Explore mid-level Information Systems Security Officer (ISSO) jobs and advance your career in a critical, high-demand field. An ISSO serves as the operational guardian of an organization's information systems, ensuring they meet stringent security standards and comply with federal regulations like FISMA, NIST frameworks, and industry-specific guidelines. Mid-level roles are perfect for professionals with foundational experience who are ready to take on greater responsibility in implementing and managing cybersecurity programs. In this pivotal position, typical daily responsibilities revolve around the continuous monitoring and protection of information assets. ISSOs develop, update, and maintain crucial documentation such as System Security Plans (SSPs), Risk Assessment Reports (RARs), and Plans of Action and Milestones (POA&Ms). They conduct regular security control assessments and audits to identify vulnerabilities, coordinating with IT teams to implement corrective actions and mitigate risks. A core function is managing the certification and accreditation (or Authorization to Operate - ATO) process for systems, ensuring all security controls are properly tested and documented before authorization. Furthermore, ISSOs play a key role in security awareness, training personnel on proper security protocols and incident response procedures. To succeed in mid-level ISSO jobs, candidates typically need a blend of specific technical knowledge and procedural expertise. Common requirements include a solid understanding of security frameworks (NIST SP 800-53, RMF), hands-on experience with security tools (vulnerability scanners, SIEM), and knowledge of network protocols and operating systems. Essential skills include strong analytical abilities for risk assessment, meticulous attention to detail for documentation, and excellent communication skills to liaise between technical teams and management or auditors. Most mid-level positions require a relevant bachelor’s degree and professional certifications such as Security+, CISSP, or CISM, along with 3-5 years of direct experience in information security or compliance roles. Pursuing mid-level ISSO jobs means stepping into a role with significant impact, where you directly shape an organization's security posture and resilience against evolving cyber threats. It is a career path offering robust growth, competitive compensation, and the satisfaction of safeguarding vital digital infrastructure.