CrawlJobs Logo

Filters

Location
Salary

Principal Manufacturing Engineer Jobs

11 Job Offers

Principal Manufacturing Systems Engineer
Save Icon
Lead manufacturing systems innovation at Amgen in Thousand Oaks, CA. As Principal Manufacturing Systems Engineer, you will drive GMP-compliant automation projects, manage global standards, and oversee financials for core systems like Aveva PI and DeltaV. Requires a Doctorate with 2 years of leade...
Location Icon
Location
United States , Thousand Oaks
Salary Icon
Salary
Not provided
amgen.com Logo
Amgen
Expiration Date
Until further notice
Principal Manufacturing Engineer
Save Icon
Location Icon
Location
United States , Hayward
Salary Icon
Salary
112000.00 - 154000.00 USD / Year
https://www.baxter.com/ Logo
Baxter
Expiration Date
Until further notice
Principal Manufacturing Engineer
Save Icon
Principal Manufacturing Engineer sought in Hayward, CA to drive automation and process improvements in a medical device environment. Key responsibilities include troubleshooting PLCs, robotics, and high-speed packaging systems, plus leading capital projects. Requires a BS/MS in Engineering with 5...
Location Icon
Location
United States , Hayward
Salary Icon
Salary
112000.00 - 154000.00 USD / Year
https://www.baxter.com/ Logo
Baxter
Expiration Date
Until further notice
Principal Manufacturing Engineer
Save Icon
Principal Manufacturing Engineer role in Hayward, CA, driving automation and process improvements in a life-saving medical device environment. You will troubleshoot PLCs, robotics, and vision systems while leading capital projects. Requires a B.S. in Engineering with 5+ years of experience in pha...
Location Icon
Location
United States , Hayward
Salary Icon
Salary
112000.00 - 154000.00 USD / Year
https://www.baxter.com/ Logo
Baxter
Expiration Date
Until further notice
Principal Manufacturing Test Engineer
Save Icon
Location Icon
Location
United States , Secaucus
Salary Icon
Salary
141000.00 - 188000.00 USD / Year
sanmina.com Logo
Sanmina
Expiration Date
Until further notice
Principal Software Engineer, Manufacturing Intelligence
Save Icon
Location Icon
Location
United States , North Bethesda
Salary Icon
Salary
148000.00 - 193000.00 USD / Year
cherry.vc Logo
Cherry Ventures
Expiration Date
Until further notice
Principal Software Engineer, Manufacturing Intelligence
Save Icon
Location Icon
Location
United States , Lexington
Salary Icon
Salary
Not provided
cherry.vc Logo
Cherry Ventures
Expiration Date
Until further notice
Principal Software Engineer, Manufacturing Intelligence
Save Icon
Lead the technical design of AI-driven manufacturing solutions at Xometry. This senior role requires 8+ years of experience in cloud platforms, distributed systems, and hands-on coding leadership. You will mentor engineers and collaborate cross-functionally to predict manufacturing outcomes. The ...
Location Icon
Location
United States , Waltham
Salary Icon
Salary
148000.00 - 193000.00 USD / Year
cherry.vc Logo
Cherry Ventures
Expiration Date
Until further notice
Principal Software Engineer, Manufacturing Intelligence
Save Icon
Location Icon
Location
United States , Denver
Salary Icon
Salary
148000.00 - 193000.00 USD / Year
cherry.vc Logo
Cherry Ventures
Expiration Date
Until further notice
Principal Software Engineer, Manufacturing Intelligence
Save Icon
Location Icon
Location
United States , Los Angeles
Salary Icon
Salary
148000.00 - 193000.00 USD / Year
cherry.vc Logo
Cherry Ventures
Expiration Date
Until further notice
Principal Manufacturing Systems Engineer - Amgen Dun Laoghaire Project Delivery Lead
Save Icon
Lead IS/Automation project delivery for Amgen in Dun Laoghaire. This principal engineering role requires 8+ years in pharma/biotech manufacturing and expertise in PCS/MES systems. Drive innovation in a collaborative, science-based culture with a comprehensive benefits package. Make a lasting impa...
Location Icon
Location
Ireland , Dun Laoghaire
Salary Icon
Salary
Not provided
amgen.com Logo
Amgen
Expiration Date
Until further notice

About the Principal Manufacturing Engineer role

A Principal Manufacturing Engineer is a senior-level professional who plays a critical role in optimizing and overseeing complex manufacturing operations. These experts are responsible for designing, implementing, and improving production systems to enhance efficiency, reduce costs, and ensure product quality. In this highly specialized field, Principal Manufacturing Engineer jobs typically involve leading cross-functional teams to solve intricate technical challenges, from automating production lines to integrating advanced control systems. The core of this profession lies in bridging the gap between engineering design and practical, scalable production.

Common responsibilities for a Principal Manufacturing Engineer include developing and executing manufacturing strategies that align with long-term business goals. They often manage large-scale capital projects, overseeing budgets, timelines, and vendor performance. A significant part of the role involves troubleshooting and optimizing automated equipment, including programmable logic controllers (PLCs), robotics, and human-machine interfaces (HMIs). These professionals are also heavily involved in process validation, ensuring that all manufacturing activities comply with strict regulatory standards such as Good Manufacturing Practices (GMP) and quality management systems like ISO 13485 or ISO 9001. They lead root cause analysis for production issues, implement corrective actions, and drive continuous improvement initiatives. Additionally, Principal Manufacturing Engineers frequently mentor junior engineers and project managers, fostering a culture of technical excellence and innovation within their teams.

The typical skills and requirements for Principal Manufacturing Engineer jobs are extensive. Candidates must possess a strong educational background, usually a bachelor’s or master’s degree in mechanical, electrical, chemical, or biomedical engineering. This is complemented by significant hands-on experience—often five to ten years or more—in a manufacturing environment, particularly in regulated industries like pharmaceuticals, medical devices, or biotechnology. Technical expertise is paramount, with deep knowledge of automation systems, electromechanical design, and process control. Soft skills are equally important; these roles demand exceptional leadership, project management, and communication abilities to coordinate with stakeholders across quality, operations, IT, and corporate strategy. The ability to read complex schematics, manage multiple priorities, and make data-driven decisions under pressure is essential. In essence, Principal Manufacturing Engineer jobs are suited for seasoned engineers who combine technical mastery with strategic vision to drive manufacturing excellence and innovation.