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Principal Machine Learning Engineer Jobs

32 Job Offers

Principal Ai And Machine Learning Research Engineer
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Principal AI/ML Research Engineer sought by HPE Labs in Milpitas, CA. Lead groundbreaking research in analog in-memory computing and AI accelerator architectures. Requires a PhD with 5+ years experience in AI/ML and ReRAM expertise. Drive innovation from concept to reality in a collaborative, inc...
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United States of America , Milpitas
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160000.00 - 303000.00 USD / Year
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Hewlett Packard Enterprise
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Sr. Principal Machine Learning Engineer
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Universal Ads seeks a Sr. Principal Machine Learning Engineer to architect and scale the ML stack powering real-time ad delivery across CTV. This strategic leadership role involves setting the long-term vision for model architecture, distributed systems, and bidding algorithms. You will collabora...
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United States
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192396.16 - 450928.49 USD / Year
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Comcast Advertising
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Principal Machine Learning Engineer – Autonomy
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Lead the future of Physical AI as a Principal ML Engineer at Uber, shaping the core Autonomous Driving stack in San Francisco or Sunnyvale. You will define the technical vision for multi-modal systems, mentor top talent, and solve complex urban edge cases. Requires 10+ years in ML/Robotics, exper...
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United States , San Francisco; Sunnyvale
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302000.00 - 336000.00 USD / Year
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Uber
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Principal Machine Learning Engineer - Evisort AI
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Principal Machine Learning Engineer role at Workday’s Evisort AI, based in Seattle or Atlanta. You will develop tailored user experiences using advanced LLMs, Knowledge Graphs, and predictive analysis. Requires 10+ years building ML products at scale, expertise in PyTorch/TensorFlow, and 3+ years...
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USA , Seattle; Atlanta
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210600.00 - 316000.00 USD / Year
Workday
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Principal AI / Machine Learning Engineer
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Principal AI/ML Engineer to lead ZT’s manufacturing AI transformation in Secaucus, NJ. Requires 10-15 years in high-volume manufacturing, expertise in Python, R, SQL, and statistical methods (DOE, SPC). Drive smart factory vision, predictive analytics, and yield improvements. Benefits include com...
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United States , Secaucus
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141000.00 - 188000.00 USD / Year
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Sanmina
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Principal Machine Learning Engineer
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Principal Machine Learning Engineer sought by VideoAmp to architect advanced ML models and scalable infrastructure in Los Angeles, New York, or remote US hubs. Requires 7+ years in ML engineering, expert Python, Spark, AWS, and CI/CD skills. Lead cross-functional teams, drive data quality, and op...
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United States , Los Angeles; New York; Boulder; Chicago; Dallas; St. Petersburg
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184000.00 - 200000.00 USD / Year
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VideoAmp
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Staff / Principal Machine Learning Engineer, Serving
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Staff / Principal Machine Learning Engineer, Serving – UK. Join Inworld, a leading AI research lab backed by $125M+ from top investors, to optimize and deploy realtime multimodal models at scale. You will own full-cycle serving, from containerization to inference optimization and high-performance...
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United Kingdom
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140000.00 - 200000.00 GBP / Year
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Inworld AI
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Staff / Principal Machine Learning Engineer, Serving
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Staff / Principal Machine Learning Engineer role in Mountain View, CA, focused on inference optimization and model acceleration for agentic systems. You'll own full-cycle development of high-performance serving frameworks using vLLM, TRT-LLM, C++, CUDA, and distributed systems like Kubernetes. We...
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United States , Mountain View
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270000.00 - 500000.00 USD / Year
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Inworld AI
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Staff / Principal Machine Learning Engineer, Serving
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Inworld AI seeks a Staff/Principal Machine Learning Engineer to lead inference optimization for realtime multimodal models in Switzerland. You will drive model acceleration using quantization, speculative decoding, and frameworks like vLLM or TRT-LLM. Expertise in C++, CUDA, and distributed syste...
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Switzerland
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Not provided
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Inworld AI
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Principal Machine Learning Engineer
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Lead the design and operation of production-grade ML infrastructure at scale in Santa Clara. Architect robust pipelines, deploy models, and ensure reliability across the AI/ML ecosystem. Requires deep MLOps expertise, cloud platforms, and advanced inferencing techniques.
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United States , Santa Clara
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157200.00 - 254100.00 USD / Year
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Palo Alto Networks
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Principal Machine Learning Engineer
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Lead the development of a real-time recommendation engine for Zalando's Ad Tech platform in Berlin. As a Principal ML Engineer, you will architect scalable solutions, drive MLOps best practices, and mentor a cross-functional team. This hybrid role offers a competitive benefits package, including ...
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Germany , Berlin
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Not provided
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Zalando
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Principal Machine Learning Engineer
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Lead the development of a real-time recommendation engine for Zalando's Ad Tech platform in Berlin. As a Principal ML Engineer, you will architect scalable solutions, drive MLOps best practices, and mentor a cross-functional team. This hybrid role offers a competitive benefits package, including ...
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Germany , Berlin
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Not provided
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Zalando Sverige
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Principal Machine Learning Engineer
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Lead the architecture of a core AI/ML platform at Amgen in Hyderabad. You will design and build a scalable, self-service ecosystem for ML, LLM, and Generative AI models, enabling rapid research-to-production cycles. This senior role requires deep expertise in production ML systems, MLOps (MLflow)...
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India , Hyderabad
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Amgen
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Principal Machine Learning Engineer
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India , Bengaluru
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Ema
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Principal Machine Learning Engineer
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United States , Santa Clara
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185200.00 - 299475.00 USD / Year
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Palo Alto Networks
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Principal Machine Learning Engineer
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Canada
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192000.00 - 264000.00 CAD / Year
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Lime
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Principal Machine Learning Engineer
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United States
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240000.00 - 330000.00 USD / Year
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Lime
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Principal Machine Learning Engineer
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Lead the development of scalable ML systems for health and life sciences at Microsoft Health Futures. This principal role requires deep expertise in distributed model training, PyTorch/TensorFlow, and deploying large-scale MLops. Collaborate with a global team in Redmond to build next-generation ...
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United States , Redmond
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Principal Machine Learning Engineer
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Lead cutting-edge AI/ML projects to revolutionize IT operations and reduce resolution times. As a Principal Engineer in Bengaluru, you will architect scalable ML solutions, mentor engineers, and master Generative AI. Requires 10+ years of Python expertise and deep knowledge of TensorFlow/PyTorch,...
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India , Bengaluru
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Not provided
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Atlassian
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Principal Machine Learning System Engineer
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Lead the design and deployment of scalable ML systems and infrastructure in Seattle or San Francisco. Translate complex models into production-ready solutions, optimizing performance and reliability. Drive architectural decisions for cloud-based platforms while mentoring teams and promoting MLOps...
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United States , Seattle; San Francisco
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190300.00 - 305600.00 USD / Year
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Atlassian
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About the Principal Machine Learning Engineer role

Explore the world of Principal Machine Learning Engineer jobs and discover a senior leadership role at the apex of artificial intelligence and software engineering. A Principal Machine Learning Engineer is a strategic leader and technical visionary responsible for guiding an organization's most critical AI initiatives from conception to deployment at scale. This role transcends individual contribution, focusing on architectural design, technical strategy, and mentoring the next generation of talent.

Professionals in these jobs are the bridge between high-level business objectives and ground-level technical execution. Their day-to-day responsibilities are diverse and impactful. Typically, they lead the design and implementation of complex, scalable machine learning systems, making key decisions on architecture that affect the entire data science and engineering organization. They are tasked with researching and applying state-of-the-art techniques, whether in generative AI, natural language processing, computer vision, or deep learning, to solve fundamental business problems. A core part of their mandate is to establish and champion MLOps best practices, creating robust, automated pipelines for model training, evaluation, deployment, and monitoring to ensure models perform reliably in production environments. Furthermore, they provide technical leadership, mentoring senior and junior engineers, driving technical roadmaps, and collaborating cross-functionally with product managers, data scientists, and business stakeholders to align AI strategy with company goals.

The typical skill set for these high-level jobs is both deep and broad. A Principal Machine Learning Engineer possesses an expert-level understanding of machine learning theory, algorithms, and the practical trade-offs involved in model selection. Proficiency in programming languages like Python, along with mastery of frameworks such as TensorFlow, PyTorch, or JAX, is a given. Crucially, they have extensive experience in software engineering principles, distributed systems, and cloud platforms (like AWS, GCP, or Azure) to build resilient and scalable services. Strong skills in data engineering, including managing large-scale data pipelines with tools like Spark, are often essential. Beyond technical prowess, exceptional soft skills are non-negotiable. This includes superior communication abilities to articulate complex concepts to diverse audiences, proven project leadership, and a strategic mindset that balances long-term innovation with short-term business practicality.

Candidates for Principal Machine Learning Engineer jobs usually have a substantial track record, often requiring 8+ years of progressive experience in data science and machine learning, with a demonstrated history of deploying and maintaining models that deliver significant business value. A graduate degree (Master's or Ph.D.) in a quantitative field is common, though equivalent industry experience is highly valued. If you are seeking a role where you can set technical direction, solve the most challenging problems, and lead the creation of intelligent systems, exploring Principal Machine Learning Engineer jobs is your next strategic career move.