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Information Systems Security Officer Jobs (On-site work)

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Information Systems Security Officer Level 3
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Seeking an experienced Information Systems Security Officer (ISSO) Level 3 in Annapolis Junction. This role ensures system compliance with NIST RMF and DoD policies, requiring 10 years' IT/cybersecurity experience and IAM I certification. Enjoy top-tier benefits including fully paid dental/vision...
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United States , Annapolis Junction
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Columbia Technology Partners
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Information Systems Security Officer
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Join AnaVation as a mid-level ISSO in Washington, DC. Provide security compliance expertise on critical projects, utilizing your NIST and FISMA experience. This role requires a Top-Secret clearance, on-site work, and focuses on SA&A packages and risk assessments. We offer competitive pay, generou...
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United States , Washington
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AnaVation
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Junior Information System Security Officer
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Launch your cybersecurity career as a Junior ISSO in Washington, DC. Support RMF compliance, ATO packages, and security monitoring for federal systems using tools like JCAM and Tenable. This role offers competitive pay, generous benefits, and a mission-driven environment to grow your GRC expertise.
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United States , Washington, DC
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AnaVation
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Mid-Level Information System Security Officer
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Join AnaVation's cybersecurity team in Washington, DC as a Mid-Level ISSO. Utilize your RMF expertise to manage ATOs, conduct security assessments, and ensure NIST compliance for federal systems. This role offers competitive pay, generous benefits, and requires a relevant degree, 4+ years' experi...
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United States , Washington, DC
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AnaVation
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Senior Information System Security Officer
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Lead critical cybersecurity efforts as a Senior ISSO in Washington, DC. This role requires expert RMF/NIST knowledge to manage ATO processes for high-impact federal systems. Mentor junior staff and ensure compliance while enjoying top-tier benefits like a 401k match and comprehensive health cover...
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United States , Washington
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AnaVation
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Information System Security Officer
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Join our cybersecurity team as an Information System Security Officer (ISSO) in Washington, DC. You will directly own the ATO process, ensuring compliance with NIST standards and managing POA&Ms. This role requires an active Top Secret/SCI clearance, IAT II certification, and experience with eMAS...
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United States , Washington, DC
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Barbaricum
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Senior Information Systems Security Officer
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Join 2HB Incorporated as a Senior ISSO in Annapolis Junction, MD. This role requires a TS/SCI/Full Scope Polygraph and DoD 8570 IAM Level II/IAT Level III certification (e.g., CISSP). You will enforce security policies, maintain operational posture, and perform risk assessments for critical IC/Do...
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United States , Annapolis Junction
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2HB
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Senior Information Systems Security Officer
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Join 2HB Incorporated as a Senior ISSO in Annapolis Junction, MD. This role requires a TS/SCI/Full Scope Polygraph, DoD 8570 IAM Level II/IAT Level III certification, and 12+ years of experience. You will enhance security posture, oversee system operations, and manage accreditation for critical I...
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United States , Annapolis Junction
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2HB
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Information Systems Security Officer Level 3
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Seeking an experienced Information Systems Security Officer (ISSO) Level 3 in Annapolis Junction. You will maintain operational security, enforce policies, and perform risk assessments for classified systems. Requires 10 years in IT/cybersecurity, a relevant Bachelor's degree, and expertise in se...
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United States , Annapolis Junction
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Columbia Technology Partners
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Information Systems Security Officer
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Seeking an experienced ISSO to lead cybersecurity compliance for the AFRL's RISE contract at Kirtland AFB, NM. This role requires an active TS/SCI clearance, CISSP, and 5+ years of DoD RMF experience. You will manage A&A packages, security controls, and risk assessments for critical space systems...
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United States , Albuquerque, New Mexico
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Astrion
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Cybersecurity - Information System Security Officer
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Join Boeing's Classified Cybersecurity team as an Information System Security Officer (ISSO). This role requires an active Top Secret clearance, IAM Level 1 certification, and 3+ years of RMF experience. You will lead A&A processes and ensure security compliance for classified systems in Berkeley...
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United States , Berkeley; Hazelwood; Saint Charles
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105400.00 - 142600.00 USD / Year
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Boeing
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Explore a critical and in-demand career path by searching for Information Systems Security Officer jobs. An Information Systems Security Officer (ISSO) is a cybersecurity professional responsible for ensuring that an organization's information systems are designed, operated, and maintained in a secure and compliant manner. These roles are fundamental across government, defense, and private sectors, serving as the crucial link between technical security controls, regulatory requirements, and organizational risk management. Professionals in this field act as stewards of information security, dedicated to protecting sensitive data and maintaining the integrity of critical IT infrastructure. The core mission of an ISSO is to achieve and maintain an Authority to Operate (ATO) or similar accreditation for systems. This involves a continuous lifecycle of security management. Typical responsibilities include developing and maintaining key documentation like System Security Plans (SSPs) and conducting regular risk assessments. ISSOs verify compliance with stringent security frameworks such as the National Institute of Standards and Technology (NIST) Risk Management Framework (RMF), Defense Information Systems Agency (DISA) Security Technical Implementation Guides (STIGs), and other federal or industry standards like FISMA or ISO 27001. They perform continuous monitoring, manage vulnerability scans using tools like Nessus or Qualys, and oversee the remediation of findings through Plans of Action and Milestones (POA&Ms). Furthermore, ISSOs collaborate closely with system owners, network engineers, and software developers to integrate security principles from the initial design phase through to deployment and operations, often within modern DevSecOps and cloud environments. To succeed in Information Systems Security Officer jobs, individuals typically need a blend of formal education, certifications, and hands-on experience. A bachelor’s degree in cybersecurity, information technology, computer science, or a related field is common. Industry-recognized certifications are frequently mandatory, particularly for roles supporting government contracts; these include CompTIA Security+, Certified Information Systems Security Professional (CISSP), Certified Information Security Manager (CISM), or Certified Ethical Hacker (CEH). Practical skills are paramount: a deep understanding of networking, operating systems (Windows/Linux), and cloud security (AWS, Azure, GCP) is essential. Candidates must be proficient in interpreting security policies, conducting audits, and managing accreditation packages in systems like eMASS. Strong analytical, communication, and problem-solving skills are vital, as ISSOs must translate complex technical vulnerabilities into business risk for leadership and work effectively with both technical and non-technical stakeholders. For many positions, particularly within the defense and intelligence communities, U.S. citizenship and the ability to obtain a security clearance are standard requirements. The landscape of Information Systems Security Officer jobs offers a challenging and rewarding career for those passionate about defending digital assets. It is a role that combines technical expertise with policy and procedure, offering professionals the opportunity to be at the forefront of an organization's cybersecurity posture. If you are detail-oriented, thrive on structure and compliance, and seek a position with significant impact, exploring ISSO opportunities could be your next career step.

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