Mid-Level Information System Security Officer jobs represent a critical and in-demand career path within the cybersecurity field, acting as the operational linchpin for an organization's information security compliance and risk management programs. Professionals in these roles are responsible for the day-to-day security of one or more information systems, ensuring they operate within established security frameworks and regulatory requirements. This position is ideal for cybersecurity practitioners who have moved beyond entry-level tasks and are ready to take ownership of system authorizations and continuous monitoring processes. Typically, a Mid-Level ISSO serves as the bridge between technical IT teams, system owners, and senior management or auditors. Their core mission is to achieve and maintain an authority to operate (ATO) for systems, most commonly within federal or highly regulated commercial environments like finance and healthcare. This involves a deep, practical understanding of governance, risk, and compliance (GRC) frameworks, especially the NIST Risk Management Framework (RMF). Daily and weekly responsibilities generally include maintaining and updating key system security documentation such as System Security Plans (SSPs), Plans of Action and Milestones (POA&Ms), and incident response plans. They conduct regular security control assessments, analyze vulnerability scan and audit log reports, and track remediation efforts to closure. A significant part of the role involves continuous monitoring to support ongoing authorization. This means the ISSO doesn't just prepare for an annual audit but actively monitors the system's security posture, reports on compliance metrics, and briefs leadership on risks and status. Collaboration is key, as they must work closely with system administrators and engineers to implement security controls and respond to security incidents effectively. Candidates seeking Mid-Level Information System Security Officer jobs typically possess a bachelor’s degree in cybersecurity, information technology, or a related field, coupled with 3-5 years of hands-on cybersecurity experience, specifically in compliance. Employers look for proven experience in shepherding a system through the RMF process and firsthand knowledge of security control families from NIST SP 800-53. Proficiency with security tools for vulnerability management and log analysis is standard. Given the communication-heavy nature of the job, strong written and verbal skills are paramount for drafting documentation and briefing stakeholders. Relevant industry certifications are highly valued and often required; these include CISSP, CISM, CGRC (formerly CAP), Security+, or CISA. Many of these roles, particularly those supporting government contracts, require the ability to obtain and maintain a security clearance. For professionals adept at translating technical vulnerabilities into business risk and ensuring systems remain compliant and resilient, Mid-Level ISSO jobs offer a challenging and rewarding career with significant growth potential into senior GRC or management positions.