Six Sigma, and data integration. A Bachelor's in Engineering and 5+ years in a regulated manufacturing environment are required. We offer comprehensive benefits from ...
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United States , Round Lake
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104000.00 - 143000.00 USD / Year
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Baxter
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Drug Product Principal Process Engineer
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Lead complex engineering projects for sterile drug product fill-finish in Bedford, USA. This hands-on principal role requires 10+ years in pharma/biotech, with deep expertise in GMP, aseptic processes, and capital projects. Optimize state-of-the-art equipment, mentor engineers, and ensure world-c...
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United States , Bedford
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PCI Pharma Services
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Principal Process Engineer III
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Lead process engineering for offshore oil & gas facilities in the Gulf of Mexico and Trinidad. This Houston-based role requires 15+ years' experience, expertise in separation/dehydration/compression, and process safety. Provide technical support, optimize production, and manage brownfield project...
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United States , Houston
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Airswift Sweden
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Principal Process Automation Engineer
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Lead innovative automation projects in mining and energy sectors from Houston, Denver, or Calgary. This senior role requires expertise in PLC programming and full project lifecycle management, from concept to commissioning. Drive operational efficiency and safety using cutting-edge digital soluti...
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United States , Houston; Denver; Calgary
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Airswift Sweden
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Principal Process Engineer
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Lead process engineering for major mining projects across North America. This expat role requires 15+ years in mineral processing and EPC/EPCM, offering technical leadership and business growth. Enjoy a competitive salary, relocation support, and flexible work in a supportive culture. Based in Mo...
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Canada , Montreal; Toronto; Vancouver
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Primero Group
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Principal Process Engineer
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Lead major mining projects across North America as a Principal Process Engineer. This expat role in Canada/USA requires 15+ years in mineral processing and EPC/EPCM. Enjoy a competitive salary, relocation support, and a culture valuing technical excellence and work-life balance.
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Canada , Montreal; Toronto; Vancouver
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Primero Group
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About the Principal Process Engineer role

A Principal Process Engineer is a high-level technical expert responsible for designing, optimizing, and overseeing complex industrial processes across a wide range of sectors, including chemicals, pharmaceuticals, energy, food and beverage, and advanced manufacturing. These professionals are the bridge between fundamental scientific principles and practical, large-scale production, ensuring that operations are safe, efficient, cost-effective, and environmentally compliant. Searching for Principal Process Engineer jobs typically means looking for roles that demand deep technical mastery and significant leadership experience.

The core responsibility of a Principal Process Engineer is to lead the development of process designs from initial concept through to detailed engineering and commissioning. This involves creating critical documentation such as Process Flow Diagrams (PFDs) and Piping and Instrumentation Diagrams (P&IDs), performing complex heat and mass balance calculations, and conducting rigorous process simulations using specialized software like Aspen HYSYS or Pro/II. They are the go-to expert for troubleshooting operational issues, identifying bottlenecks, and recommending modifications to improve yield, throughput, and energy efficiency.

A significant portion of the role revolves around safety and risk management. Principal Process Engineers lead or actively participate in Hazard and Operability (HAZOP) studies, Layers of Protection Analysis (LOPA), and other safety reviews to identify potential hazards and ensure robust safeguards are in place. They also ensure all designs adhere to strict industry standards and regulatory requirements, such as those from the EPA, OSHA, or equivalent international bodies. Beyond technical design, these engineers are key mentors, training and developing junior engineers and fostering a culture of continuous improvement and technical excellence within their teams.

Typical requirements for these senior-level positions include a Bachelor’s degree in Chemical Engineering or a closely related field, with many employers preferring a Master’s degree. Employers seek candidates with substantial, demonstrable experience—often 10 to 15 years or more—in process engineering within a relevant industry. Deep expertise in one or more specific unit operations (such as distillation, reaction engineering, separation processes, or fluid catalytic cracking) is highly valued. Strong analytical skills, proficiency in process simulation and modeling tools, and exceptional communication abilities are essential for presenting complex data to both technical and non-technical stakeholders. Ultimately, Principal Process Engineer jobs are for seasoned professionals who combine deep technical knowledge with strategic thinking and strong leadership to drive operational excellence and innovation.