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Principal Machine Learning Engineer United States Jobs

15 Job Offers

Principal Engineer (Machine Learning)
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Seeking a Principal ML Engineer to drive AI-powered User and Entity Behavior Analytics in Santa Clara. You will architect and deploy cutting-edge ML models and pipelines using Python, TensorFlow, or PyTorch. Requires 10+ years in software development and 4+ years in backend engineering with ML ex...
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United States , Santa Clara
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185200.00 - 299475.00 USD / Year
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Palo Alto Networks
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Principal Machine Learning Engineer - AV Labs
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Join Uber’s AV Labs as a Principal ML Engineer to lead Physical AI innovation in San Francisco or Sunnyvale. You will architect state-of-the-art autonomy algorithms and foundation models, solving the hardest long-tail data challenges in autonomous driving. Requires 10+ years in ML/Robotics, exper...
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United States , San Francisco; Sunnyvale
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302000.00 - 336000.00 USD / Year
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Uber
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Principal Machine Learning Engineer, Agentic AI
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We are seeking a Principal Machine Learning Engineer to pioneer Agentic AI solutions in the United States. You will design and deploy multi-agent systems using LangChain/LangGraph, leveraging advanced GenAI models for autonomous, context-aware interactions. Ideal candidates possess 7+ years build...
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United States
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Not provided
Zillow
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Sr. Principal Machine Learning Engineer
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Universal Ads seeks a Sr. Principal Machine Learning Engineer to architect and scale the ML stack powering real-time ad delivery across CTV. This strategic leadership role involves setting the long-term vision for model architecture, distributed systems, and bidding algorithms. You will collabora...
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United States
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192396.16 - 450928.49 USD / Year
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Comcast Advertising
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Principal Machine Learning Engineer – Autonomy
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Lead the future of Physical AI as a Principal ML Engineer at Uber, shaping the core Autonomous Driving stack in San Francisco or Sunnyvale. You will define the technical vision for multi-modal systems, mentor top talent, and solve complex urban edge cases. Requires 10+ years in ML/Robotics, exper...
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United States , San Francisco; Sunnyvale
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302000.00 - 336000.00 USD / Year
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Uber
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Principal Machine Learning Engineer - Evisort AI
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Principal Machine Learning Engineer role at Workday’s Evisort AI, based in Seattle or Atlanta. You will develop tailored user experiences using advanced LLMs, Knowledge Graphs, and predictive analysis. Requires 10+ years building ML products at scale, expertise in PyTorch/TensorFlow, and 3+ years...
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USA , Seattle; Atlanta
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210600.00 - 316000.00 USD / Year
Workday
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Principal AI / Machine Learning Engineer
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Principal AI/ML Engineer to lead ZT’s manufacturing AI transformation in Secaucus, NJ. Requires 10-15 years in high-volume manufacturing, expertise in Python, R, SQL, and statistical methods (DOE, SPC). Drive smart factory vision, predictive analytics, and yield improvements. Benefits include com...
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United States , Secaucus
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141000.00 - 188000.00 USD / Year
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Sanmina
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Principal Machine Learning Engineer
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Principal Machine Learning Engineer sought by VideoAmp to architect advanced ML models and scalable infrastructure in Los Angeles, New York, or remote US hubs. Requires 7+ years in ML engineering, expert Python, Spark, AWS, and CI/CD skills. Lead cross-functional teams, drive data quality, and op...
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United States , Los Angeles; New York; Boulder; Chicago; Dallas; St. Petersburg
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184000.00 - 200000.00 USD / Year
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VideoAmp
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Staff / Principal Machine Learning Engineer, Serving
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Staff / Principal Machine Learning Engineer role in Mountain View, CA, focused on inference optimization and model acceleration for agentic systems. You'll own full-cycle development of high-performance serving frameworks using vLLM, TRT-LLM, C++, CUDA, and distributed systems like Kubernetes. We...
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United States , Mountain View
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270000.00 - 500000.00 USD / Year
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Inworld AI
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Principal Machine Learning Engineer
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United States , Santa Clara
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185200.00 - 299475.00 USD / Year
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Palo Alto Networks
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Principal Machine Learning Engineer
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United States
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240000.00 - 330000.00 USD / Year
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Lime
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Principal Machine Learning Engineer
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Lead the development of scalable ML systems for health and life sciences at Microsoft Health Futures. This principal role requires deep expertise in distributed model training, PyTorch/TensorFlow, and deploying large-scale MLops. Collaborate with a global team in Redmond to build next-generation ...
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United States , Redmond
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139900.00 - 274800.00 USD / Year
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Microsoft Corporation
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Staff / Principal Machine Learning Engineer
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Join our team in Mountain View as a Staff/Principal Machine Learning Engineer. You will research, build, and deploy production ML systems that power our next-generation AI platform. We require expertise in Python, PyTorch, and applied ML in NLP or speech. This role offers equity, bonus, and reloc...
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United States , Mountain View
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240000.00 - 385000.00 USD / Year
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Inworld AI
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Senior Principal Machine Learning Engineer
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Lead AI/ML strategy for Trust, Security, and Compliance at Atlassian. Architect scalable ML platforms and champion AI safety practices. Requires 12+ years of ML experience and expertise in Python/Go/Java. US-based role with comprehensive benefits and equity.
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United States
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222300.00 - 348975.00 USD / Year
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Atlassian
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Principal Machine Learning Computer Vision Engineer
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Lead the development of advanced computer vision solutions for manufacturing and aerospace industries in Bellevue. This senior role requires 7+ years of expertise in deep learning, OpenCV, PyTorch/TensorFlow, and production ML deployment on Azure. Design and optimize models for object detection a...
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United States , Bellevue
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Salary
160000.00 USD / Year
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Solomon Page
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About the Principal Machine Learning Engineer role

Explore the world of Principal Machine Learning Engineer jobs and discover a senior leadership role at the apex of artificial intelligence and software engineering. A Principal Machine Learning Engineer is a strategic leader and technical visionary responsible for guiding an organization's most critical AI initiatives from conception to deployment at scale. This role transcends individual contribution, focusing on architectural design, technical strategy, and mentoring the next generation of talent.

Professionals in these jobs are the bridge between high-level business objectives and ground-level technical execution. Their day-to-day responsibilities are diverse and impactful. Typically, they lead the design and implementation of complex, scalable machine learning systems, making key decisions on architecture that affect the entire data science and engineering organization. They are tasked with researching and applying state-of-the-art techniques, whether in generative AI, natural language processing, computer vision, or deep learning, to solve fundamental business problems. A core part of their mandate is to establish and champion MLOps best practices, creating robust, automated pipelines for model training, evaluation, deployment, and monitoring to ensure models perform reliably in production environments. Furthermore, they provide technical leadership, mentoring senior and junior engineers, driving technical roadmaps, and collaborating cross-functionally with product managers, data scientists, and business stakeholders to align AI strategy with company goals.

The typical skill set for these high-level jobs is both deep and broad. A Principal Machine Learning Engineer possesses an expert-level understanding of machine learning theory, algorithms, and the practical trade-offs involved in model selection. Proficiency in programming languages like Python, along with mastery of frameworks such as TensorFlow, PyTorch, or JAX, is a given. Crucially, they have extensive experience in software engineering principles, distributed systems, and cloud platforms (like AWS, GCP, or Azure) to build resilient and scalable services. Strong skills in data engineering, including managing large-scale data pipelines with tools like Spark, are often essential. Beyond technical prowess, exceptional soft skills are non-negotiable. This includes superior communication abilities to articulate complex concepts to diverse audiences, proven project leadership, and a strategic mindset that balances long-term innovation with short-term business practicality.

Candidates for Principal Machine Learning Engineer jobs usually have a substantial track record, often requiring 8+ years of progressive experience in data science and machine learning, with a demonstrated history of deploying and maintaining models that deliver significant business value. A graduate degree (Master's or Ph.D.) in a quantitative field is common, though equivalent industry experience is highly valued. If you are seeking a role where you can set technical direction, solve the most challenging problems, and lead the creation of intelligent systems, exploring Principal Machine Learning Engineer jobs is your next strategic career move.